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Long noncoding and micro-RNA expression in a model of articular chondrocyte degeneration induced by stromal cell-derived factor-1


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Jamshidi A, Pelletier JP, Martel-Pelletier J. Machine-learning-based patient-specific prediction models for knee osteoarthritis. Nat Rev Rheumatol. 2019; 15:49–60. JamshidiA PelletierJP Martel-PelletierJ Machine-learning-based patient-specific prediction models for knee osteoarthritis Nat Rev Rheumatol 2019 15 49 60 10.1038/s41584-018-0130-530523334 Search in Google Scholar

Nguyen US, Zhang Y, Zhu Y, Niu J, Zhang B, Felson DT. Increasing prevalence of knee pain and symptomatic knee osteoarthritis: survey and cohort data. Ann Intern Med. 2011; 155:725–32. NguyenUS ZhangY ZhuY NiuJ ZhangB FelsonDT Increasing prevalence of knee pain and symptomatic knee osteoarthritis: survey and cohort data Ann Intern Med 2011 155 725 32 10.7326/0003-4819-155-11-201112060-00004340802722147711 Search in Google Scholar

Aguiar GC, Queiroz-Junior CM, Sitta GL, Amaral FA, Teixeira MM, Caliari MV, Ferreira AJ. Mefenamic acid decreases inflammation but not joint lesions in experimental osteoarthritis. Int J Exp Pathol. 2016; 97:438–46. AguiarGC Queiroz-JuniorCM SittaGL AmaralFA TeixeiraMM CaliariMV FerreiraAJ Mefenamic acid decreases inflammation but not joint lesions in experimental osteoarthritis Int J Exp Pathol 2016 97 438 46 10.1111/iep.12216537022728370591 Search in Google Scholar

Jones IA, Togashi R, Wilson ML, Heckmann N, Vangsness CT Jr. Intra-articular treatment options for knee osteoarthritis. Nat Rev Rheumatol. 2019; 15:77–90. JonesIA TogashiR WilsonML HeckmannN VangsnessCTJr Intra-articular treatment options for knee osteoarthritis Nat Rev Rheumatol 2019 15 77 90 10.1038/s41584-018-0123-4639084330498258 Search in Google Scholar

Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol. 2008; 9:219–30. StefaniG SlackFJ Small non-coding RNAs in animal development Nat Rev Mol Cell Biol 2008 9 219 30 10.1038/nrm234718270516 Search in Google Scholar

Shi Z, Ning G, Zhang B, Yuan S, Zhou H, Pan B, et al. Signatures of altered long noncoding RNAs and messenger RNAs expression in the early acute phase of spinal cord injury. J Cell Physiol. 2019; 234:8918–27. ShiZ NingG ZhangB YuanS ZhouH PanB Signatures of altered long noncoding RNAs and messenger RNAs expression in the early acute phase of spinal cord injury J Cell Physiol 2019 234 8918 27 10.1002/jcp.2756030341912 Search in Google Scholar

Chen G, Wang Z, Wang D, Qiu C, Liu M, Chen X, et al. LncRNA-Disease: a database for long-non-coding RNA-associated diseases. Nucleic Acids Res. 2013; 41(Database issue):D983–6. ChenG WangZ WangD QiuC LiuM ChenX LncRNA-Disease: a database for long-non-coding RNA-associated diseases Nucleic Acids Res 2013 41 Database issue D983 6 10.1093/nar/gks1099353117323175614 Search in Google Scholar

Bao Z, Yang Z, Huang Z, Zhou Y, Cui Q, Dong D. LncRNADisease 2.0: an updated database of long non-coding RNA-associated diseases. Nucleic Acids Res. 2019; 47(D1):D1034–7. BaoZ YangZ HuangZ ZhouY CuiQ DongD LncRNADisease 2.0: an updated database of long non-coding RNA-associated diseases Nucleic Acids Res 2019 47 D1 D1034 7 10.1093/nar/gky905632408630285109 Search in Google Scholar

