1. bookVolume 10 (2018): Issue 1 (January 2018)
Journal Details
License
Format
Journal
eISSN
2080-2234
First Published
06 Apr 2009
Publication timeframe
1 time per year
Languages
English
access type Open Access

The effects of Panax ginseng supplementation on growth hormone, cortisol and lactate response to high-intensity resistance exercise

Published Online: 30 Jan 2018
Volume & Issue: Volume 10 (2018) - Issue 1 (January 2018)
Page range: 8 - 14
Received: 23 Oct 2017
Accepted: 02 Jan 2018
Journal Details
License
Format
Journal
eISSN
2080-2234
First Published
06 Apr 2009
Publication timeframe
1 time per year
Languages
English
Summary

Study aim: Growth hormone, cortisol, and lactate play an effective role in regulating and stimulating the muscle building proc­ess. The current study aimed to investigate the impact of Panax ginseng supplementation on growth hormone, cortisol, and lactate response to intense resistance exercise in young female non-athletes. Materials and methods: Ten non-athlete girls participated in this double-blind counter-balanced crossover study. They were assigned to two groups: the ginseng group and the placebo group. In two 4-week periods, they received the supplement and the placebo. In the first four weeks, 5 participants received ginseng (100 mg daily) and 5 others received placebo (maltodextrin). At the end of the 4 weeks, blood samples (5 ml) were taken to measure blood levels of the factors. Afterwards, the resistance exercise protocol was implemented, and immediately after that blood samples were taken. In the second four-week period, the five participants who had taken ginseng received placebo, and the five subjects who had received placebo took ginseng. The same tests were administered again. Results: The results showed that except for cortisol in the ginseng group, there were significant pre - to post-exercise changes for all 3 indicators in both groups. No significant difference was observed in pre - to post-exercise changes in the levels of GH (p = 0.71), cortisol (p = 0.34), or lactate (p = 0.90) between groups. Conclusions: 100 mg ginseng consumption daily for 4 weeks does not have an impact on the response of GH, cortisol, or lac­tate to high-intensity resistance exercise in young female non-athletes.

Keywords

1. Arzeghar M., A. Hematfar, S.M. Naghibzadeh, J. Rashna­vadinejad (2014) Effect of panax ginseng on indicators of physiological, blood biochemical, and body composition during strength training of male power lifting athletes. IJSS, 4(4): 380-385.Search in Google Scholar

2. Bahrke M.S., W.P. Morgan (1994) Evaluation of the ergogenic properties of ginseng. Sports Med., 18(4): 229-248.Search in Google Scholar

3. Bahrke M.S., W.P. Morgan, A. Stegner (2009) Is ginseng an ergogenic aid? Int. J. Sport Nutr. Exerc. Metab., 19(3): 298-322.10.1123/ijsnem.19.3.298Search in Google Scholar

4. Borst S.E., D.V. De Hoyos, L. Garzarella, K. Vincent, B.H. Pollock, D.T. Lowenthal, M.L. Pollock (2001) Ef­fects of resistance training on insulin-like growth fac­tor-I and IGF binding proteins. Med. Sci. Sports Exerc., 33(4): 648-653.10.1097/00005768-200104000-00021Search in Google Scholar

5. Brekhmam I., I. Dardymov (1969) Pharmacological in­vestigations of glycosides from ginseng and Eleuthero­coccus. Lloydia, 32: 46-51.Search in Google Scholar

6. Briskin D.P. (2000) Medicinal plants and phytomedi­cines. Linking plant biochemistry and physiology to hu­man health. Plant Physiol., 124(2): 507-514.Search in Google Scholar

7. Brzycki M. (1993) Strength testing - predicting a one-rep max from reps-to-fatigue. J. Phys. Educ. Recreat. Dance, 64(1): 88-90.10.1080/07303084.1993.10606684Search in Google Scholar

8. Chong S., V. Oberholzer (1988) Ginseng--is there a use in clinical medicine? Postgrad. Med. J., 64(757): 841-846.Search in Google Scholar

9. Craig B.W., H.Y. Kang (1994) Growth Hormone Release Following Single Versus Multiple Sets of Back Squats: Total Work Versus Power. J. Strength Cond. Res., 8(4): 270-275.Search in Google Scholar

