Formerly: Beiträge zur Tabakforschung International

Contributions to Tobacco & Nicotine Research

Contributions to Tob. Res. ONL

<abstract><title style='display:none'>Abstract</title> For the estimation of the different methods used for obtaining and fractioning tobacco tars, it is necessary to consider the reactivity of the For the estimation of the different methods used for obtaining and fractioning tobacco tars, it is necessary to consider the reactivity of the individual components and the characteristic action of the entire product. For analytical and biological tests a product is required which has not undergone any important chemical or biochemical changes. It is shown that this important condition has mostly been neglected. The changes likely to occur in the tar during the different smoking and preparation procedures are discussed. It is pointed out that a great number of compounds have been described, in particular in the more recent literature, which are eager to react with other substances and which, being constituents of tobacco smoke, might be responsible for such chemical changes.Several tars were submitted to a limited ageing under different physical conditions. Such simple tests demonstrate the important changes taking place in the original tar when submitted to temperature, light and air and if concentrations in the solvent are too high. On the basis of such general reflections it is concluded that the biological tests described until now require reexamination and that it is necessary to develop and apply such procedures, both for the production and the preparation of tobacco tars, which prevent the formation of artefacts</abstract>

Abstract

Medizinische Forschungsanstalt der Max-Planck-Gesellschaft, Göttingen, Germany

<article-title>Fundamental Reflections on the Chemical Composition of Tobacco Smoke and its Reactivity Products / Grundsätzliche Überlegungen zur chemischen Zusammensetzung des Tabakrauches und seiner Abscheidungsprodukte</article-title>

Fundamental Reflections on the Chemical Composition of Tobacco Smoke and its Reactivity Products / Grundsätzliche Überlegungen zur chemischen Zusammensetzung des Tabakrauches und seiner Abscheidungsprodukte

<abstract><title style='display:none'>SUMMARY</title> In our opinion mechanical smoke collection traps do not make sufficient allowance for the particular chemical and physico chemical properties of tobacco tar and its constituents, and, therefore, do not produce the tar in its original state. For this reason a new apparatus has been designed which compared to other processes makes it possible to collect the tobacco smoke in a solvent. Our experience has shown that this is the only practicable method of producing a tobacco tar which as far as possible remains unchanged by chemical reactions and is suitable for biological tests. The tobacco smoke is washed out by the solvent in a wash bottle and a suitably diluted tar solution is obtained which is drawn off intermittently. The specially designed smoking apparatus is separately mounted on top so that the smoke passes into the wash bottle by the shortest possible route. The entire machine is built into a framework of angle iron and is mounted on vibration dampers to eliminate oscillation. It enables a large number of cigarettes to be smoked in a very short time</abstract>

SUMMARY

<article-title>A New Apparatus for the Collection of Tobacco Smoke for Producing Native Tobacco Tar / Eine neue maschinelle Abrauch- und Rauchabscheidungsapparatur zur Gewinnung von „nativem“ Tabakteer</article-title>

A New Apparatus for the Collection of Tobacco Smoke for Producing Native Tobacco Tar / Eine neue maschinelle Abrauch- und Rauchabscheidungsapparatur zur Gewinnung von „nativem“ Tabakteer

Wissenschaftliche Abteilung der British American Tobacco Co. (C. E.) GmbH, Hamburg, Germany

<article-title>Microphotography of Histology and Anatomy of Tobacco / Mikroaufnahmen zur Histologie und Anatomie des Tabaks</article-title>

Microphotography of Histology and Anatomy of Tobacco / Mikroaufnahmen zur Histologie und Anatomie des Tabaks

<abstract><title style='display:none'>Abstract</title> Microscopic examinations suggest that the trichomes, owing to their dew condensing qualities, when moist, and to their stickiness, when dry, are responsible for the trapping and fixing of the conidia. They can therefore be regarded to be the basis of the epidemic appearance of Peronospora tabacina Adam</abstract>

Wissenschaftliche Abteilung der British American Tobacco Co. (E.C.) GmbH, Hamburg, Germany

<article-title>Fixing Mechanism of Conidiophores of Peronospora Tabacina Adam / Der Haftmechanismus der Konidiosporen von Peronospora Tabacina Adam</article-title>

