<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Retinoids are compounds chemically related to vitamin A, which are frequently used in dermatological practice (1). They are characterized by numerous mechanisms of action leading to normalization of keratinocyte proliferation and maturation. They have anti-seborrhoeic, immunomodulatory and anti-inflammatory effects (1, 2). A number of side effects to retinoid treatment have been recorded; one group of such side effects relates to eyes and vision. Dry eye syndrome and blepharoconjunctivitis are the most common side effects, appearing in 20-50 % of patients treated with retinoids. They often contribute to the occurrence of other side-effects such as eye discomfort and contact lens intolerance. Due to the widespread use in clinical practice, the adverse effects, including ocular side effects, should be studied. To confirm the variety of adverse effects of retinoids, several case reports of rare side-effects are presented.</p></abstract>

Retinoids are compounds chemically related to vitamin A, which are frequently used in dermatological practice (1). They are characterized by numerous mechanisms of action leading to normalization of keratinocyte proliferation and maturation. They have anti-seborrhoeic, immunomodulatory and anti-inflammatory effects (1, 2). A number of side effects to retinoid treatment have been recorded; one group of such side effects relates to eyes and vision. Dry eye syndrome and blepharoconjunctivitis are the most common side effects, appearing in 20-50 % of patients treated with retinoids. They often contribute to the occurrence of other side-effects such as eye discomfort and contact lens intolerance. Due to the widespread use in clinical practice, the adverse effects, including ocular side effects, should be studied. To confirm the variety of adverse effects of retinoids, several case reports of rare side-effects are presented.

Side effects of retinoid therapy on the quality of vision

Department of Dermatology, Medical University of Silesia 40-027, Katowice,

Provincial Specialized Hospital, MEGREZ Sp. z o. o. 43-100 Tychy,

Andrzej Mielęcki Silesian Independent, Public Clinical Hospital in Katowice, Department of Dermatology, 40-027 Katowice,

Department of Environmental Health, School of Public Health in Bytom, Medical University of Silesia School of Public Health in Bytom, 41-902 Bytom,

Acta Pharmaceutica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Side effects of retinoid therapy on the quality of vision"}

Retinoids are compounds chemically related to vitamin A, which are frequently used in dermatological practice (1). They are characterized by numerous...

Side effects of retinoid therapy on the quality of vision

Published Online: Oct 15, 2016

Page range: 471 - 478

Accepted: Apr 18, 2016

DOI: https://doi.org/10.1515/acph-2016-0039

Keywords
retinoids, isotretinoin, adverse effects, eyes, acne

© by Beata Bergler-Czop

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Side effects of retinoid therapy on the quality of vision

Published Online: Oct 15, 2016

Page range: 471 - 478

Accepted: Apr 18, 2016

DOI: https://doi.org/10.1515/acph-2016-0039

Keywordsretinoids, isotretinoin, adverse effects, eyes, acne

© by Beata Bergler-Czop

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
retinoids, isotretinoin, adverse effects, eyes, acne