1. bookVolume 11 (2011): Issue 4 (August 2011)
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Journal
eISSN
2300-8733
ISSN
1642-3402
First Published
25 Nov 2011
Publication timeframe
4 times per year
Languages
English
access type Open Access

Impact of Globulins Derived from Genetically Modified and Conventional Soybean on Swine Lymphocyte Proliferation in in vitro Cultures

Published Online: 25 Nov 2011
Volume & Issue: Volume 11 (2011) - Issue 4 (August 2011)
Page range: 497 - 505
Journal Details
License
Format
Journal
eISSN
2300-8733
ISSN
1642-3402
First Published
25 Nov 2011
Publication timeframe
4 times per year
Languages
English
Impact of Globulins Derived from Genetically Modified and Conventional Soybean on Swine Lymphocyte Proliferation in <italic>in vitro</italic> Cultures

The majority of the global feed market is dominated by the Roundup Ready 40-3-2 transgenic soybean varieties developed and marketed by Monsanto Company, which are characterized by tolerance to glyphosate, the active ingredient of the Roundup herbicide. It should be remembered, however, that soybean is one of the major allergens which may affect animal health. The aim of the study was to compare allergenic properties of globulins derived from genetically modified (GM) soybean imported from the USA and conventional soybean developed in Poland. Analyses were performed by measuring porcine lymphocyte proliferation in in vitro cultures. It turned out that both genetically modified and conventional soybean proteins caused immune response at the level of negative control. A slight increase in relation to the negative control was observed in the case of 7S and 11S fractions derived from the GM meal and 7S fraction isolated from Nawiko meal.

Keywords

Armstrong C.L., Mikel W.B., Stanisiewski E.P., Hartnell G.F. (2002). Soybean meal from Roundup Ready or conventional soybeans in diets for growing-finishing swine. J. Anim. Sci., 80: 708-715.Search in Google Scholar

Baranowski A., Rosochacki S., Parada R., Jaszczak K., Zimny J., Połoszynowicz J. (2006). The effect of diet containing genetically modified triticale on growth and transgenic DNA fate in selected tissues of mice. Anim. Sci. Pap. Rep., 24: 129-142.Search in Google Scholar

Berk Z. (1992). Technology of production of edible flours and protein products from soybeans. FAO Agricultural Services Bulletin no. 97, Food and Agriculture Organization of the United Nations, Roma.Search in Google Scholar

Besler M., Helm R.M., Ogawa T. (2000). Allergen data collection - update: Soybean (Glycine max), Internet Symposium on Food Allergens, 2: 1-35.Search in Google Scholar

Cromwell G.L., Lindemann M.D., Randolph J.H., Parker G.R., Coffey R.D., Laurent K.M., Hill J.E, Breidenbach R.W. (1974). Proteins of soybean seeds. Plant Physiol., 53: 742-746.Search in Google Scholar

Cromwell G.L., Lindemann M.D., Randolph J.H., Parker G.R., Coffey R.D., Laurent K.M., Armstrong C.L., Mikel W.B., Stanisiewski E.P., Hartnell G.F. (2002). Soybean meal from Roundup Ready or conventional soybeans in diets for growing-finishing swine. J. Anim. Sci., 80: 708-715.Search in Google Scholar

Holzhauser T., Wackermann O., Ballmer-Weber B.K., Bindslev-Jensen C., Scibilia J., Perono-Garoffo L., Utsumi S., Poulsen L.K., Vieths S. (2009). Soybean (Glycine max) allergy in Europe: Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) are potential diagnostic markers for severe allergic reactions to soy. J. Allergy Clin. Immunol., 123: 452-458.Search in Google Scholar

Jędrusek-Golińska A., Szymandera-Buszka K., Hęś M., Ziętara P. (2010). Knowledge on soybean, its preparations and allergenic properties among students of two universities in Poznań. Hygiea Public Health, 45: 177-180.Search in Google Scholar

Laszlo J.A. (1988). Content and bioavailability of minerals in soybean hulls. In: L. McCann (Ed.), Proceedings of Symposium on Soybean Utilization Alternatives, Sponsored by The Center for Alternative Crops and Products, US Department of Agriculture, Peoria, Illinois, pp. 333-341.Search in Google Scholar

Liu Ch., Wang H., Cui Z., He X., Wang X., Zeng X., Ma H. (2007). Optimization of extraction and isolation for 11S and 7S globulins of soybean seed storage protein. Food Chem., 102: 1310-1316.Search in Google Scholar

Nawracała J. (2000). Characteristics of soybean mutants obtained after chemical and physical mutagens treatment. Oilseed Crops, 1: 33-46.Search in Google Scholar

Padgette S.R, Biest T.N., Nida D.L., Bailey M.R., Mac Donald J., Holder L.R., Fuchs R.L. (1996). The composition of glyphosate-tolerant soybean seeds is equivalent to that of conventional soybeans. J. Nutr., 126: 702-716.Search in Google Scholar

SAS (1999). SAS User's guide. Statistics version 7th ed., SAS Inst Inc Cary NC.Search in Google Scholar

Song Y.S., Frias J., Martinem-Villaluenga C., Vidal-Valdeverde C. (2008). Immunoreactivity reduction of soybean meal by fermentation. Effect of amino acids composition and antigenicity of commercial soy products. Food Chem., 108: 571-581.Search in Google Scholar

Szymkiewicz A. (2007). Food allergens of plant origin. (In Polish), Przemysł Spożywczy, 7: 35-41.Search in Google Scholar

Świątkiewicz S., Koreleski J. (2008). Genetically modified plants in poultry nutrition. (In Polish). Med. Wet., 64: 1379-1383.Search in Google Scholar

Świątkiewicz S., Świątkiewicz M., Koreleski J., Kwiatek K. (2010). Nutritional efficiency of genetically modified, insect resistant corn (MON810) and glyphosate tolerant soybean meal (Roundup Ready) for broilers. Bull. Vet. Inst. in Puławy, 54: 43-48.Search in Google Scholar

Świątkiewicz M., Hanczakowska E., Twardowska M., Mazur M., Kwiatek K., Kozaczyński W., Świątkiewicz S., Sieradzki Z. (2011). Effect of genetically modified feeds on fattening results and transfer of transgenic DNA to swine tissues. Bull. Vet. Inst. Puławy, 55: 121-125Search in Google Scholar

Thanh Vu Huu, Okubo K., Shibasaki K. (1975). Isolation and characterization of the multiple 7S globulins of soybean proteins. Plant Physiol., 56, 19-22.10.1104/pp.56.1.1954129016659250Search in Google Scholar

Tsuji H., Kimoto M., Natori Y. (2001). Allergens in major crops. Nutr. Res., 21: 925-934.Search in Google Scholar

Twardowski T. (2011). Yet GM! (In Polish). Nauka, 1: 99-103.Search in Google Scholar

Wróblewska B. (2002). Big eight food allergens. (In Polish). Alergia, 4/15 (on line).Search in Google Scholar

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