Kopańska M, Szala D, Czech J, Gabło N, Gargasz K, Trzeciak M, et al. MiRNA expression in the cartilage of patients with osteoarthritis. J Orthop Surg Res. 2017; 12:51. doi: 10.1186/s13018-017-0542-y. Erratum in: J Orthop Surg Res. 2017; 12:90. KopańskaM SzalaD CzechJ GabłoN GargaszK TrzeciakM MiRNA expression in the cartilage of patients with osteoarthritis J Orthop Surg Res 2017 12 51 10.1186/s13018-017-0542-y Erratum in: J Orthop Surg Res. 2017; 12:90. 537126628351380 Open DOISearch in Google Scholar

Fu M, Huang G, Zhang Z, Liu J, Zhang Z, Huang Z, et al. Expression profile of long noncoding RNAs in cartilage from knee osteoarthritis patients. Osteoarthritis Cartilage. 2015; 23:423–32. FuM HuangG ZhangZ LiuJ ZhangZ HuangZ Expression profile of long noncoding RNAs in cartilage from knee osteoarthritis patients Osteoarthritis Cartilage 2015 23 423 32 10.1016/j.joca.2014.12.00125524778 Search in Google Scholar

Sun H, Peng G, Ning X, Wang J, Yang H, Deng J. Emerging roles of long noncoding RNA in chondrogenesis, osteogenesis, and osteoarthritis. Am J Transl Res. 2019; 11:16–30. SunH PengG NingX WangJ YangH DengJ Emerging roles of long noncoding RNA in chondrogenesis, osteogenesis, and osteoarthritis Am J Transl Res 2019 11 16 30 Search in Google Scholar

Hu J, Wang Z, Shan Y, Pan Y, Ma J, Jia L. Long non-coding RNA HOTAIR promotes osteoarthritis progression via miR-17-5p/FUT2/b-catenin axis. Cell Death Dis. 2018; 9:711. doi: 10.1038/s41419-018-0746-z HuJ WangZ ShanY PanY MaJ JiaL Long non-coding RNA HOTAIR promotes osteoarthritis progression via miR-17-5p/FUT2/b-catenin axis Cell Death Dis 2018 9 711 10.1038/s41419-018-0746-z Open DOISearch in Google Scholar

Cen X, Huang X-Q, Sun W-T, Liu Q, Liu J. Long noncoding RNAs: a new regulatory code in osteoarthritis. Am J Transl Res. 2017; 9:4747–55. CenX HuangX-Q SunW-T LiuQ LiuJ Long noncoding RNAs: a new regulatory code in osteoarthritis Am J Transl Res 2017 9 4747 55 Search in Google Scholar

He Z, Jia M, Yu Y, Yuan C, Wang J. Roles of SDF-1/CXCR4 axis in cartilage endplate stem cells mediated promotion of nucleus pulposus cells proliferation. Biochem Biophys Res Commun. 2018; 506:94–101. HeZ JiaM YuY YuanC WangJ Roles of SDF-1/CXCR4 axis in cartilage endplate stem cells mediated promotion of nucleus pulposus cells proliferation Biochem Biophys Res Commun 2018 506 94 101 10.1016/j.bbrc.2018.10.069 Search in Google Scholar

Chen H-T, Tsou H-K, Hsu C-J, Tsai C-H, Kao C-H, Fong Y-C, Tang C-H. Stromal cell-derived factor-1/CXCR4 promotes IL-6 production in human synovial fibroblasts. J Cell Biochem. 2011; 112:1219–27. ChenH-T TsouH-K HsuC-J TsaiC-H KaoC-H FongY-C TangC-H Stromal cell-derived factor-1/CXCR4 promotes IL-6 production in human synovial fibroblasts J Cell Biochem 2011 112 1219 27 10.1002/jcb.23043 Search in Google Scholar

Dong Y, Liu H, Zhang X, Xu F, Qin L, Cheng P, et al. Inhibition of SDF-1a/CXCR4 signalling in subchondral bone attenuates post-traumatic osteoarthritis. Int J Mol Sci. 2016; 17:943. doi: 10.3390/ijms17060943 DongY LiuH ZhangX XuF QinL ChengP Inhibition of SDF-1a/CXCR4 signalling in subchondral bone attenuates post-traumatic osteoarthritis Int J Mol Sci 2016 17 943 10.3390/ijms17060943 Open DOISearch in Google Scholar

