A Review of Chemotherapy and Radiotherapy Near the End of Life in Individuals with Metastatic Non-small Cell Lung Cancer

[1]Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the cost of cancer care in the United States: 2010–2020. J Natl Cancer Inst. 2011 Jan 19;103(2):117–28.MariottoABYabroffKRShaoYFeuerEJBrownMLProjections of the cost of cancer care in the United States: 2010–2020J Natl Cancer Inst2011Jan1910321172810.1093/jnci/djq495310756621228314Search in Google Scholar

[2]Glare P, Virik K, Jones M, Hudson M, Eychmuller S, Simes J, et al. A systematic review of physicians’ survival predictions in terminally ill cancer patients. BMJ. 2003 Jul 26;327(7408):195–8.GlarePVirikKJonesMHudsonMEychmullerSSimesJA systematic review of physicians’ survival predictions in terminally ill cancer patientsBMJ2003Jul263277408195810.1136/bmj.327.7408.19516612412881260Search in Google Scholar

[3]Chow E, Harth T, Hruby G, Finkelstein J, Wu J, Danjoux C. How accurate are physicians’ clinical predictions of survival and the available prognostic tools in estimating survival times in terminally ill cancer patients? A systematic review. Clin Oncol R Coll Radiol G B. 2001;13(3):209–18.ChowEHarthTHrubyGFinkelsteinJWuJDanjouxCHow accurate are physicians’ clinical predictions of survival and the available prognostic tools in estimating survival times in terminally ill cancer patients? A systematic reviewClin Oncol R Coll Radiol G B20011332091810.1007/s001740170078Search in Google Scholar

[4]Christakis NA, Lamont EB. Extent and determinants of error in physicians’ prognoses in terminally ill patients: prospective cohort study. West J Med. 2000 May;172(5):310–3.ChristakisNALamontEBExtent and determinants of error in physicians’ prognoses in terminally ill patients: prospective cohort studyWest J Med2000May1725310310.1136/ewjm.172.5.310107087618751282Search in Google Scholar

[5]Oxenham D, Cornbleet MA. Accuracy of prediction of survival by different professional groups in a hospice. Palliat Med. 1998 Mar;12(2):117–8.OxenhamDCornbleetMAAccuracy of prediction of survival by different professional groups in a hospicePalliat Med1998Mar122117810.1191/0269216986720342039616448Search in Google Scholar

[6]Nappa U, Lindqvist O, Rasmussen BH, Axelsson B. Palliative chemotherapy during the last month of life. Ann Oncol. 2011 Nov 1;22(11):2375–80.NappaULindqvistORasmussenBHAxelssonBPalliative chemotherapy during the last month of lifeAnn Oncol2011Nov1221123758010.1093/annonc/mdq77821402621Search in Google Scholar

[7]Murillo JR, Koeller J. Chemotherapy Given Near the End of Life by Community Oncologists for Advanced Non-Small Cell Lung Cancer. The Oncologist. 2006 Nov 1;11(10):1095–9.MurilloJRKoellerJChemotherapy Given Near the End of Life by Community Oncologists for Advanced Non-Small Cell Lung CancerThe Oncologist2006Nov111101095910.1634/theoncologist.11-10-109517110629Search in Google Scholar

[8]Emanuel EJ, Young-Xu Y, Levinsky NG, Gazelle G, Saynina O, Ash AS. Chemotherapy Use among Medicare Beneficiaries at the End of Life. Ann Intern Med. 2003 Apr 15;138(8):639–43.EmanuelEJYoung-XuYLevinskyNGGazelleGSayninaOAshASChemotherapy Use among Medicare Beneficiaries at the End of LifeAnn Intern Med2003Apr1513886394310.7326/0003-4819-138-8-200304150-0001112693886Search in Google Scholar