Fixing Mechanism of Conidiophores of Peronospora Tabacina Adam / Der Haftmechanismus der Konidiosporen von Peronospora Tabacina Adam

<abstract><title style='display:none'>Abstract</title> Following an introductory survey of the literature concerning the induction of bronchial cancer in laboratory animals after exposure to cigarette smoke or intrapulmonary application of smoke condensates, a method is described for a single pertracheal instillation of smoke condensate into peripheral areas of the bronchial system of rats. Histological examination of the lungs showed the appearance of intrapulmonary foreign body granulomas and squamous cell metaplasia of the bronchial epithelium. According to the experiences of oncology, the lack of neoplastic reactions in spite of the 10 months’ duration of the experiments might be explained by the small dosages which had to be limited due to the applied technique. As far as we know at present, the possible maximum carcinogenic potency of the smoke condensates applied is only about 1/100 of those dosages of pure carcinogens which, according to the literature, are sufficient to cause bronchial carcinoma in rats. For technical reasons it seems recommendable for further in vivo studies with lung tissue to use concentrated tobacco smoke condensate or its fractions.</abstract>

Pathologisches Institut der Universität Hamburg, Germany

<article-title>Examination of the Influences of Tobacco Smoke Condensate on the Lung Tissue of Rats / Tierexperimentelle Lungengewebsveränderungen durch Tabakrauchkondensat</article-title>

Examination of the Influences of Tobacco Smoke Condensate on the Lung Tissue of Rats / Tierexperimentelle Lungengewebsveränderungen durch Tabakrauchkondensat

<abstract><title style='display:none'>Abstract</title> A smoking machine has been built which, while being as simple as possible is designed to carry out almost every conceivable function that might be required of a laboratory smoking machine and which allows the operator complete freedom of choice on every aspect of his smoking conditions</abstract>

Research and Instrument Department Cigarette Components Ltd. London, England

<article-title>A New Automated Smoking Machine Allowing to Examine Various Smoking Conditions / Eine neue automatische Rauchmaschine zur Einstellung auf die verschiedensten Abrauchbedingungen</article-title>

A New Automated Smoking Machine Allowing to Examine Various Smoking Conditions / Eine neue automatische Rauchmaschine zur Einstellung auf die verschiedensten Abrauchbedingungen

<abstract><title style='display:none'>Abstract</title> An apparatus for automatic weight selection of cigarettes or filter rods has been constructed, which is specially suited for the preparation of working samples for chemical and physical tests</abstract>

<article-title>An Apparatus for Automatic Weight Selection of Cigarettes / Eine Sortierwaage zur automatischen Selektion von Cigaretten</article-title>

An Apparatus for Automatic Weight Selection of Cigarettes / Eine Sortierwaage zur automatischen Selektion von Cigaretten

<abstract xml:lang="de"><title style='display:none'>Abstract</title> 4. Vorschrift für die Bestimmung des Nikotins im Tabak, im Tabakrauchkondensat und in Filtern 4.1 Bestimmung des Nikotins im Tabak 4.2 Bestimmung des Nikotins im Tabakrauchkondensat 4.3 Bestimmung des Nikotins in Cigarettenfiltern</abstract>

Wissenschaftliche Forschungsstelle im Verband der Cigarettenindustrie, Bonn, Germany

<article-title>Standardized regulations for the analysis of tobacco and tobacco smoke / Einheitliche Vorschriften für die Analyse von Tabak und Tabakrauch</article-title>

Standardized regulations for the analysis of tobacco and tobacco smoke / Einheitliche Vorschriften für die Analyse von Tabak und Tabakrauch

