[1. Elliot T. Established pyrethroid insecticides. Pestic Sci 1980;11:119-28.10.1002/ps.2780110204]Search in Google Scholar
[2. Tabarean IV, Narahashi T. Potent modulation of tetradotoxinsensitive and tetradotoxin-resistant sodium channels by the type II pyrethroid deltamethrin. J Pharmacol Exp Ther 1998;284:958-65.]Search in Google Scholar
[3. Chandra S, Saxena PN, Gupta SK. In vivo cytogenetic effects of a commercially formulated mixture of cypermethrin and quinalphos in mice. Mutat Res 2005;587:120-5.10.1016/j.mrgentox.2005.08.004]Search in Google Scholar
[4. Chauhan LK, Kumar M, Paul BN, Goel SK, Gupta SK. Cytogenetic effects of commercial formulations of deltamethrin and/or isoproturon on human peripheral lymphocytes and mouse bone marrow cells. Environ Mol Mutagen 2007;48:636-43.10.1002/em.20330]Search in Google Scholar
[5. Celik A, Mazmancı B, Camlıca Y, Comelekoğlu Y, Askın A. Evaluation of cytogenetic effects of k-cyhalothrin in wistar rat bone marrow by gavage administration. Ecotoxicol Environ Saf 2005;61:128-33.10.1016/j.ecoenv.2004.07.009]Search in Google Scholar
[6. Celik A, Mazmancı B, Camlıca Y, Askın A, Comelekoğlu U. Induction of micronuclei by k-cyhalothrin in wistar rat bone marrow and gut epithelial cells. Mutagenesis 2005;20:125-9.10.1093/mutage/gei020]Search in Google Scholar
[7. Giri A, Giri S, Sharma GD. Malathion and fenvalerate induce micronuclei in mouse bone marrow cells. Environ Mol Mutagen 2011;52:607-13.10.1002/em.20649]Search in Google Scholar
[8. Jamil K, Shaik AP, Mahboob M, Krishna D. Effect of organophosphorus and organochlorine pesticides (monocrotophos, chloropyriphos, dimethoate and endosulfan) on human lymphocyte cultures 2004;27:133-44.]Search in Google Scholar
[9. Shukla Y, Yadav A, Arora A. Carcinogenic and cocarcinogenic potential of cypermethrin on mouse skin. Cancer Lett 2002;182:33-41.10.1016/S0304-3835(02)00077-0]Search in Google Scholar
[10. Litchfi eld MH. Toxicity to mammals. In: Leahey JP, editors. The pyrethroid insecticides. London: Taylor & Francis; 1985. p. 99-149.]Search in Google Scholar
[11. Broughton A, Thrasher JD, Madison R. Chronic health effects and immunological alterations associated with exposure to pesticides. Comments Toxicol 1990;4:59-71.]Search in Google Scholar
[12. Holladay SD, Luster MI. Alterations in fetal thymic and liver hematopoietic cells as indicators of exposure to developmental immunotoxicants. Environ Health Perspect 1996;104(Suppl 4):809-13.10.1289/ehp.96104s480914696678880003]Search in Google Scholar
[13. Repetto R, Baliga SS. Pesticide and immunosuppression: the risks to public health. Health Policy Plan 1997;12:97-106.10.1093/heapol/12.2.9710168201]Search in Google Scholar
[14. Kevin Y, Urayama JK, Wiencke B, Chokkalingam AP, Metayer C, Wiemels JL. MDR1 Gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev 2007;16:1172-7.10.1158/1055-9965.EPI-07-000717548681]Search in Google Scholar
[15. Ledirac N, Antherieu S, Uby AD, Caron JC, Rahmani R. Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species. Toxicol Sci 2005;86:444-52.10.1093/toxsci/kfi192]Search in Google Scholar
[16. Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, David A. Stevens DA, Beachy PA. Itraconazole, a commonly used antifungal that inhibits hedgehog pathway activity and cancer growth. Cancer Cell 2010;17:388-99.10.1016/j.ccr.2010.02.027]Search in Google Scholar
[17. Laryea D, Gullbo J, Isaksoon A, Larsson R, Nygren P. Characterization of the cytotoxic properties of the benzimidazole fungicide, benomyl and carbendazim, in human tumor cell lines and primary culture of patient tumor cells. Anticancer Drugs 2010;21:33-4210.1097/CAD.0b013e328330e74e]Search in Google Scholar
[18. Young NS, Issaragrisil S, Ch’en WC, Takaku F. Aplastic anemia in the Orient. Br J Haematol 1986;62:1-6.10.1111/j.1365-2141.1986.tb02893.x]Search in Google Scholar