[9]Walasek T, Sas-Korczyńska B, Dąbrowski T, Reinfuss M, Jakubowicz J, Blecharz P, et al. Palliative thoracic radiotherapy for patients with advanced non-small cell lung cancer and poor performance status. Lung Cancer. 2015 Feb 1;87(2):130–5.WalasekTSas-KorczyńskaBDąbrowskiTReinfussMJakubowiczJBlecharzPPalliative thoracic radiotherapy for patients with advanced non-small cell lung cancer and poor performance statusLung Cancer2015Feb1872130510.1016/j.lungcan.2014.11.01525484031Search in Google Scholar

[10]Smith TJ, Temin S, Alesi ER, Abernethy AP, Balboni TA, Basch EM, et al. American Society of Clinical Oncology provisional clinical opinion: the integration of palliative care into standard oncology care. J Clin Oncol Off J Am Soc Clin Oncol. 2012 Mar 10;30(8):880–7.SmithTJTeminSAlesiERAbernethyAPBalboniTABaschEMAmerican Society of Clinical Oncology provisional clinical opinion: the integration of palliative care into standard oncology careJ Clin Oncol Off J Am Soc Clin Oncol2012Mar10308880710.1200/JCO.2011.38.516122312101Search in Google Scholar

[11]Stavas MJ, Pagan JD, Varma S, Li B, Kachnic LA. Building a palliative radiation oncology program: From bedside to B.E.D. Pract Radiat Oncol [Internet]. 2016 Sep 13 [cited 2017 Apr 19];0(0). Available from: http://www.practicalradonc.org.proxy.library.vanderbilt.edu/article/S1879-8500(16)30183-7/fulltextStavasMJPaganJDVarmaSLiBKachnicLABuilding a palliative radiation oncology program: From bedside to B.E.DPract Radiat Oncol [Internet]2016Sep13[cited 2017 Apr 19];0(0). Available from: http://www.practicalradonc.org.proxy.library.vanderbilt.edu/article/S1879-8500(16)30183-7/fulltext10.1016/j.prro.2016.09.00628277261Search in Google Scholar

[12]West L, Cole S, Goodkind D, He W. 65+ in the United States: 2010, United States Census Bureau. [Internet]. [cited 2017 Jun 12]. Available from: https://www.census.gov/content/dam/Census/library/publications/2014/demo/p23-212.pdfWestLColeSGoodkindDHeW65+ in the United States: 2010, United States Census Bureau[Internet]. [cited 2017 Jun 12]. Available from: https://www.census.gov/content/dam/Census/library/publications/2014/demo/p23-212.pdfSearch in Google Scholar

[13]Certification Levels [Internet]. [cited 2016 Apr 26]. Available from: http://naaccr.org/Certification/CertificationLevels.aspxCertification Levels[Internet]. [cited 2016 Apr 26]. Available from: http://naaccr.org/Certification/CertificationLevels.aspxSearch in Google Scholar

[14]The Florida Cancer Data System Home Page [Internet]. [cited 2016 Apr 26]. Available from: https://fcds.med.miami.edu/inc/welcome.shtmlThe Florida Cancer Data System Home Page [Internet][cited 2016 Apr 26]. Available from: https://fcds.med.miami.edu/inc/welcome.shtmlSearch in Google Scholar

[15]Earle CC, Neville BA, Landrum MB, Ayanian JZ, Block SD, Weeks JC. Trends in the Aggressiveness of Cancer Care Near the End of Life. J Clin Oncol. 2004 Jan 15;22(2):315–21.EarleCCNevilleBALandrumMBAyanianJZBlockSDWeeksJCTrends in the Aggressiveness of Cancer Care Near the End of LifeJ Clin Oncol2004Jan152223152110.1200/JCO.2004.08.13614722041Search in Google Scholar

