1. bookTom 24 (2011): Zeszyt 6 (November 2011)
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The Full Bibliography of Dietrich Hoffmann

Data publikacji: 30 Dec 2014
Tom & Zeszyt: Tom 24 (2011) - Zeszyt 6 (November 2011)
Zakres stron: 293 - 313
Informacje o czasopiśmie
License
Format
Czasopismo
eISSN
2719-9509
Pierwsze wydanie
01 Jan 1992
Częstotliwość wydawania
4 razy w roku
Języki
Angielski

1. Hoffmann, D. and E. L. Wynder: Identification of polynuclear aromatic hydrocarbons; 136th National Meeting of the American Chemical Society (Am. Chem. Soc.), Atlantic City, NJ, 1959, No. 16U.Search in Google Scholar

2. Wynder, E. L. and D. Hoffmann: A Study of Tobacco Carcinogenesis. VII. The role of higher polycyclic hydrocar-bons; Cancer 12 (1959) 1079–1086.Search in Google Scholar

3. Wynder, E. L. and D. Hoffmann: The carcinogenicity of benzofluoranthenes; Cancer 12 (1959) 1194–1199.Search in Google Scholar

4. Hoffmann, D. and E. L. Wynder: On the isolation and identification of polycyclic aromatic hydrocarbons; Cancer 13 (1960) 1062–1073.Search in Google Scholar

5. Hoffmann, D. and E. L. Wynder: Short-term determination of carcinogenic aromatic hydrocarbons; Anal. Chem. 32 (1960) 295.Search in Google Scholar

6. Wynder, E. L. and D. Hoffmann: Studies in tobacco carcinogenesis; Proc. American Association for Cancer Research (Am. Assoc. Cancer Res.), 3 (1960) 164.Search in Google Scholar

7. Wynder, E. L. and D. Hoffmann: Some practical aspects of the smoking-cancer problem; New Engl. J. Med. 262 (1960) 540–545.Search in Google Scholar

8. Wynder, E. L. and D. Hoffmann: Tobacco smoking as a cause of cancer; in: Cancer Progress; edited by R. W. Raven, Butter-worths, London, UK, 1960, pp. 77–80.Search in Google Scholar

9. Biekert, E., D. Hoffmann, and L. Enslein: Über 1. 4-Oxazine. IV. Kondensation von 1. 2-Amino-alkoholen mit a-Ketocarbonsäure-estern zu 5. 6-Dihydro-1. 4-oxazinonen-(2); Chem. Ber. 94 (1961) 2778–2785.Search in Google Scholar

10. Biekert, E., D. Hoffmann, and F. J. Meyer: Über 1. 4-Oxazine. I. Darstellung kondensierter 1. 4-Oxazinone-(2) durch Umset- zung von o-Aminophenolen mit -Ketoestern; Chem. Ber. 94 (1961) 1664–1675.Search in Google Scholar

11. Biekert, E., D. Hoffmann, and F. J. Meyer: Über 1. 4-Oxazine. II. Überführung der 1. 4-Benzoxazinone-(2) in Phen-morpholone-(2) und N-substituierte Aminoalkohole; Chem. Ber. 94 (1961) 1676–1682.Search in Google Scholar

12. Hoffmann, D. and E. L. Wynder: Die quantitative Bestim-mung von Phenolen im Tabakrauch; Beitr. Tabakforsch. 1 (1961) 101–106.Search in Google Scholar

13. Wynder, E. L. and D. Hoffmann: Biological and chemical studies of tobacco smoke condensate; Proc. Am. Assoc. Cancer Res. 3 (1961) 280.Search in Google Scholar

14. Wynder, E. L. and D. Hoffmann: Carcinogenicity of di-benzo(a,1)pyrene; Nature 192 (1961) 1092–1093.Search in Google Scholar

15. Wynder, E. L. and D. Hoffmann: Present status of laboratory studies on tobacco carcinogenesis; Acta Pathol. Microbiol. Scand. 52 (1961) 119–132.Search in Google Scholar