Wei L, Sun X, Kanbe K, Wang Z, Sun C, Terek R, Chen Q. Chondrocyte death induced by pathological concentration of chemokine stromal cell-derived factor-1. J Rheumatol. 2006; 33:1818–26. WeiL SunX KanbeK WangZ SunC TerekR ChenQ Chondrocyte death induced by pathological concentration of chemokine stromal cell-derived factor-1 J Rheumatol 2006 33 1818 26 Search in Google Scholar

Wang K, Li Y, Han R, Cai G, He C, Wang G, Jia D. T140 blocks the SDF-1/CXCR4 signaling pathway and prevents cartilage degeneration in an osteoarthritis disease model. PLoS One. 2017; 12:e0176048. doi: 10.1371/journal.pone.0176048 WangK LiY HanR CaiG HeC WangG JiaD T140 blocks the SDF-1/CXCR4 signaling pathway and prevents cartilage degeneration in an osteoarthritis disease model PLoS One 2017 12 e0176048 10.1371/journal.pone.0176048 Open DOISearch in Google Scholar

Kanbe K, Takagishi K, Chen Q. Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4. Arthritis Rheum. 2002; 46:130–7. KanbeK TakagishiK ChenQ Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4 Arthritis Rheum 2002 46 130 7 10.1002/1529-0131(200201)46:1<130::AID-ART10020>3.0.CO;2-D Search in Google Scholar

Kanbe K, Takemura T, Takeuchi K, Chen Q, Takagishi K, Inoue K. Synovectomy reduces stromal-cell-derived factor-1 (SDF-1) which is involved in the destruction of cartilage in osteoarthritis and rheumatoid arthritis. J Bone Joint Surg Br. 2004; 86:296–300. KanbeK TakemuraT TakeuchiK ChenQ TakagishiK InoueK Synovectomy reduces stromal-cell-derived factor-1 (SDF-1) which is involved in the destruction of cartilage in osteoarthritis and rheumatoid arthritis J Bone Joint Surg Br 2004 86 296 300 10.1302/0301-620X.86B2.14474 Search in Google Scholar

Li G, Yun X, Ye K, Zhao H, An J, Zhang X, et al. Long non-coding RNA-H19 stimulates osteogenic differentiation of bone marrow mesenchymal stem cells via the microRNA-149/SDF-1 axis. J Cell Mol Med. 2020; 24:4944–55. LiG YunX YeK ZhaoH AnJ ZhangX Long non-coding RNA-H19 stimulates osteogenic differentiation of bone marrow mesenchymal stem cells via the microRNA-149/SDF-1 axis J Cell Mol Med 2020 24 4944 55 10.1111/jcmm.15040 Search in Google Scholar

van Solingen C, de Boer HC, Bijkerk R, Monge M, van Oeveren-Rietdijk AM, Seghers L, et al. MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1+/Lin progenitor cells in ischaemia. Cardiovasc Res. 2011; 92:449–55. van SolingenC de BoerHC BijkerkR MongeM van Oeveren-RietdijkAM SeghersL MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1+/Lin progenitor cells in ischaemia Cardiovasc Res 2011 92 449 55 10.1093/cvr/cvr227 Search in Google Scholar

Periyasamy-Thandavan S, Burke J, Mendhe B, Kondrikova G, Kolhe R, Hunter M, et al. MicroRNA-141-3p negatively modulates SDF-1 expression in age-dependent pathophysiology of human and murine bone marrow stromal cells. J Gerontol A Biol Sci Med Sci. 2019; 74:1368–74. Periyasamy-ThandavanS BurkeJ MendheB KondrikovaG KolheR HunterM MicroRNA-141-3p negatively modulates SDF-1 expression in age-dependent pathophysiology of human and murine bone marrow stromal cells J Gerontol A Biol Sci Med Sci 2019 74 1368 74 10.1093/gerona/gly186 Search in Google Scholar

Altman RD. The classification of osteoarthritis. J Rheumatol Suppl. 1995; 43:42–3. AltmanRD The classification of osteoarthritis J Rheumatol Suppl 1995 43 42 3 Search in Google Scholar

