<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Soy polysaccharides represent a multipurpose class of chemicals that include both therapeutical and technological properties. Since they have been first time introduced in the pharmaceutical field, Soy polysaccharides were used in two different pharmaceutical formulations; sublingual tablets and in colon drug delivery. For the sublingual tablets, Soy polysaccharides under the brand name of Emcosoy© - were used as a superdisintegrant in concentrations between 4-8% showing comparable results with the artificial superdisintegrants (sodium starch glycolate, sodium croscarmellose, and polyvinylpyrrolidone). The second technological field where Soy polysaccharides were used is represented by colon drug delivery where it was used in combination with ethylcellulose showing a prolonged lag time compared to the results found in the literature. The medicinal effect of these polysaccharides consists of treating diarrhea. As it will be presented in the article, these chemical compounds tend to decrease the aqueous stool time in patients with diarrhea and to conduct to a softer stool in healthy patients. In conclusion, these polysaccharides present multiple purposes possessing a medicinal effect and also the possibility of being used as a double-faceted pharmaceutical excipient.</p>
</abstract>

Soy polysaccharides represent a multipurpose class of chemicals that include both therapeutical and technological properties. Since they have been first time introduced in the pharmaceutical field, Soy polysaccharides were used in two different pharmaceutical formulations; sublingual tablets and in colon drug delivery. For the sublingual tablets, Soy polysaccharides under the brand name of Emcosoy© - were used as a superdisintegrant in concentrations between 4-8% showing comparable results with the artificial superdisintegrants (sodium starch glycolate, sodium croscarmellose, and polyvinylpyrrolidone). The second technological field where Soy polysaccharides were used is represented by colon drug delivery where it was used in combination with ethylcellulose showing a prolonged lag time compared to the results found in the literature. The medicinal effect of these polysaccharides consists of treating diarrhea. As it will be presented in the article, these chemical compounds tend to decrease the aqueous stool time in patients with diarrhea and to conduct to a softer stool in healthy patients. In conclusion, these polysaccharides present multiple purposes possessing a medicinal effect and also the possibility of being used as a double-faceted pharmaceutical excipient.

Soy polysaccharides therapeutic and technological aspects

Pharmaceutical Technology and Cosmetology Department

George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Analytical Chemistry and Drug Analysis Department

Drug Industry and Pharmaceutical Biotechnology Department

“Grigore T. Popa” University of Medicine and Pharmacy from Iaşi

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Soy polysaccharides therapeutic and technological aspects"}

Soy polysaccharides represent a multipurpose class of chemicals that include both therapeutical and technological properties. Since they have been first time...

Soy polysaccharides therapeutic and technological aspects

Article Category: REVIEW

Published Online: Dec 30, 2021

Page range: 199 - 203

Received: Jun 26, 2021

Accepted: Nov 12, 2021

DOI: https://doi.org/10.2478/amma-2021-0040

Keywords
soy polysaccharides, excipient, superdisintegrant, colon drug delivery, therapeutic effect

© 2021 Robert-Alexandru Vlad et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Soy polysaccharides therapeutic and technological aspects

Article Category: REVIEW

Published Online: Dec 30, 2021

Page range: 199 - 203

Received: Jun 26, 2021

Accepted: Nov 12, 2021

DOI: https://doi.org/10.2478/amma-2021-0040

Keywordssoy polysaccharides, excipient, superdisintegrant, colon drug delivery, therapeutic effect

© 2021 Robert-Alexandru Vlad et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
soy polysaccharides, excipient, superdisintegrant, colon drug delivery, therapeutic effect