[16]Guadagnolo BA, Liao K-P, Elting L, Giordano S, Buchholz TA, Shih Y-CT. Use of Radiation Therapy in the Last 30 Days of Life Among a Large Population-Based Cohort of Elderly Patients in the United States. J Clin Oncol. 2013 Jan 1;31(1):80–7.GuadagnoloBALiaoK-PEltingLGiordanoSBuchholzTAShihY-CTUse of Radiation Therapy in the Last 30 Days of Life Among a Large Population-Based Cohort of Elderly Patients in the United StatesJ Clin Oncol2013Jan131180710.1200/JCO.2012.45.0585353069323169520Search in Google Scholar

[17]Tiwana MS, Barnes M, Kiraly A, Olson RA. Utilization of palliative radiotherapy for bone metastases near end of life in a population-based cohort. BMC Palliat Care. 2016;15:2.TiwanaMSBarnesMKiralyAOlsonRAUtilization of palliative radiotherapy for bone metastases near end of life in a population-based cohortBMC Palliat Care201615210.1186/s12904-015-0072-5470700926748495Search in Google Scholar

[18]Kapadia NS, Mamet R, Zornosa C, Niland JC, D’Amico TA, Hayman JA. Radiation therapy at the end of life in patients with incurable nonsmall cell lung cancer. Cancer. 2012 Sep 1;118(17):4339–45.KapadiaNSMametRZornosaCNilandJCD’AmicoTAHaymanJARadiation therapy at the end of life in patients with incurable nonsmall cell lung cancerCancer2012Sep11181743394510.1002/cncr.2740122252390Search in Google Scholar

[19]Weeks JC, Catalano PJ, Cronin A, Finkelman MD, Mack JW, Keating NL, et al. Patients’ Expectations about Effects of Chemotherapy for Advanced Cancer. N Engl J Med. 2012 Oct 25;367(17):1616–25.WeeksJCCatalanoPJCroninAFinkelmanMDMackJWKeatingNLPatients’ Expectations about Effects of Chemotherapy for Advanced CancerN Engl J Med2012Oct253671716162510.1056/NEJMoa1204410361315123094723Search in Google Scholar

[20]Chen AB, Cronin A, Weeks JC, Chrischilles EA, Malin J, Hayman JA, et al. Expectations About the Effectiveness of Radiation Therapy Among Patients With Incurable Lung Cancer. J Clin Oncol. 2013 Jul 20;31(21):2730–5.ChenABCroninAWeeksJCChrischillesEAMalinJHaymanJAExpectations About the Effectiveness of Radiation Therapy Among Patients With Incurable Lung CancerJ Clin Oncol2013Jul2031212730510.1200/JCO.2012.48.5748370905823775958Search in Google Scholar

[21]Lewis JM, DiGiacomo M, Currow DC, Davidson PM. Dying in the margins: understanding palliative care and socioeconomic deprivation in the developed world. J Pain Symptom Manage. 2011 Jul;42(1):105–18.LewisJMDiGiacomoMCurrowDCDavidsonPMDying in the margins: understanding palliative care and socioeconomic deprivation in the developed worldJ Pain Symptom Manage2011Jul4211051810.1016/j.jpainsymman.2010.10.26521402460Search in Google Scholar

[22]Yabroff KR, Kim Y. Time costs associated with informal caregiving for cancer survivors. Cancer. 2009 Sep 15;115(18 Suppl):4362–73.YabroffKRKimYTime costs associated with informal caregiving for cancer survivorsCancer2009Sep1511518 Suppl43627310.1002/cncr.2458819731345Search in Google Scholar

[23]Dionne-Odom JN, Azuero A, Lyons KD, Hull JG, Tosteson T, Li Z, et al. Benefits of Early Versus Delayed Palliative Care to Informal Family Caregivers of Patients With Advanced Cancer: Outcomes From the ENABLE III Randomized Controlled Trial. J Clin Oncol Off J Am Soc Clin Oncol. 2015 May 1;33(13):1446–52.Dionne-OdomJNAzueroALyonsKDHullJGTostesonTLiZBenefits of Early Versus Delayed Palliative Care to Informal Family Caregivers of Patients With Advanced Cancer: Outcomes From the ENABLE III Randomized Controlled TrialJ Clin Oncol Off J Am Soc Clin Oncol2015May1331314465210.1200/JCO.2014.58.7824440442325800762Search in Google Scholar