Charalambous CP. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II: correlation of morphology with biochemical and metabolic data. In: Banaszkiewicz P, Kader D, editors. Classic papers in orthopaedics. London: Springer-Verlag; 2014, p. 385–7. CharalambousCP Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II: correlation of morphology with biochemical and metabolic data In: BanaszkiewiczP KaderD editors. Classic papers in orthopaedics London Springer-Verlag 2014 385 7 10.1007/978-1-4471-5451-8_97 Search in Google Scholar

Smoot ME, Ono K, Ruscheinski J, Wang P-L, Ideker T. Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics. 2011; 27:431–2. SmootME OnoK RuscheinskiJ WangP-L IdekerT Cytoscape 2.8: new features for data integration and network visualization Bioinformatics 2011 27 431 2 10.1093/bioinformatics/btq675303104121149340 Search in Google Scholar

Szklarczyk D, Gable AL, Nastou KC, Lyon D, Kirsch R, Pyysalo S, et al. The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets. Nucleic Acids Res. 2021; 49(D1):D605–12. SzklarczykD GableAL NastouKC LyonD KirschR PyysaloS The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets Nucleic Acids Res 2021 49 D1 D605 12 10.1093/nar/gkaa1074777900433237311 Search in Google Scholar

Pearson MJ, Philp AM, Heward JA, Roux BT, Walsh DA, Davis ET, et al. Long intergenic noncoding RNAs mediate the human chondrocyte inflammatory response and are differentially expressed in osteoarthritis cartilage. Arthritis Rheumatol. 2016; 68:845–56. PearsonMJ PhilpAM HewardJA RouxBT WalshDA DavisET Long intergenic noncoding RNAs mediate the human chondrocyte inflammatory response and are differentially expressed in osteoarthritis cartilage Arthritis Rheumatol 2016 68 845 56 10.1002/art.39520495000127023358 Search in Google Scholar

Li Y-F, Li S-H, Liu Y, Luo Y-T. Long noncoding RNA CIR promotes chondrocyte extracellular matrix degradation in osteoarthritis by acting as a sponge for Mir-27b. Cell Physiol Biochem. 2017; 43:602–10. LiY-F LiS-H LiuY LuoY-T Long noncoding RNA CIR promotes chondrocyte extracellular matrix degradation in osteoarthritis by acting as a sponge for Mir-27b Cell Physiol Biochem 2017 43 602 10 10.1159/00048053228934732 Search in Google Scholar

Zhang G, Wu Y, Xu D, Yan X. Long noncoding RNA UFC1 promotes proliferation of chondrocyte in osteoarthritis by acting as a sponge for miR-34a. DNA Cell Biol. 2016; 35:691–5. ZhangG WuY XuD YanX Long noncoding RNA UFC1 promotes proliferation of chondrocyte in osteoarthritis by acting as a sponge for miR-34a DNA Cell Biol 2016 35 691 5 10.1089/dna.2016.339727529373 Search in Google Scholar

Round JL, Lee SM, Li J, Tran G, Jabri B, Chatila TA, Mazmanian SK. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science. 2011; 332(6032):974–7. RoundJL LeeSM LiJ TranG JabriB ChatilaTA MazmanianSK The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota Science 2011 332 6032 974 7 10.1126/science.1206095316432521512004 Search in Google Scholar

Liu Y-X, Wang G-D, Wang X, Zhang Y-L, Zhang T-L. Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study. Oncotarget. 2017; 8:38602–17. LiuY-X WangG-D WangX ZhangY-L ZhangT-L Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study Oncotarget 2017 8 38602 17 10.18632/oncotarget.16199550355728418842 Search in Google Scholar

Parkinson-Lawrence EJ, Shandala T, Prodoehl M, Plew R, Borlace GN, Brooks DA. Lysosomal storage disease: revealing lysosomal function and physiology. Physiology (Bethesda). 2010; 25:102–15. Parkinson-LawrenceEJ ShandalaT ProdoehlM PlewR BorlaceGN BrooksDA Lysosomal storage disease: revealing lysosomal function and physiology Physiology (Bethesda) 2010 25 102 15 10.1152/physiol.00041.200920430954 Search in Google Scholar