16. Wynder, E. L. and D. Hoffmann: A Study of Tobacco Carcinogenesis. VIII. The role of the acidic fractions as promoters; Cancer 14 (1961) 1306–1315.Search in Google Scholar

17. Hoffmann, D. and E. L. Wynder: Analytical and biological studies on gasoline engine exhaust; National Cancer Institute (NCI) Monogr. 9 (1962) 91–116.Search in Google Scholar

18. Hoffmann, D. and E. L. Wynder: A Study of Air Pollution Carcinogenesis. II. The isolation and identification of polynu-clear aromatic hydrocarbons from gasoline engine exhaust condensate; Cancer 15 (1962) 93–102.Search in Google Scholar

19. Wynder, E. L. and D. Hoffmann: A Study of Air Pollution Carcinogenesis. III. Carcinogenic activity of gasoline engine exhaust condensate; Cancer 15 (1962) 103–108.Search in Google Scholar

20. Wynder, E. L. and D. Hoffmann: Air pollution and lung cancer; Proc. Natl. Conf. on Air Pollution, US Public Health Service Publ. No. 1022, 1962, pp. 143–148.Search in Google Scholar

21. Wynder, E. L. and D. Hoffmann: Studies with gaseous and particulate phase of tobacco smoke; 53rd Ann. Meeting Am. Assoc. Cancer Res., 1962, pp. 373.Search in Google Scholar

22. Wynder, E. L. and D. Hoffmann: The role of skin neoplasia in tobacco carcinogenesis; in: Tobacco and Health; edited by G. G. James and R. Rosenthal, Thomas, Springfield, IL, 1962, pp. 61-71.Search in Google Scholar

23. Hoffmann, D., G. Rathkamp, and E. L. Wynder: Comparison of the yields of several selected components in the smoke from different tobacco products; J. Natl. Cancer Inst. 31 (1963) 627-637.Search in Google Scholar

24. Hoffmann, D. and E. L. Wynder: Filtration of phenols from cigarette smoke; J. Natl. Cancer Inst. 30 (1963) 67-84.Search in Google Scholar

25. Hoffmann, D. and E. L. Wynder: Die Filtration von Phenolen aus Cigarettenrauch; Beitr. Tabakforsch. 2 (1963) 51-66.Search in Google Scholar

26. Hoffmann, D. and E. L. Wynder: Studies on Gasoline Engine Exhaust; J. Air Pollut. Control Assoc. 13 (1963) 322-327.10.1080/00022470.1963.10468184Search in Google Scholar

27. Wynder, E. L. and D. Hoffmann: Bioassay s on the carcinoge-nicity of tobacco smoke condensate and air pollutants; Proc. Am. Assoc. Cancer Res. 4 (1963) 73.Search in Google Scholar

28. Wynder, E. L. and D. Hoffmann: Experimental aspects of tobacco carcinogenesis; Dis. Chest 44 (1963) 337-344.Search in Google Scholar

29. Wynder, E. L. and D. Hoffmann: Ein experimenteller Beitrag zur Tabakrauchkanzerogenese [An experimental contribution to the problem of tobacco smoke carcinogenesis]; Dtsch. Med. Wochenschr. 88 (1963) 623-628.Search in Google Scholar

30. Wynder, E. L., H. E. Kaiser, D. A. Goodman, and D. Hoffmann: A method for determining ciliastatic components in cigarette smoke; Cancer 16 (1963) 1222-1225.Search in Google Scholar

31. Hoffmann, D., G. Rathkamp, and E. L. Wynder: Vergleich der Ausbeute an mehreren ausgewählten Komponenten im Rauch verschiedener Tabakerzeugnisse; Beitr. Tabakforsch. 2 (1964) 123-130.Search in Google Scholar

32. Wynder, E. L. and D. Hoffmann: Experimental tobacco carcinogenesis; Adv. Cancer Res. 8 (1964) 249–453.10.1016/S0065-230X(08)60510-2Search in Google Scholar

