Are the phosphorus-rich Na₂O–CaO–B₂O₃–SiO₂–P₂O₅ glasses bioactive and what is an influence of doping with manganese oxide?

A series of glasses of the composition 20Na2-O-15CaO-5B₂O₃-5SiO₂-(55 - x) P₂O₅:xMnO₂, was prepared and characterized by XRD, DSC, SEM, and Raman techniques. The samples were later immersed in simulated body fluid (SBF) for checking the potential growth of hydroxyapatite layer (HA). Experiments confirmed that addition of manganese oxide leads to structural changes of the glasses. With increasing content of MnO₂, the surface of the samples became more congenial for improving the growth of HA. The formation of HA layer on the surface of the samples was confirmed just after seven days of immersion. The growth rate of HA has gradually increased with the increase of MnO₂ content.