Li P, Deng J, Wei X, Jayasuriya CT, Zhou J, Chen Q, et al. Blockade of hypoxia-induced CXCR4 with AMD3100 inhibits production of OA-associated catabolic mediators IL-1b and MMP-13. Mol Med Rep. 2016; 14:1475–82. LiP DengJ WeiX JayasuriyaCT ZhouJ ChenQ Blockade of hypoxia-induced CXCR4 with AMD3100 inhibits production of OA-associated catabolic mediators IL-1b and MMP-13 Mol Med Rep 2016 14 1475 82 10.3892/mmr.2016.5419494008327356492 Search in Google Scholar

Wilkins RJ, Browning JA, Ellory JC. Surviving in a matrix: membrane transport in articular chondrocytes. J Membr Biol. 2000; 177:95–108. WilkinsRJ BrowningJA ElloryJC Surviving in a matrix: membrane transport in articular chondrocytes J Membr Biol 2000 177 95 108 10.1007/s00232000110311003684 Search in Google Scholar

Mow VC, Guo XE. Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies. Annu Rev Biomed Eng. 2002; 4:175–209. MowVC GuoXE Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies Annu Rev Biomed Eng 2002 4 175 209 10.1146/annurev.bioeng.4.110701.12030912117756 Search in Google Scholar

Wojdasiewicz P, Poniatowski ŁA, Szukiewicz D. The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis. Mediators Inflamm. 2014; 2014:561459. doi: 10.1155/2014/561459 WojdasiewiczP PoniatowskiŁA SzukiewiczD The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis Mediators Inflamm 2014 2014 561459 10.1155/2014/561459 402167824876674 Open DOISearch in Google Scholar

Choy E. Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford). 2012; 51(Suppl 5):v3–11. ChoyE Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis Rheumatology (Oxford) 2012 51 Suppl 5 v3 11 10.1093/rheumatology/kes11322718924 Search in Google Scholar

Kobayashi M, Squires GR, Mousa A, Tanzer M, Zukor DJ, Antoniou J, et al. Role of interleukin-1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage. Arthritis Rheum. 2005; 52:128–35. KobayashiM SquiresGR MousaA TanzerM ZukorDJ AntoniouJ Role of interleukin-1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage Arthritis Rheum 2005 52 128 35 10.1002/art.2077615641080 Search in Google Scholar

Séguin CA, Bernier SM. TNFα suppresses link protein and type II collagen expression in chondrocytes: role of MEK1/2 and NF-κB signaling pathways. J Cell Physiol. 2003; 197:356–69. SéguinCA BernierSM TNFα suppresses link protein and type II collagen expression in chondrocytes: role of MEK1/2 and NF-κB signaling pathways J Cell Physiol 2003 197 356 69 10.1002/jcp.1037114566965 Search in Google Scholar

Li M, Guan H. Noncoding RNAs regulating NF-κB signaling. In: Song E, editor. The long and short non-coding RNAs in cancer biology. Singapore: Springer; 2016, p. 317–36. (Cohen IR, Lajtha NSA, Lambris JD, Paoletti R, series editors. Adv Exp Med Biol., vol. 927). LiM GuanH Noncoding RNAs regulating NF-κB signaling In: SongE editor. The long and short non-coding RNAs in cancer biology Singapore Springer 2016 317 36 (Cohen IR, Lajtha NSA, Lambris JD, Paoletti R, series editors. Adv Exp Med Biol., vol. 927). 10.1007/978-981-10-1498-7_1227376741 Search in Google Scholar

Adli M. IKKα and IKKβ each function to regulate NF-κB activation in the TNF-induced/canonical pathway. PLoS One. 2010; 5:e9428. doi: 10.1371/journal.pone.0009428 AdliM IKKα and IKKβ each function to regulate NF-κB activation in the TNF-induced/canonical pathway PLoS One 2010 5 e9428 10.1371/journal.pone.0009428 282847520195534 Open DOISearch in Google Scholar

Shi J, Zhang C, Yi Z, Lan C. Explore the variation of MMP3, JNK, p38 MAPKs, and autophagy at the early stage of osteoarthritis. IUBMB Life. 2016; 68:293–302. ShiJ ZhangC YiZ LanC Explore the variation of MMP3, JNK, p38 MAPKs, and autophagy at the early stage of osteoarthritis IUBMB Life 2016 68 293 302 10.1002/iub.148226873249 Search in Google Scholar