[24]Barnato AE, Herndon MB, Anthony DL, Gallagher PM, Skinner JS, Bynum JPW, et al. Are Regional Variations in End-of-Life Care Intensity Explained by Patient Preferences? Med Care. 2007 May;45(5):386–93.BarnatoAEHerndonMBAnthonyDLGallagherPMSkinnerJSBynumJPWAre Regional Variations in End-of-Life Care Intensity Explained by Patient Preferences?Med Care2007May4553869310.1097/01.mlr.0000255248.79308.41214706117446824Search in Google Scholar

[25]Voogt E, Heide A van der, Rietjens JAC, Leeuwen AF van, Visser AP, Rijt CCD van der, et al. Attitudes of Patients With Incurable Cancer Toward Medical Treatment in the Last Phase of Life. J Clin Oncol. 2005 Mar 20;23(9):2012–9.VoogtEvan derHeide ARietjensJACvanLeeuwen AFVisserAPvan derRijt CCDAttitudes of Patients With Incurable Cancer Toward Medical Treatment in the Last Phase of LifeJ Clin Oncol2005Mar202392012910.1200/JCO.2005.07.10415774792Search in Google Scholar

[26]Finucane TE. Care of Patients Nearing Death: Another View. J Am Geriatr Soc. 2002 Mar 1;50(3):551–3.FinucaneTECare of Patients Nearing Death: Another ViewJ Am Geriatr Soc2002Mar1503551310.1046/j.1532-5415.2002.50125.x11943055Search in Google Scholar

[27]Matsuyama R, Reddy S, Smith TJ. Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2006 Jul 20;24(21):3490–6.MatsuyamaRReddySSmithTJWhy do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancerJ Clin Oncol Off J Am Soc Clin Oncol2006Jul2024213490610.1200/JCO.2005.03.623616849766Search in Google Scholar

[28]MedCrave. Geriatric oncology: where age is not measured by years. Int Clin Pathol J [Internet]. 2017 Dec 4 [cited 2019 Jun 3];Volume 5(Issue 4). Available from: http://medcraveonline.com/ICPJL/ICPJL-05-00136.pdfMedCraveGeriatric oncology: where age is not measured by yearsInt Clin Pathol J [Internet]2017Dec4[cited 2019 Jun 3];Volume 5(Issue 4). Available from: http://medcraveonline.com/ICPJL/ICPJL-05-00136.pdf10.15406/icpjl.2017.05.00136Search in Google Scholar

[29]Krishnan MS, Epstein-Peterson Z, Chen Y-H, Tseng YD, Wright AA, Temel JS, et al. Predicting Life Expectancy in Patients With Metastatic Cancer Receiving Palliative Radiotherapy: The TEACHH Model. Cancer. 2014 Jan 1;120(1):134–41.KrishnanMSEpstein-PetersonZChenY-HTsengYDWrightAATemelJSPredicting Life Expectancy in Patients With Metastatic Cancer Receiving Palliative Radiotherapy: The TEACHH ModelCancer2014Jan112011344110.1002/cncr.28408444710024122413Search in Google Scholar

[30]Kelly CM, Shahrokni A, Kelly CM, Shahrokni A. Moving beyond Karnofsky and ECOG Performance Status Assessments with New Technologies, Moving beyond Karnofsky and ECOG Performance Status Assessments with New Technologies. J Oncol J Oncol. 2016 Mar 15;2016, 2016:e6186543.KellyCMShahrokniAKellyCMShahrokniAMoving beyond Karnofsky and ECOG Performance Status Assessments with New Technologies, Moving beyond Karnofsky and ECOG Performance Status Assessments with New TechnologiesJ Oncol J Oncol2016Mar1520162016e618654310.1155/2016/6186543Search in Google Scholar