33. Hoffmann, D., E. Theisz, and E. L. Wynder: Studies on the carcinogenicity of gasoline exhaust; J. Air Pollut. Control Assoc. 15 (1965) 162-165.10.1080/00022470.1965.10468353Search in Google Scholar

34. Wynder, E. L., D. A. Goodman, and D. Hoffmann: Ciliatoxic Components in Cigarette Smoke. II. Carboxylic acids and aldehydes; Cancer 18 (1965) 505-509.Search in Google Scholar

35. Wynder, E. L., D. A. Goodman, and D. Hoffmann: Ciliatoxic Components in Cigarette Smoke. III. In vitro comparison of different smoke components; Cancer 18 (1965) 1652-1658.Search in Google Scholar

36. Wynder, E. L. and D. Hoffmann: Reduction of tumorigenicity of cigarette smoke; JAMA 192 (1965) 88-94.Search in Google Scholar

37. Wynder, E. L. and D. Hoffmann: Some laboratory and epi-demiological aspects of air pollution carcinogenesis; J. Air Pollut. Control Assoc. 15 (1965) 155-159.Search in Google Scholar

38. Wynder, E. L., D. Hoffmann, and O. Auerbach: The role of particulate and volatile components in tobacco carcinogenesis; Proc. Am. Assoc. Cancer Res. 6 (1965) 69.Search in Google Scholar

39. Hoffmann, D. and J. Rubin: Chemical Studies on Tobacco Smoke. I. the Quantitative Determination of Indoles in Cigarette Smoke; Beitr. Tabakforsch. 3 (1966) 409–414.Search in Google Scholar

40. Hoffmann, D. and E. L. Wynder: The tumor initiators in tobacco smoke; Proc. Am. Assoc. Cancer Res. 7 (1966) 32.Search in Google Scholar

41. Hoffmann, D. and E. L. Wynder: Beitrag zur carzinogenen Wirkung von Dibenzopyrenen; Z. Krebsforsch. 68 (1966) 137-149.Search in Google Scholar

42. Rathkamp, G., D. Hoffmann, and E. L. Wynder: Experiments on the reduction of polynuclear aromatic hydrocarbons in cigarette smoke; presented at the 20th Tobacco Chemists’ Research Conference (TCRC), Winston-Salem, NC, 1966, No. 19.Search in Google Scholar

43. Woziwodzki, H. and D. Hoffmann: Free higher fatty acids in tobacco and tobacco smoke; presented at the 20th TCRC, Winston-Salem, NC, 1966, No. 16.Search in Google Scholar

44. Wynder, E. L. and D. Hoffmann: Beziehungen zwischen Epidemiologie und experimenteller Karzinogenese; Münch. Med. Wochenschr. 108 (1966) 1501-1512.Search in Google Scholar

45. Wynder, E. L. and D. Hoffmann: Current concepts of environ-mental cancer research; Med. Clin. North Am. 50 (1966) 631-650.Search in Google Scholar

46. Hoffmann, D., G. Rathkamp, and J. Rubin: Chemical Studies on Tobacco Smoke. II. Comparison of the yields of several selected components in the smoke from five major Turkish tobacco varieties; Food Cosmet. Toxicol. 5 (1967) 37-38.Search in Google Scholar

47. Hoffmann, D. and E. L. Wynder: The reduction of the tumorigenicity of cigarette smoke condensate by addition of sodium nitrate to tobacco; Cancer Res. 27 (1967) 172-174.Search in Google Scholar

48. Rathkamp, G., D. Hoffmann, and E. L. Wynder: Primary and secondary nitrohydrocarbons in cigarette smoke; presented at the 21st TCRC, Durham, NC, 1967, No. 25.Search in Google Scholar

49. Wynder, E. L. and D. Hoffmann: Nutrition and Cancer; in: Prevention of Cancer; edited by R. W. Raven and F. J. C. Roe, Butterworths, London, England, 1967, pp. 11-18.Search in Google Scholar