Jilani AA, Mackworth-Young CG. The role of citrullinated protein antibodies in predicting erosive disease in rheumatoid arthritis: a systematic literature review and meta-analysis. Int J Rheumatol. 2015; 2015:728610. doi: 10.1155/2015/728610 JilaniAA Mackworth-YoungCG The role of citrullinated protein antibodies in predicting erosive disease in rheumatoid arthritis: a systematic literature review and meta-analysis Int J Rheumatol 2015 2015 728610 10.1155/2015/728610 436437025821469 Open DOISearch in Google Scholar

Liang Y, Chen S, Yang Y, Lan C, Zhang G, Ji Z, Lin H. Vasoactive intestinal peptide alleviates osteoarthritis effectively via inhibiting NF-κB signaling pathway. J Biomed Sci. 2018; 25:25. doi: 10.1186/s12929-018-0410-z LiangY ChenS YangY LanC ZhangG JiZ LinH Vasoactive intestinal peptide alleviates osteoarthritis effectively via inhibiting NF-κB signaling pathway J Biomed Sci 2018 25 25 10.1186/s12929-018-0410-z 585109829540226 Open DOISearch in Google Scholar

Chang SH, Mori D, Kobayashi H, Mori Y, Nakamoto H, Okada K, et al. Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway. Nat Commun. 2019; 10:1442. doi: 10.1038/s41467-019-09491-5 ChangSH MoriD KobayashiH MoriY NakamotoH OkadaK Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway Nat Commun 2019 10 1442 10.1038/s41467-019-09491-5 644102030926814 Open DOISearch in Google Scholar

Mazzetti I, Magagnoli G, Paoletti S, Uguccioni M, Olivotto E, Vitellozzi R, et al. A role for chemokines in the induction of chondrocyte phenotype modulation. Arthritis Rheum. 2004; 50:112–22. MazzettiI MagagnoliG PaolettiS UguccioniM OlivottoE VitellozziR A role for chemokines in the induction of chondrocyte phenotype modulation Arthritis Rheum 2004 50 112 22 10.1002/art.1147414730607 Search in Google Scholar

Mahon OR, Kelly DJ, McCarthy GM, Dunne A. Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization. Osteoarthritis Cartilage. 2020; 28:603–12. MahonOR KellyDJ McCarthyGM DunneA Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization Osteoarthritis Cartilage 2020 28 603 12 10.1016/j.joca.2019.10.01031730805 Search in Google Scholar

Grieshaber-Bouyer R, Kämmerer T, Rosshirt N, Nees TA, Koniezke P, Tripel E, et al. Divergent mononuclear cell participation and cytokine release profiles define hip and knee osteoarthritis. J Clin Med. 2019; 8:1631. doi: 10.3390/jcm8101631 Grieshaber-BouyerR KämmererT RosshirtN NeesTA KoniezkeP TripelE Divergent mononuclear cell participation and cytokine release profiles define hip and knee osteoarthritis J Clin Med 2019 8 1631 10.3390/jcm8101631 683273531590365 Open DOISearch in Google Scholar

Kostopoulou F, Malizos KN, Papathanasiou I, Tsezou A. MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes. Arthritis Res Ther. 2015; 17:42. doi: 10.1186/s13075-015-0556-y KostopoulouF MalizosKN PapathanasiouI TsezouA MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes Arthritis Res Ther 2015 17 42 10.1186/s13075-015-0556-y 437584525880168 Open DOISearch in Google Scholar

Tardif G, Hum D, Pelletier JP, Duval N, Martel-Pelletier J. Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord. 2009; 10:148. doi: 10.1186/1471-2474-10-148 TardifG HumD PelletierJP DuvalN Martel-PelletierJ Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes BMC Musculoskelet Disord 2009 10 148 10.1186/1471-2474-10-148 279222019948051 Open DOISearch in Google Scholar

Yatsugi N, Tsukazaki T, Osaki M, Koji T, Yamashita S, Shindo H. Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-myc. J Orthop Sci. 2000; 5:150–6. YatsugiN TsukazakiT OsakiM KojiT YamashitaS ShindoH Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-myc J Orthop Sci 2000 5 150 6 10.1007/s00776005014210982649 Search in Google Scholar

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