Contributions to Tobacco and Nicotine Research is covered by the following services: <ul> <li> Baidu Scholar </li> <li> Biobase </li> <li> CABI (over 50 subsections) </li> <li> Chemical Abstracts Service (CAS) - CAplus </li> <li> Chemical Abstracts Service (CAS) - SciFinder </li> <li> CNKI Scholar (China National Knowledge Infrastructure) </li> <li> CNPIEC - cnpLINKer </li> <li> Dimensions </li> <li> DOAJ (Directory of Open Access Journals) </li> <li> EBSCO </li> <li> ExLibris </li> <li> Genamics JournalSeek </li> <li> Google Scholar </li> <li> Japan Science and Technology Agency (JST) </li> <li> J-Gate </li> <li> JournalGuide </li> <li> JournalTOCs </li> <li> KESLI-NDSL (Korean National Discovery for Science Leaders) </li> <li> MyScienceWork </li> <li> Naver Academic </li> <li> Naviga (Softweco) </li> <li> ProQuest </li> <li> Publons </li> <li> QOAM (Quality Open Access Market) </li> <li> ReadCube </li> <li> SCImago (SJR) </li> <li> SCOPUS </li> <li> Semantic Scholar </li> <li> TDNet </li> <li> Ulrich's Periodicals Directory/ulrichsweb </li> <li> WanFang Data </li> <li> WorldCat (OCLC) </li> <li> X-MOL </li> </ul>

Contributions to Tobacco and Nicotine Research ist in den folgenden Services indiziert: <ul> <li> Baidu Scholar </li> <li> Biobase </li> <li> CABI (over 50 subsections) </li> <li> Chemical Abstracts Service (CAS) - CAplus </li> <li> Chemical Abstracts Service (CAS) - SciFinder </li> <li> CNKI Scholar (China National Knowledge Infrastructure) </li> <li> CNPIEC - cnpLINKer </li> <li> Dimensions </li> <li> DOAJ (Directory of Open Access Journals) </li> <li> EBSCO </li> <li> ExLibris </li> <li> Genamics JournalSeek </li> <li> Google Scholar </li> <li> Japan Science and Technology Agency (JST) </li> <li> J-Gate </li> <li> JournalGuide </li> <li> JournalTOCs </li> <li> KESLI-NDSL (Korean National Discovery for Science Leaders) </li> <li> MyScienceWork </li> <li> Naver Academic </li> <li> Naviga (Softweco) </li> <li> ProQuest </li> <li> Publons </li> <li> QOAM (Quality Open Access Market) </li> <li> ReadCube </li> <li> SCImago (SJR) </li> <li> SCOPUS </li> <li> Semantic Scholar </li> <li> TDNet </li> <li> Ulrich's Periodicals Directory/ulrichsweb </li> <li> WanFang Data </li> <li> WorldCat (OCLC) </li> <li> X-MOL </li> </ul>

Advisory Board　　　 Bernhard Eitzinger, delfortgroup AG, Traun, Austria Ernest Groman, University of Vienna, Vienna, Austria Daniel Heck, HeckTox LLC, Greensboro, NC, USA Anne Fisher, University of Kentucky, Lexington, KY, USA Xie Jianping, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China Hubert Klus, St. Pölten, Austria John H. Lauterbach, Lauterbach &amp; Associates LLC, Macon, GA, USA Ramsey Lewis, North Carolina State University, Raleigh, NC, USA Chuan Liu, Southampton, UK Michael W. Ogden, Ogden Ology, LLC, Lewisville, NC, USA Thilo Paschke, Japan Tobacco International SA, Geneva, Switzerland Stephen W. Purkis, Bristol, UK Elmar Richter, Walther Straub Institute, Department of Toxicology, Ludwig-Maximilians-University, Munich, Germany Wolfram Roeper, Hamburg, Germany Wolfgang Trinkies, Bayreuth, Germany　 Andreas Zemann, Leopold-Franzens-University of Innsbruck, Innsbruck, Austria Editors Wolf-Dieter Heller Gerhard Scherer Editorial Office Barbara Boenke Brigitte Müller Anja Thielen Contact <A href="mailto:editors@beitraege-bti.de">editors@beitraege-bti.de</A> Publisher De Gruyter Poland Bogumiła Zuga 32A Str. 01-811 Warsaw, Poland T: +48 22 701 50 15