[31]Wright AA, Katz IT. Letting Go of the Rope — Aggressive Treatment, Hospice Care, and Open Access. N Engl J Med. 2007 Jul 26;357(4):324–7.WrightAAKatzITLetting Go of the Rope — Aggressive Treatment, Hospice Care, and Open AccessN Engl J Med2007Jul263574324710.1056/NEJMp07807417652646Search in Google Scholar

[32]Daugherty CK. Examining ethical dilemmas as obstacles to hospice and palliative care for advanced cancer patients. Cancer Invest. 2004;22(1):123–31.DaughertyCKExamining ethical dilemmas as obstacles to hospice and palliative care for advanced cancer patientsCancer Invest20042211233110.1081/CNV-12002758715069770Search in Google Scholar

[33]McGorty EK, Bornstein BH. Barriers to physicians’ decisions to discuss hospice: insights gained from the United States hospice model. J Eval Clin Pract. 2003 Aug 1;9(3):363–72.McGortyEKBornsteinBHBarriers to physicians’ decisions to discuss hospice: insights gained from the United States hospice modelJ Eval Clin Pract2003Aug1933637210.1046/j.1365-2753.2003.00406.x12895158Search in Google Scholar

[34]American Academy of Hospice and Palliative Medicine. Choosing Wisely Campaign® [Internet]. 2013. Available from: http://www.choosingwisely.org/clinician-lists/american-academy-hospice-palliative-care-dont-delay-palliative-care/American Academy of Hospice and Palliative MedicineChoosing Wisely Campaign® [Internet]2013Available from: http://www.choosingwisely.org/clinician-lists/american-academy-hospice-palliative-care-dont-delay-palliative-care/Search in Google Scholar

[35]Blumenthal D, Abrams M, Nuzum R. The Affordable Care Act at 5 Years. N Engl J Med. 2015 Jun 18;372(25):2451–8.BlumenthalDAbramsMNuzumRThe Affordable Care Act at 5 YearsN Engl J Med2015Jun18372252451810.1056/NEJMhpr150361425946142Search in Google Scholar

[36]Burwell SM. Setting Value-Based Payment Goals — HHS Efforts to Improve U.S. Health Care. N Engl J Med. 2015 Mar 5;372(10):897–9.BurwellSMSetting Value-Based Payment Goals — HHS Efforts to Improve U.S. Health CareN Engl J Med2015Mar537210897910.1056/NEJMp150044525622024Search in Google Scholar

[37]Ginsburg PB. Spending to Save — ACOs and the Medicare Shared Savings Program. N Engl J Med. 2011 Jun 2;364(22):2085–6.GinsburgPBSpending to Save — ACOs and the Medicare Shared Savings ProgramN Engl J Med2011Jun2364222085610.1056/NEJMp110360421612463Search in Google Scholar

[38]Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010 Aug 19;363(8):733–42.TemelJSGreerJAMuzikanskyAGallagherERAdmaneSJacksonVAEarly palliative care for patients with metastatic non-small-cell lung cancerN Engl J Med2010Aug1936387334210.1056/NEJMoa100067820818875Search in Google Scholar

[39]Wright AA, Zhang B, Ray A, et al. Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA. 2008 Oct 8;300(14):1665–73.WrightAAZhangBRayAAssociations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustmentJAMA2008Oct83001416657310.1001/jama.300.14.1665285380618840840Search in Google Scholar

[40]Jagsi R, Abrahamse P, Hawley ST, Graff JJ, Hamilton AS, Katz SJ. Underascertainment of radiotherapy receipt in Surveillance, Epidemiology, and End Results registry data. Cancer. 2012 Jan 15;118(2):333–41.JagsiRAbrahamsePHawleySTGraffJJHamiltonASKatzSJUnderascertainment of radiotherapy receipt in Surveillance, Epidemiology, and End Results registry dataCancer2012Jan1511823334110.1002/cncr.26295322468321717446Search in Google Scholar