50. Wynder, E. L. and D. Hoffmann: Tobacco and Tobacco Smoke. Studies in Experimental Carcinogenesis; Academic Press, New York, NY, 1967.Search in Google Scholar

51. Hoffmann, D. and G. Rathkamp:. Chemical Studies on Tobacco Smoke. III. Primary and Secondary Nitroalkanes in Cigarette Smoke; Beitr. Tabakforsch. 4 (1968) 124-134.Search in Google Scholar

52. Hoffmann, D. and G. Rathkamp: Chemical Studies on Tobacco Smoke. V. Quantitative Determination of Chlori-nated Hydrocarbon Insecticides in Cigarette Tobacco and its Smoke; Beitr. Tabakforsch. 4 (1968) 201-214.Search in Google Scholar

53. Hoffmann, D., G. Rathkamp, and H. Woziwodzki: Chemical Studies on Tobacco Smoke. VI. The Determination of Carba-zoles in Cigarette Smoke; Beitr. Tabakforsch. 4 (1968) 253-263.Search in Google Scholar

54. Hoffmann, D. and H. Woziwodzki: Chemical Studies on Tobacco Smoke. IV. The Quantitative Determination of Free Nonvolatile Fatty Acids in Tobacco and Tobacco Smoke; Beitr. Tabakforsch. 4 (1968) 167-175.Search in Google Scholar

55. Hoffmann, D. and E. L. Wynder: Chemical Analysis and Carcinogenic Bioassays of Organic Particulate Pollutants, in: Air Pollution, Vol. II: Analysis, Monitoring and Surveying; edited by A. C. Stern, Academic Press, New York, NY, 1968, pp. 187-247.Search in Google Scholar

56. Hoffmann, D. and E. L. Wynder: Selective reduction of the tumorigenicity of tobacco smoke. Experimental approaches; NCI Monogr. 28 (1968) 151-172.Search in Google Scholar

57. Masuda, Y., D. Hoffmann, and E. L. Wynder: a-Naphthyl-amine and P-naphthy lamine in cigarette smoke; presented at the 22nd TCRC, Richmond, VA, 1968, No. 22.Search in Google Scholar

58. Wynder, E. L. and D. Hoffmann: Experimental tobacco carcinogenesis; Science 162 (1968) 862-871.Search in Google Scholar

59. Wynder, E. L. and D. Hoffmann: Tobacco and Tobacco Smoke; Nature 219 (1968) 661-662.Search in Google Scholar

60. Wynder, E. L. and D. Hoffmann: Selected laboratory methods in tobacco carcinogenesis; in: Methods in Cancer Research, Vol. 4; edited by E. H. Busch, Academic Press, New York, NY, 1968, pp. 3-52.Search in Google Scholar

61. Wynder, E. L. and D. Hoffmann (Editors): Toward a less harmful cigarette; NCI Monograph 28, American Cancer Society, Bethesda, MD, 1968.Search in Google Scholar

62. Wynder, E. L., K. T. Taguchi, V. Baden, and D. Hoffmann: A Study of Tobacco Carcinogenesis. IX. The effect of cigarette smoke on the respiratory tract of mice after passive inhalation; Cancer 21 (1968) 134-153.Search in Google Scholar

63. Hoffmann, D., Y. Masuda, and E. L. Wynder: a-Naphthyl-amine and P-naphthy lamine in cigarette smoke; Nature 221 (1969) 254–256.Search in Google Scholar

64. Hoffmann, D., G. Rathkamp, and S. Nesnow: [Chemical Studies on Tobacco Smoke. VIII.] Quantitative determination of 9-methylcarbazoles in cigarette smoke; Anal. Chem. 41 (1969) 1256-1259.Search in Google Scholar