[19. Muir KR, Chilvers CED, Harriss C, Coulson L, Grainge M, Darbyshire P, Geary CJ, Hows J, Marsh T, Rutherford M, Taylor E, Gordon-Smith EC. The role of occupational and environmental exposures in the aetiology of acquired severe aplastic anaemia: a case control investigation. Br J Haematol 2003;123:906-14.10.1046/j.1365-2141.2003.04718.x]Search in Google Scholar
[20. Fleming LE, Timmeny W. Aplastic anemia and pesticides. An etiologic association? J Occup Med 1993;35:1106-16.]Search in Google Scholar
[21. Botnick LE, Hannon EC, Hellman S. A long lasting proliferative defect in the hematopoietic stem cell compartment following cytotoxic agents. Int J Radiat Oncol Biol Phys 1979;5:1621-5.10.1016/0360-3016(79)90785-5]Search in Google Scholar
[22. Prihartono N, Kriebel D, Woskie S, Thetkhathuek A, Sripaung N, Padungtod C, Kaufman D. Risk of aplastic anemia and pesticide and other chemical exposures. Asia Pac J Public Health 2011;23:369-77.10.1177/101053951140360521490113]Search in Google Scholar
[23. Rugman FP, Cosstic R. Aplastic anemia associated with organochlorine pesticides: Case reports and review of evidence. J Clin Pathol 1990;43:98-101.10.1136/jcp.43.2.985022871690760]Search in Google Scholar
[24. Sanchez-Medal L, Castando JP, Garcia-Rojas F. Insecticides and aplastic anemia. N Engl J Med 1963;269:1365-7.10.1056/NEJM19631219269250814064322]Search in Google Scholar
[25. Wang HH, Grufferman S. Aplastic anemia and occupational pesticide exposure: a case control study. J Occup Med 1981;23:364-6.]Search in Google Scholar
[26. Rau ATK, Coutinho A, Avabratha KS, Rau AR, Warrier RP. Pesticide (endosulfan) levels in the bone marrow of children with hematological malignancies. Indian Pediatr 2012;49:113-7.10.1007/s13312-012-0025-521992855]Search in Google Scholar
[27. Chatterjee S, Basak P ,Chaklader M, Das P, Pereira JA, Chaudhuri S, Law S. Pesticide induced marrow toxicity and effects on marrow cell population and on hematopoietic stroma. Exp Toxicol Pathol 2011 Oct 15. [Epub ahead of print]]Search in Google Scholar
[28. Chatterjee S, Chaklader M, Basak P, Das P, Das M, Pereira JA, Dutta RK, Chaudhuri S, Law S. An animal model of chronic aplastic bone marrow failure following pesticide exposure in mice. Int J Stem Cells 2010;3:54-62.10.15283/ijsc.2010.3.1.54]Search in Google Scholar
[29. Law S, Basu K, Banerjee S, Begum B, Chaudhuri S. Cord blood derived plasma factor (CBPF) potentiated the low cytokinetic and immunokinetic profi le of bone marrow cells in pesticide victims suffering from Acquired Aplastic Anaemia (AAA): an 2006;35:209-25.]Search in Google Scholar
[30. Nusslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980;287:795-801.10.1038/287795a0]Search in Google Scholar
[31. Roy S, Ingham PW. Hedgehogs tryst with the cell cycle. J Cell Sci 2002;115:4393-97.10.1242/jcs.00158]Search in Google Scholar
[32. Kalderon D. Transducing the hedgehog signal. Cell 2000;103:371-4.10.1016/S0092-8674(00)00129-X]Search in Google Scholar
[33. Taipale J, Cooper MK, Maiti T, Beachy PA. Patched acts catalytically to suppress the activity of Smoothened. Nature 2002;418:892-7.10.1038/nature00989]Search in Google Scholar
[34. Adolphe C, Hetherington R, Ellis T, Wainwright B. Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res 2006;66:2081-8.10.1158/0008-5472.CAN-05-2146]Search in Google Scholar
[35. Lee J, Platt KA, Censullo P, Ruiz I, Altaba A. Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 1997;124:2537-52.10.1242/dev.124.13.2537]Search in Google Scholar
[36. Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996;86:897-906.10.1016/S0092-8674(00)80165-8]Search in Google Scholar
[37. Farrington SM, Belaoussoff M, Baron MH. Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev 1997;62:197-211.10.1016/S0925-4773(97)00664-3]Search in Google Scholar
[38. Dyer MA, Farrington SM, Mohn D, Munday JR, Baron MH. Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development 2001;128:1717-30.10.1242/dev.128.10.171711311154]Search in Google Scholar
