Beneficial effects of combined therapy with lacidipine and candesartan in obese hypertensive patients

1. Ruilope Lm. Renal Function And Cardiovascular Risk In Hypertensive Patients. J Hypertension. 2005; 23(10): 1787-8.10.1097/01.hjh.0000183526.58499.65Search in Google Scholar

2. Dyer Ar., Elliott P., Stamler Sr., Stamler J. Body Mass Index And Association Of Sodium And Potassium With Blood Pressure In Lntersalt . Hypertension. 1994; 23:729-6.10.1161/01.HYP.23.6.729Search in Google Scholar

3. Nussinovitch U. The Heart In Rheumatic, Autoimmune And Inflammatory Disease Pathophysiology, Clinical Aspects And Therapeutic Approaches. Academic Press, 2017: 766.Search in Google Scholar

4. Kovalyova O., Belovol A., Zayika M. The Role Of Oxidative Stress In Cardiovascular Disease. J Academy Of Medical Sciences Of Ukraine. 2005; 11(4): 660-70.Search in Google Scholar

5. Kovalyova O., Ashcheulova T. Tumor Necrosis Factor-Α, Apoptosis In The Pathology Of Cardiovascular System. Original, Kharkiv, 2003: 95.Search in Google Scholar

6. Kovalyova O., Ashcheulova T., Gerasimchuk N. Relationship Of Immune Activation And Oxidative Stress In Patients With Hypertension And Their Correction Combined Antihypertensive Therapy. Scientific Bulletin Belsu Medicine Pharmacy. 2015; 16 (213) Issue 31: 52-9.Search in Google Scholar

7. Kovalyova O., Shapovalova S., Gerasimchuk N. Combination Therapy Of Hypertension. Pleiad, Kharkiv, 2005: 48.Search in Google Scholar

8. Kovalenko V., Nesukay E., Yakovenko A. Problems Of Diagnosis And Management Of Patients With Metabolic Syndrome. Ukrain J Of Cardiology, 2006; 4: 98-105.Search in Google Scholar

9. Sirenko Y. Dihydropyridine Calcium Channel Blockers - A New Provision To Reduce The Risk Of Complications Of Hypertension. J News Of Medicine And Pharmacy. 2009; 18 (292): 3-4.Search in Google Scholar

10. Mancia G., Fagard R., Narkiewicz K., Et Al. 2013 Esh/Esc Guidelines For The Management Of Arterial Hypertension: The Task Force For The Management Of Arterial Hypertension Of The European Society Of Hypertension (Esh) And Of The European Society Of Cardiology (Esc). European Heart J. 2013; 34(28): 2159-2219.10.1093/eurheartj/eht151Search in Google Scholar

11. World Health Organization. Obesity: Preventing And Managing The Global Epidemic. Who Technical Report Series. 2000: 1-252.Search in Google Scholar

12. Kovalyova O., Ashcheulova T., Gerasimchuk N., Safargalina-Kornilova N. The Role Of Oxidative Stress In The Formation And Progression Of Hypertension. Scientific Bulletin Belsu Medicine Pharmacy. 2015; 4(201) Issue 29: 5-10.Search in Google Scholar

13. Leonetti G., Magnani B., Rappelli A., Trimarco B., Zanchetti A. Et Al. Tolerability Of Long-Term Treatment With Lercanidipine Versus Amlodipine And Lacidipine In Elderly Hypertensives. Amer J Hypertension. 2002; 15(11): 932-940.10.1016/S0895-7061(02)03000-5Search in Google Scholar

14. Chung O., Unger T. Angiotensin Ii Receptor Blockade And End Organ Protection. Amer J Hypertension. 1999; 12:150-156.10.1016/S0895-7061(99)00218-6Search in Google Scholar

15. Ruiz-Ortega M., Lorenzo O., Suzuki Y., Rupérez M., Egido J. Proinflammatory Actions Of Anqiotensin П. Curr Opin Nephrol Hypertens. 2001; 10(3): 321-9.10.1097/00041552-200105000-0000511342793Search in Google Scholar

16. Ashcheulova T. Comparative Characteristics Of The Clinical Efficacy Of Inhibitors Of The Renin-Angiotensin System In Hypertension: Impact On Biomarkers Of Systemic Inflammation. Medical Practice. 2007; 3:48-51.Search in Google Scholar

17. Ambrosova T., Kovalyova O., Ashcheulova T. Therapeutic Potential Angiotensin Ii Receptor Antagonists In Patients With Arterial Hypertension With Metabolic Disorders: Effect On Carbohydrate And Lipid Profili. Ukrainian Therapeutical J. 2010; 4:17-22.Search in Google Scholar

18. Shargorodsky M., Hass E., Boaz M., Gavish D., Zimlichman R. High Dose Treatment With Angiotensin Ii Receptor Blocker In Patients With Hypertension: Differential Effect Of Protection Versus Blood Pressure Lowering. J Atherosclerosis. 2008; 197(1): 303-310.10.1016/j.atherosclerosis.2006.12.03617588581Search in Google Scholar

19. Mitchenko E.. Gulaya N., Viktorov A. Use Of Calcium Antagonists And No-State Change In Patients With Hypertension. Ukrain J Of Cardiology 2000; 1-2: 49-55.Search in Google Scholar

20. Zhang X., Hintze T.H. Amlodipine Releases Nitric Oxide From Canine Coronary Microvessels: An Unexpected Mechanism Of Action Of A Calcium Channel-Blocking Agent. Circulation. 1998; 97(6): 576-580.10.1161/01.CIR.97.6.576Search in Google Scholar

21. Black S.M., Fineman J.R., Steinhorn R.H., Bristow J., Soifer S.J. Increased Endothelial Nos In Lambs With Increased Pulmonary Blood Flow And Pulmonary Hypertension. Am J Physiol Soc.1998; 275(5): 1643-1651.10.1152/ajpheart.1998.275.5.H16439815072Search in Google Scholar

22. Taddei S., Virdis A., Ghiadoni L., Uleri S., Magagna A., Salvetti A. Lacidipine Restores Endotheliumdependent Vasodilation In Essential Hypertensive Patients. J Hypertension. 1997; 30(6): 1606-1612.10.1161/01.HYP.30.6.1606Search in Google Scholar

23. Krenek P., Salomone S., Kyselovic J., Wibo M., Morel N., Godfraind T. Lacidipine Prevents Endothelial Dysfunction In Salt Loaded Stroke Prone Hypertensive Rats. J Hypertension. 2001; 37: 1124-1128.10.1161/01.HYP.37.4.1124Search in Google Scholar

24. Svischenko E. Anti-Atherogenic Effect Of Lacidipine: Study Elsa (European Lacidipine Study On Atherosclerosis). Medicine Svіtu. 2002.Search in Google Scholar

25. Herbette L.G. The Interaction Of Lacidipine With Biological Membranes: The Molecular Of Calcium Antagonists. Rev Contemp Pharmacother.1995; 6(1): 8.Search in Google Scholar

26. Bernini F., Corsini A., Raiteri M., Soma M. R., Paoletti R. Effects Of Lacidipine On Experimental Models Of Atherosclerosis. J Of Hypertension. 1993; 11(Suppl 1): 61-66.10.1097/00004872-199303001-000118483025Search in Google Scholar

27. Soma M.R. Calcium Antagonists In Atherosclerosis: Focus On Lacidipine. Resesrch And Clinical Forums. 1994; 6(1): P. 543-551.Search in Google Scholar

28. Godfraind T. Effect Of Calcium Antagonist In Preclinical Models Of Atherosclerosis. The Elsa Study Results. Adis. 2002; 6-7.Search in Google Scholar