65. Hoffmann, D., G. Rathkamp, and E. L. Wynder: Chemical Studies on Tobacco Smoke. IX. Quantitative Analysis of Chlorinated Hydrocarbon Insecticides; Beitr. Tabakforsch. 5 (1969) 140-148.Search in Google Scholar

66. Masuda, Y. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. VII.] Quantitative determination of 1-naphthylamine and 2-naphthylamine in cigarette smoke; Anal. Chem. 41 (1969) 650–652.Search in Google Scholar

67. Masuda, Y. and D. Hoffmann: A method for the determination of primary amines of polynuclear aromatic hydrocarbons; J. Chromatogr. Sci. 7 (1969) 694–697.Search in Google Scholar

68. Mazzola, V., G. Rathkamp, and D. Hoffmann: N-Alkyl-indoles, N-alkylcarbazoles, and Dibenzofurans in Cigarette Smoke; presented at the 23rd TCRC, Philadelphia, PA, 1969, No. 22.Search in Google Scholar

69. Radford, E. P., V. R. Hunt, J. B. Little, E. L. Wynder, and D. Hoffmann: Carcinogenicity of Tobacco-smoke Constituents; Science 165 (1969) 312–313.Search in Google Scholar

70. Rathkamp, G. and D. Hoffmann: The inhibition of the pyrosynthesis of several selective smoke components. Experimental findings and theoretical considerations; pre-sented at the 23rd TCRC, Philadelphia, PA, 1969, No. 29.Search in Google Scholar

71. Wynder, E. L. and D. Hoffmann: Current studies on etiology and prevention; in: Lung Cancer: a study of 5,000 Memorial Hospital cases; edited by E. L. Watson, Mosby Company, St. Louis, MO, 1969, pp. 15–34.Search in Google Scholar

72. Wynder, E. L. and D. Hoffmann: A Study of Tobacco Carcinogenesis. X. Tumor promoting activity; Cancer 24 (1969) 289–301.Search in Google Scholar

73. Wynder, E. L. and D. Hoffmann: Bioassays in tobacco carcinogenesis; Prog. Exp. Tumor Res. 11 (1969) 163–193.Search in Google Scholar

74. Hoffmann, D. and V. Mazzola: Chemical Studies on Tobacco Smoke. XI. Dibenzofurans in Cigarette Smoke; Beitr. Tabak-forsch. 5 (1970) 183–188.Search in Google Scholar

75. Hoffmann, D. and G. Rathkamp: [Chemical Studies on Tobacco Smoke. X.] Quantitative determination of 1-alkyl-indoles in cigarette smoke; Anal. Chem. 42 (1970) 366–370.Search in Google Scholar

76. Hoffmann, D. and G. Rathkamp: Chemical Studies on Tobacco Smoke. XII. Quantitative determination of nitroben-zenes in cigarette smoke; Anal. Chem. 42 (1970) 1643–1647.Search in Google Scholar

77. Hoffmann, D. and E. L. Wynder: Chamber development and aerosol dispersion; in: Inhalation Carcinogenesis; edited by H. G. Hanna et al., US Atomic Energy Symp. Ser. 18, Washington, DC, 1970, pp. 173–191.Search in Google Scholar

78. Rathkamp, G. and D. Hoffmann: Fluorenes and fluoranthenes in cigarette smoke; presented at the 24th TCRC, Montreal, Canada, 1970, No. 28.Search in Google Scholar

79. Rathkamp, G. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XIII. Inhibition of the Pyrosyntheses of Several Selective Smoke Constituents; Beitr. Tabakforsch. 5 (1970) 302–306.Search in Google Scholar

80. Wynder, E. L. and D. Hoffmann: the Epidermis and the Respiratory Tract as Bioassay Systems in Tobacco Carcinoge-nesis; Brit. J. Cancer 24 (1970) 574–587.Search in Google Scholar

81. Hoffma nn, D. and J. Vai s: Ana lysis of vola tile N-nitrosami n es in unaged mainstream smoke of cigarettes; presented at the 25th TCRC, Louisville, KY, 1971, No. 23.Search in Google Scholar