[39. Cridland SO, Keys JR, Papathanasiou P, Perkins AC. Indian hedgehog supports defi nitive erythropoiesis. Blood Cells Mol Dis 2009;43:149-55.10.1016/j.bcmd.2009.04.00419443245]Search in Google Scholar
[40. Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstong SA, Ghilardi N, Gould S, Sauvage FJ, McMahon AP, Gilliland DG. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell 2009;4:559-67.10.1016/j.stem.2009.03.016306532319497284]Search in Google Scholar
[41. Gao J, Graves S,Koch U, Liu S, Jankovic V,Buonamici S, Andaloussi AE, Nimer SD, Kee BL, Taichman R, Radtke F, Aifantis I. Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell 2009;4:548-58.10.1016/j.stem.2009.03.015291468819497283]Search in Google Scholar
[42. Merchant AA, Matsui W. Smoothening the controversial role of hedgehog in hematopoiesis. Cell Stem Cell 2009;4:470-1.10.1016/j.stem.2009.05.006423409919497273]Search in Google Scholar
[43. Mar BG, Amakye D, Aifantis I, Buonamici S. The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis. Leukemia 2011;25:1665-73.10.1038/leu.2011.143431048021660044]Search in Google Scholar
[44. Trowbridge JJ, Scott MP, Bhatia. M. Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proc Natl Acad Sci USA 2006;103:14134-9.10.1073/pnas.0604568103159992416968775]Search in Google Scholar
[45. Dierks C, Beigi R, Guo GR, Zirlik K, Stegert MR, Manley P, Trussell C, Graeff AS, Landwerlin K, Veelken H, Warmuth M. Expansion of Bcr-Abl-Positive leukemic stem cells is dependent on Hedgehog pathway activation. Cancer Cell 2008;14:238-49.10.1016/j.ccr.2008.08.00318772113]Search in Google Scholar
[46. Zhao C, Chen A, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, Munchhof M, Van Arsdale T, Beachy PA, Reya T. Hedgehog signaling is essential for maintenance of cancer stem cells in myeloid leukemia. Nature 2009;458:776-9.10.1038/nature07737294623119169242]Search in Google Scholar
[47. Bhardwaj G, Murdoch B, Wu D, Baker DP, Williams KP, Chadwick K, Ling LE, Karanu FN, Bhatia M. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nature Immunol 2001;2:172-80.10.1038/8428211175816]Search in Google Scholar
[48. Detmer K, Thompson AJ, Garner RE, Walker AN, Gaffi eld W, Dannaw H. Hedgehog signaling and cell cycle control in differentiating erythroid progenitors. Blood Cells Mol Dis 2005;34:60-70.10.1016/j.bcmd.2004.08.02615607701]Search in Google Scholar
[49. Merchant A, Joseph G, Wang O, Brennan S, Matsui W. Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors. Blood 2010;115:2391-6.10.1182/blood-2009-09-241703284589720107231]Search in Google Scholar
[50. Sengupta A, Banerjee D, Chandra S, Banerji SK, Ghosh R, Roy R, Banerjee S. Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression. Leukemia 2007;21:949-55.10.1038/sj.leu.240465717361218]Search in Google Scholar
[51. Bai L-Y, Chiu C-F, Lin C-W, Hsu N-Y, Lin C-L, Lo W-J, Kao M-C. Differential expression of Sonic hedgehog and Gli1 in hematological malignancies. Leukemia 2008;22:226-8.10.1038/sj.leu.240497817928882]Search in Google Scholar
[52. Chatterjee S, Basak P, Das M, Das P, Pereira JA, Dutta RK, Chaklader M, Chaudhuri S, Law S. Kinetic impairment of haemopoietic stem cells in experimentally induced leukemia and aplastic anemia: an inverse correlation. J Stem Cells 2009;4:179-89.]Search in Google Scholar
[53. Queiroz MLS, da Rocha MC, Torello CO, Queiroz JS, Bincoletto C, Morgano MA, Romano MR, Paredes-Gamero EJ, Barbosa CMV, Calgarotto AK. Chlorella vulgaris restores bone marrow cellularity and cytokine production in leadexposed mice. Food Chem Toxicol 2011;49:2934-41.10.1016/j.fct.2011.06.05621820028]Search in Google Scholar
[54. The Niche. Hematopoiesis, no hedgehog needed [displayed 26 July 2012]. Available at http://blogs.nature.com/theniche/2009/06/hematopoiesis_no_hedgehog_need.html]Search in Google Scholar