<DIV align=left> Please submit your manuscripts to Contributions to Tobacco and Nicotine Research via Editorial Manager system to: <A href="http://www.editorialmanager.com/btfi">www.editorialmanager.com/btfi</A> Open Access License Dieses Werk ist lizenziert unter einer <A href="http://creativecommons.org/licenses/by-nc-sa/4.0/">Creative Commons Namensnennung - Nicht-kommerziell - Weitergabe unter gleichen Bedingungen 4.0 International Lizenz</A> (CC BY-NC-SA 4.0). Autoren, die in dieser Zeitschrift veröffentlichen, behalten alle Urheberrechte und stimmen den Bedingungen der oben genannten CC BY-NC-SA 4.0-Lizenz zu. </DIV>

Please submit your manuscripts to Contributions to Tobacco and Nicotine Research via Editorial Manager system to: <A href="http://www.editorialmanager.com/btfi">www.editorialmanager.com/btfi</A> Open Access Statement The journal is an Open Access journal that allows a free unlimited access to all its contents without any restrictions upon publication to all users. Copyright Policy All publications are licensed under a <A href="http://creativecommons.org/licenses/by-nc-sa/4.0/">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License</A> (CC BY-NC-SA 4.0). Authors who publish with this journal retain all copyrights and agree to the terms of the above-mentioned CC BY-NC-SA 4.0 license. Article Processing Changes To publish in CTNR, authors are not required to pay an Article Processing Charge

Contributions to Tobacco and Nicotine Research (formerly: Beiträge zur Tabakforschung International / Contribution to Tobacco Research International) publishes articles with a focus on tobacco, nicotine, and related consumer products. In addition, all aspects of research on the tobacco plant as well as on product technology and manufacturing are relevant for the Journal. Products of interest comprise (i) combustible tobacco products (cigarettes, cigars, pipes, etc.), (ii) smokeless tobacco (SLT) products (snuff, snus, chewing tobacco, etc.), (iii) tobacco heating products (THP), (iv) electronic cigarettes (e-cigs, w/o nicotine), (v) oral nicotine delivery (OND) products. All scientific investigations on product-related properties (including physical, chemical, biological, and toxicological properties) as well as on the influence on consumers’ behavior and response (including acute and long-term product use patterns and biomarker profiles) are considered for publication. Submissions can be of the following types: original investigations, reviews, short reports commentaries, letters to the editor. Fields covered by the Journal <UL> <LI>Research into the tobacco plant </LI> <UL> <LI>Tobacco plant </LI> <LI>Metabolism </LI> <LI>Cultivation </LI> <LI>Pesticides Biotechnology (Plant pathology, Mycology, Microbiology) </LI> </UL></UL> <UL> <LI>Manufacture of tobacco products </LI> <UL> <LI>Processing of tobacco </LI> <LI>Flavor </LI> <LI>Manufacture of cigarettes and other products </LI> <LI>Tobacco and environment </LI> <LI>Chemical engineering including physical chemistry </LI> </UL></UL> <UL> <LI>Analysis and properties of tobacco smoke </LI> <UL> <LI>Physical properties </LI> <LI>Chemical properties </LI> <LI>Combustion studies </LI> <LI>Mainstream/sidestream smoke </LI> <LI>Filter studies </LI> <LI>Special substances </LI> <LI>Analytical methods </LI> <LI>Machine smoking </LI> </UL></UL> <UL> <LI>Tobacco products other than cigarettes </LI> <UL> <LI>Cigars / cigarillos </LI> <LI>Pipe tobacco </LI> <LI>Smokeless tobacco (SLT) products (snuff, snus, chewing tobacco) </LI></UL> <LI>New products </LI> <UL> <LI>Tobacco heating products (THP) </LI> <LI>Electronic cigarettes (e-cigs, w/o nicotine) </LI> <LI>Oral nicotine devices (OND, e.g., nicotine pouches) </LI> </UL></UL> <UL> <LI>Human smoking behavior </LI> <UL> <LI>Biomonitoring </LI> <LI>Consumer behavior </LI></UL></UL> Open Access Statement The journal is an Open Access journal that allows a free unlimited access to all its contents without any restrictions upon publication to all users. Archiving Sciendo archives the contents of this journal in <A href="https://www.portico.org/">Portico</A> - digital long-term preservation service of scholarly books, journals and collections. Plagiarism Policy The editorial board is participating in a growing community of <A href="https://www.crossref.org/services/similarity-check/">Similarity Check System's</A> users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process.

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Contributions to Tobacco & Nicotine Research

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