82. Hoffmann, D. and E. L. Wynder: A Study of Tobacco Carcinogenesis. XI. Tumor initiators, tumor accelerators, and tumor promoting activity of condensate fractions; Cancer 27 (1971) 848–864.Search in Google Scholar

83. Marquardt, H., A. Bendich, F. S. Phillips, and D. Hoffmann: Binding of [G-3H]-7,12-dimethylbenz(a)anthracene to DNA of normal and of rapidly dividing hepatic cells of rats; Chem. Biol. Interactions 3 (1971) 1–11.Search in Google Scholar

84. Rathkamp, G., T. C. Tso, and D. Hoffmann: On the correlation between various leaf constituents and selected smoke com-pounds; presented at the 25th TCRC, Louisville, KY, 1971, No. 6.Search in Google Scholar

85. Singer, G. and D. Hoffmann: 4-N-Alkylaminophenols in cigarette smoke; presented at the 25th TCRC, Louisville, KY, 1971, No. 22.Search in Google Scholar

86. Wynder, E. L. and D. Hoffmann: Carcinogens in the air; Proc. 24th Ann. Symp. on Fundamental Cancer Research, Houston, TX, Williams & Wilkens, Baltimore, MD, 1971, pp. 118–141.Search in Google Scholar

87. Wynder, E. L., D. Hoffmann, P. Ashwanden, and R. Wachs-muth (Eds.): Less harmful ways of smoking; Proc. of a Workshop of the 2nd World Conf. on Smoking and Health, London, UK, 1971.Search in Google Scholar

88. Brunnemann, K. D. and D. Hoffmann: On the pH of tobacco smoke; presented at the Joint Conference CORESTA and 26th TCRC, Williamsburg, VA, 1972, No. 11.Search in Google Scholar

89. Hoffmann, D.: Benzo[a]pyrene in polluted air; Prev. Med. 1 (1972) 450–451.Search in Google Scholar

90. Hoffmann, D. and G. Rathkamp: [Chemical Studies on Tobacco Smoke. XIV.] Quantitative determination of fluor-enes in cigarette smoke and their formation by pyrosynthe-sis; Anal. Chem. 44 (1972) 899–904.Search in Google Scholar

91. Hoffmann, D., G. Rathkamp, S. Nesnow, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XVI.] Fluoranthenes: Quantitative determination in cigarette smoke, formation by pyrolysis, and tumor initiating activity; J. Natl. Cancer Inst. 49 (1972) 1165–1175.Search in Google Scholar

92. Hoffmann, D. and E. L. Wynder: Chemical Studies on Tobacco Smoke. XV. Chemical Composition and Tumori-genicity of Tobacco Smoke; in: The Chemistry of Tobacco and Tobacco Smoke; edited by I. Schmeltz, Plenum Press, New York, NY, 1972, pp. 123–147.Search in Google Scholar

93. Hoffmann, D. and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XVIII.] Smoke of cigarettes and little cigars: An analytical comparison; Science 178 (1972) 1197–1199.Search in Google Scholar

94. Hoffmann, D. and E. L. Wynder: Respiratory Carcinogens: Their Nature and Precursors; in: Identification and measure-ment of environmental pollutants: proceedings of a sympo-sium; edited by B. Westley, Campbell Printing, Ottawa, Canada, 1972, pp. 9–16.Search in Google Scholar

95. Hoffmann, D. and E. L. Wynder: Selective Reduction of the Tumorigenicity of Tobacco Smoke. II. Experimental approaches; J. Natl. Cancer Inst. 48 (1972) 1855–1868.Search in Google Scholar

96. Rathkamp, G. and D. Hoffmann: Polynuclear aromatic hydrocarbon profile of tobacco smoke; presented at the Joint Conference CORESTA and 26th TCRC, Williamsburg, VA, 1972, No. 09.Search in Google Scholar