10. Cumming D.C., L. Brunsting 3rd, G. Strich, A.L. Ries, R.W. Rebar (1986) Reproductive hormone increases in response to acute exercise in men. Med. Sci. Sports Ex­erc., 18(4): 369-373.10.1249/00005768-198608000-00001Search in Google Scholar

11. Durand R.J., V.D. Castracane, D.B. Hollander, J.L. Tryniecki, M.M. Bamman, S. O’Neal, E.P. Hebert, R.R. Kraemer (2003) Hormonal responses from concen­tric and eccentric muscle contractions. Med. Sci. Sports Exerc., 35(6): 937-943.10.1249/01.MSS.0000069522.38141.0BSearch in Google Scholar

12. Ehrnborg C., K. Lange, R. Dall, J. Christiansen, P.-A. Lundberg, R. Baxter, M.A. Boroujerdi, B.A. Bengtsson, M.L. Healey, C. Pentecost, S. Longobardi, R. Napoli, T. Rosén (2003) The growth hormone/insulin-like growth factor-I axis hormones and bone markers in elite athletes i n response to a maximum exercise test. J. Clin. Endocrinol. Metab., 88(1): 394-401.10.1210/jc.2002-020037Search in Google Scholar

13. Engels H.-J., J.C. Wirth (1997) No ergogenic effects of ginseng (Panax ginseng CA Meyer) during graded maximal aerobic exercise. J. Am. Diet. Assoc., 97(10): 1110-1115.Search in Google Scholar

14. Gaffney B., H. Hügel, P. Rich (2001) Panax ginseng and Eleutherococcus senticosus may exaggerate an already existing biphasic response to stress via inhibition of en­zymes which limit the binding of stress hormones to their receptors. Med. Hypotheses, 56(5): 567-572.10.1054/mehy.2000.1163Search in Google Scholar

15. Gaffney B.T., H.M. Hügel, P.A. Rich (2001) The effects of Eleutherococcus senticosus and Panax ginseng on ste­roidal hormone indices of stress and lymphocyte subset numbers in endurance athletes. Life Sci., 70(4): 431-442. 10.1016/S0024-3205(01)01394-7Search in Google Scholar

16. Godfrey R.J., Z. Madgwick, G.P. Whyte (2003) The exercise-induced growth hormone response in athletes. Sports Med., 33(8): 599-613.10.2165/00007256-200333080-0000512797841Search in Google Scholar

17. Goto K., N. Ishii, K. Takamatsu (2004) Growth hormone response to training regimen with combined high-and low-intensity resistance exercises. Int. J. Sport Health Sci., 2: 111-118.Search in Google Scholar

18. Goulet E.D., A. Hassaine, I.J. Dionne, P. Gaudreau, A. Khalil, T. Fulop, B. Shatenstein, D. Tessier, J.A. Mo­rais (2009) Frailty in the elderly is associated with insulin resistance of glucose metabolism in the postabsorptive state only in the presence of increased abdominal fat. Exp. Geront., 44(11): 740-744.10.1016/j.exger.2009.08.00819723576Search in Google Scholar

19. Hallstrom C., S. Fulder, M. Carruthers (1978) Effects of ginseng on the performance of nurses on night duty. Am. J. Chin. Med., 6(04): 277-282.10.1142/S014729177800037XSearch in Google Scholar

20. Hansen S., T. Kvorning, M. Kjaer, G. Sjøgaard (2001) The effect of short‐term strength training on human skeletal muscle: the importance of physiologically el­evated hormone levels. Scand. J. Med. Sci. Sports, 11(6): 347-354.10.1034/j.1600-0838.2001.110606.xSearch in Google Scholar

21. Hsu C.-C., M.-C. Ho, L.-C. Lin, B. Su, M.-C. Hsu (2005) American ginseng supplementation attenuates creatine kinase level induced by submaximal exercise in human beings. World J. Gastroenterol., 11(34): 5327.Search in Google Scholar

22. Kang H.Y., S.H. Kim, W.J. Lee, H.K. Byrne (2002) Ef­fects of ginseng ingestion on growth hormone, testoster­one, cortisol, and insulin-like growth factor 1 responses to acute resistance exercise. J. Strength Cond. Res., 16(2): 179-183.10.1519/00124278-200205000-00003Search in Google Scholar

