<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.0904.422_s_001_w2aab3b7b9b1b6b1aab1c17b1Aa"><h3>Background</h3><p>There are limited data regarding background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) for Asian women.</p></sec><sec id="j_1905-7415.0904.422_s_002_w2aab3b7b9b1b6b1aab1c17b2Aa"><h3>Objectives</h3><p>To determine relationships between the amount of fibroglandular tissue (FGT) and BPE in breast MRI.</p></sec><sec id="j_1905-7415.0904.422_s_003_w2aab3b7b9b1b6b1aab1c17b3Aa"><h3>Methods</h3><p>A retrospective review identified 95 MRI examinations of women with normal breasts between March 2012 to July 2014 for inclusion in this study. BPE and MRI-FGT were assessed on precontrast T1-weighted fat-suppressed images by consensus and described according to the American College of Radiology Breast Imaging Reporting and Data System. We analyzed BPE, including early and peak enhancement (E<sub>early</sub>, E<sub>peak</sub>), and the signal enhancement ratio (SER). Spearman rank correlations between MRI-FGT and BPE and menopausal status were compared using Mann-Whitney <italic>U</italic> tests.</p></sec><sec id="j_1905-7415.0904.422_s_004_w2aab3b7b9b1b6b1aab1c17b4Aa"><h3>Results</h3><p>Fourteen premenopausal and 81 postmenopausal women had scattered and heterogeneous FGT (74%) and minimal to mild BPE (84%). There was a significant correlation between age and amount of MRI-FGT (<italic>r</italic> = -2.63; P = 0.01), but not BPE or enhancement kinetics. There was no significant correlation between FGT, BPE, and enhancement kinetics. There was a significant inverse relationship between menopause and the amount of FGT, BPE, and E<sub>peak</sub> (<italic>P</italic> &lt; 0.001, = 0.001, and = 0.04, respectively). There was no significant difference between pre and postmenopausal E<sub>early</sub> and SER (<italic>P</italic> > 0.05).</p></sec><sec id="j_1905-7415.0904.422_s_005_w2aab3b7b9b1b6b1aab1c17b5Aa"><h3>Conclusions</h3><p>There is no significant correlation between the amount of FGT and BPE in either premenopausal or postmenopausal women. The amount of FGT, degree of BPE, and E<sub>peak</sub> were higher in premenopausal women.</p></sec></abstract>

BackgroundThere are limited data regarding background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) for Asian women.ObjectivesTo determine relationships between the amount of fibroglandular tissue (FGT) and BPE in breast MRI.MethodsA retrospective review identified 95 MRI examinations of women with normal breasts between March 2012 to July 2014 for inclusion in this study. BPE and MRI-FGT were assessed on precontrast T1-weighted fat-suppressed images by consensus and described according to the American College of Radiology Breast Imaging Reporting and Data System. We analyzed BPE, including early and peak enhancement (Eearly, Epeak), and the signal enhancement ratio (SER). Spearman rank correlations between MRI-FGT and BPE and menopausal status were compared using Mann-Whitney U tests.ResultsFourteen premenopausal and 81 postmenopausal women had scattered and heterogeneous FGT (74%) and minimal to mild BPE (84%). There was a significant correlation between age and amount of MRI-FGT (r = -2.63; P = 0.01), but not BPE or enhancement kinetics. There was no significant correlation between FGT, BPE, and enhancement kinetics. There was a significant inverse relationship between menopause and the amount of FGT, BPE, and Epeak (P < 0.001, = 0.001, and = 0.04, respectively). There was no significant difference between pre and postmenopausal Eearly and SER (P > 0.05).ConclusionsThere is no significant correlation between the amount of FGT and BPE in either premenopausal or postmenopausal women. The amount of FGT, degree of BPE, and Epeak were higher in premenopausal women.

Fibroglandular tissue and quantitative background parenchymal enhancement on magnetic resonance breast images are inversely correlated with menopause in Thai women

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

BackgroundThere are limited data regarding background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) for Asian women.ObjectivesTo determine relationships between the amount of fibroglandular tissue (FGT) and BPE in breast MRI.MethodsA retrospective review identified 95 MRI examinations of women with normal breasts between March 2012 to July 2014 for inclusion in this study. BPE and MRI-FGT were assessed on precontrast T1-weighted fat-suppressed images by consensus and described according to the American College of Radiology Breast Imaging Reporting and Data System. We analyzed BPE, including early and peak enhancement (Eearly, Epeak), and the signal enhancement ratio (SER). Spearman rank correlations between MRI-FGT and BPE and menopausal status were compared using Mann-Whitney U tests.ResultsFourteen premenopausal and 81 postmenopausal women had scattered and heterogeneous FGT (74%) and minimal to mild BPE (84%). There was a significant correlation between age and amount of MRI-FGT (r = -2.63; P = 0.01), but not BPE or enhancement kinetics. There was no significant correlation between FGT, BPE, and enhancement kinetics. There was a significant inverse relationship between menopause and the amount of FGT, BPE, and Epeak (P  0.05).ConclusionsThere is no significant correlation between the amount of FGT and BPE in either premenopausal or postmenopausal women. The amount of FGT, degree of BPE, and Epeak were higher in premenopausal women.

BackgroundThere are limited data regarding background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) for Asian women.ObjectivesTo...

Fibroglandular tissue and quantitative background parenchymal enhancement on magnetic resonance breast images are inversely correlated with menopause in Thai women

Article Category: Brief communication (Original)

Published Online: Jan 31, 2017

Page range: 519 - 526

DOI: https://doi.org/10.5372/1905-7415.0904.422

Keywords
Background parenchymal enhancement (BPE), breast MRI correlation, fibroglandular tissue (FGT), menstruation, Thai women

© 2015 Anchukorn Rijiravanich, Jatuporn Chayakulkheeree

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fibroglandular tissue and quantitative background parenchymal enhancement on magnetic resonance breast images are inversely correlated with menopause in Thai women

Article Category: Brief communication (Original)

Published Online: Jan 31, 2017

Page range: 519 - 526

DOI: https://doi.org/10.5372/1905-7415.0904.422

KeywordsBackground parenchymal enhancement (BPE), breast MRI correlation, fibroglandular tissue (FGT), menstruation, Thai women

© 2015 Anchukorn Rijiravanich, Jatuporn Chayakulkheeree

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Background parenchymal enhancement (BPE), breast MRI correlation, fibroglandular tissue (FGT), menstruation, Thai women