97. Wynder, E. L. and D. Hoffmann: Less harmful ways of smoking; J. Natl. Cancer Inst. 48 (1972) 1749–1758.Search in Google Scholar

98. Brunnemann, K. D., D. Hoffmann, and E. L. Wynder: Studies on the inhalability of cigarette and cigar smoke; presented at the 27th TCRC, Winston-Salem, NC, 1973, No. 27.Search in Google Scholar

99. Hecht, S. S., W. E. Bondinell, and D. Hoffmann: Isolation and identification of alkylchrysenes in cigarette smoke; pre-sented at the 27th TCRC, Winston-Salem, NC, 1973, No. 32.Search in Google Scholar

100. Hoffmann, D., G. Rathkamp, K. D. Brunnemann, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXII.] On the profile analysis of tobacco smoke. Sci. Total Environ. 2 (1973) 157–171.Search in Google Scholar

101. Liu, Y. Y. and D. Hoffmann: Maleic hydrazide and volatile hydrazines in cigarette smoke; presented at the 27th TCRC, Winston-Salem, NC, 1973, No. 29.Search in Google Scholar

102. Liu, Y. Y. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XIX. Quantitative chromatographic determination of maleic hydrazide in cigarette smoke; Anal. Chem. 45 (1973) 2270–2273.Search in Google Scholar

103. Rathkamp, D., D. K. Chao, and D. Hoffmann: Analytical studies on nonvolatile N-nitrosamines in cigarette smoke; presented at the 27th TCRC, Winston-Salem, NC, 1973, No. 26.Search in Google Scholar

104. Rathkamp, G., T. C. Tso, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XX. Smoke Analysis of Ciga-rettes Made from Bright Tobaccos Differing in Variety and Stalk Positions; Beitr. Tabakforsch. 7 (1973) 179–189.Search in Google Scholar

105. Schmeltz, I. and D. Hoffmann: Formation of polynuclear aromatic hydrocarbons from combustion of organic matter; in: Carcinogenesis. Polynuclear aromatic hydrocarbons: Chemistry, metabolism, and carcinogenesis; edited by R. I. Freudenthal and P. I. Jones, Raven Press, New York, NY (1973) 225–239.Search in Google Scholar

106. Tso, T. C., G. Rathkamp, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXI. Correlation and Multiple Regression among Selected Cigarette-smoke Constituents and Leaf Characteristics of Bright Tobacco; Beitr. Tabak-forsch. 7 (1973) 190–194.Search in Google Scholar

107. Brunnemann, K. D. and D. Hoffmann: Gas chromatographic determination of ammonia in cigarette and cigar smoke; presented at the 28th TCRC, Raleigh, NC, 1974, No. 53.Search in Google Scholar

108. Brunnemann, K. D. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXIV. A quantitative method for carbon monoxide and carbon dioxide in cigarette and cigar smoke; J. Chromatogr. Sci. 12 (1974) 70–75.Search in Google Scholar

109. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XXV.] The pH of tobacco smoke; Food Cosmet. Toxicol. 12 (1974) 115–124.Search in Google Scholar

110. Hecht, S. S., E. W. Bondinell, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXIX. Chrysene and methyl-chrysenes: Presence in tobacco and carcinogenicity; J. Natl. Cancer Inst. 53 (1974) 1121–1133.Search in Google Scholar

111. Hecht, S. S., R. M. Ornaf, and D. Hoffmann: N-nitroso-alkaloids in tobacco; presented at the 28th TCRC, Raleigh, NC, 1974, No. 36.Search in Google Scholar

112. Hecht, S. S., R. L. Thorne, and D. Hoffmann: Studies of tumor promoters in tobacco smoke; presented at the 28th TCRC, Raleigh, NC, 1974, No. 42.Search in Google Scholar

113. Hoffmann, D., W. E. Bondinell, and E. L. Wynder: Carcino-genicity of methylchrysenes; Science 183 (1974) 215–216.Search in Google Scholar