23. Kraemer W.J., S.E. Gordon, S.J. Fleck, L. Marchitelli, R. Mello, J.E. Dziados, K. Friedl, E. Harman, C. Maresh, A.C. Fry (1991) Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females. Int. J. Sports Med., 12(02): 228-235.10.1055/s-2007-1024673Search in Google Scholar

24. Kraemer W.J., K. Häkkinen, R.U. Newton, B.C. Nindl, J.S. Volek, M. McCormick, L.A. Gotshalk, S.E. Gordon, S.J. Fleck, W.W. Campbell, M. Putukian, W.J. Evans (1999) Effects of heavy-resistance training on hormon­al response patterns in younger vs. older men. J. Appl. Physiol., 87(3): 982-992.10.1152/jappl.1999.87.3.982Search in Google Scholar

25. Kraemer W.J., L. Marchitelli, S.E. Gordon, E. Har­man, J.E. Dziados, R. Mello, P. Frykman, D. McCurry, S.J. Fleck (1990) Hormonal and growth factor responses to heavy resistance exercise protocols. J. Appl. Physiol., 69(4): 1442-1450.10.1152/jappl.1990.69.4.1442Search in Google Scholar

26. Lee N.-H., C.-G. Son (2011) Systematic review of ran­domized controlled trials evaluating the efficacy and safety of ginseng. J. Acupunct. Meridian Stud., 4(2): 85-97.Search in Google Scholar

27. McNaughton L., G. Egan, G. Caelli (1989) A compari­son of Chinese and Russian ginseng as ergogenic aids to improve various facets of physical fitness. Int. Clin. Nutr. Rev., 9(1): 32-35.Search in Google Scholar

28. Morris A.C., I. Jacobs, T.M. McLellan, A. Klugerman, L.C. Wang, J. Zamecnik (1996) No ergogenic effect of ginseng ingestion. Int. J. Sport Nutr., 6(3): 263-271.10.1123/ijsn.6.3.263Search in Google Scholar

29. Onanong Kulaputana M. (2007) Ginseng supplemen­tation does not change lactate threshold and physicalperformances in physically active Thai men. J. Med. As­soc. Thai., 90(6): 1172-1179.Search in Google Scholar

30. Ping F.W.C., C.C. Keong, A. Bandyopadhyay (2011) Ef­fects of acute supplementation of Panax ginseng on en­durance running in a hot & humid environment. Indian J. Med. Res., 133(1): 96.Search in Google Scholar

31. Stone M.H. (1995) Literature review: Human Growth Hormone: Physiological Functions and Ergogenic Effi­cacy. Strength Cond. J., 17(4): 72-74.10.1519/1073-6840(1995)017<0072:HGHPFA>2.3.CO;2Search in Google Scholar

32. Takamura Y., Y. Makanae, S. Ato, N. Yoshii, K. Ki­do, M. Nomura, A. Uchiyama, N. Shiozawa, S. Fujita (2016) Panaxatriol derived from ginseng augments resist­ance exercised-induced protein synthesis via mTORC1 signaling in rat skeletal muscle. Nutr. Res., 36(11): 1193-1201.10.1016/j.nutres.2016.09.002Search in Google Scholar

33. Thompson P.D., B.A. Franklin, G.J. Balady, S.N. Blair, D. Corrado, N.M. Estes, J.E. Fulton, N.F. Gordon, W.L. Haskell, M.S. Link, B.J. Maron, M.A. Mittleman, A. Pelliccia, N.K. Wenger, S.N. Willich, F. Costa (2007) Exercise and acute cardiovascular events. Circulation, 115(17): 2358-2368.Search in Google Scholar

34. Vogler B., M. Pittler, E. Ernst (1999) The efficacy of gin­seng. A systematic review of randomised clinical trials. Eur. J. Clin. Pharmacol., 55(8): 567-575.Search in Google Scholar

35. Wong C.P.F., A. Bandyopadhyay, C.K. Chen (2011) Ef­fects of Panax ginseng supplementation on physiol­ogy responses during endurance performance. J. Mens Health, 8: S78-S80.Search in Google Scholar

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