114. Hoffmann, D., S. S. Hecht, and R. M. Ornaf: Nonvolatile N-nitrosamines in tobacco and tobacco smoke; presented at the CORESTA Symposium Montreux, Suisse, 1974, No. 36.Search in Google Scholar

115. Hoffmann, D., S. S. Hecht, R. M. Ornaf, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXX.] N’-Nitrosonornicotine in tobacco; Science 186 (1974) 265–267.Search in Google Scholar

116. Hoffmann, D., G. Rathkamp, and Y. Y. Liu: Chemical Studies on Tobacco Smoke. XXVI. On the isolation and identification of volatile and non-volatile N-nitrosamines and hydrazines in cigarette smoke; in: N-Nitroso Com-pounds in the Environment, IARC Sci. Publ. 9 (1974) 159–165.Search in Google Scholar

117. Hoffmann, D., L. D. Sanghvi, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXVIII.] Comparative chemical analysis of Indian bidi and American cigarette smoke; Int. J. Cancer 14 (1974) 49–53.Search in Google Scholar

118. Hoffmann, D. and E. L. Wynder: Positive Controls in Environmental Respiratory Carcinogenesis; in: Carcinogene-sis Testing of Chemicals; edited by L. Goldberg, CRC Press, Cleveland, OH, 1974, pp. 35–39.Search in Google Scholar

119. Hu, M. W., W. E. Bondinell, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXIII. Synthesis of carbon-14 labelled myosmine, nornicotine, and N’-nitrosonornicotine; J. Labelled Compd. 10 (1974) 79–88.Search in Google Scholar

120. Kobayashi, N., D. Hoffmann, and E. L. Wynder: A Study of Tobacco Carcinogenesis. XII. Epithelial changes induced in the upper respiratory tracts of Syrian golden hamsters by cigarette smoke; J. Natl. Cancer Inst. 53 (1974) 1085–1089.Search in Google Scholar

121. Liu, Y. Y., I. Schmeltz, and D. Hoffmann: Chemical studies on tobacco smoke [XXVII]. Quantitative analysis of hydra-zine in tobacco and cigarette smoke; Anal. Chem. 46 (1974) 885–889.Search in Google Scholar

122. Schmeltz, I., A. de Paolis, and D. Hoffmann: Quantitative analyses of major phytosterols in tobacco and tobacco smoke; presented at the 28th TCRC, Raleigh, NC, 1974, No. 43.Search in Google Scholar

123. Schmeltz, I., D. Hoffmann, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXXII.] Toxic and Tumorigen-ic Agents in Tobacco Smoke: Analytical Methods and Modes of Origin; Proceedings of the 8th Ann. Conf. on Trace Substances in Environmental Health; edited by D. D. Hem-phill, University of Missouri, Columbia, MO, 1974, pp. 281–295.Search in Google Scholar

124. Wynder, E. L., K. Mabuchi, and D. Hoffmann: Tobacco; in: Cancer Epidemiology and Prevention; edited by D. Schottenfeld, Charles C. Thomas Publ., Springfield, IL, 1974, pp. 102–125.Search in Google Scholar

125. Brunnemann, K. D. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXXIV. Gas chromatographic determination of ammonia in cigarette and cigar smoke; J. Chroma-togr. Sci. 13 (1975) 159–163.Search in Google Scholar

126. Brunnemann, K. D., C. -H. Lee, and D. Hoffmann: A Study of the Precursors and on the Quantitative Analysis of Catechols in Cigarette Smoke; presented at the 29th TCRC, College Park, MD, 1975, No. 46.Search in Google Scholar

127. Hecht, S. S., M. Loy, R. R. Maronpot, and D. Hoffmann: A Study of Chemical Carcinogenesis: Comparative carcinoge-nicity of 5-methylchrysene, benzo(a)pyrene and modified chrysenes. Cancer Lett., 1 (1975) 147–153.Search in Google Scholar

128. Hecht, S. S., R. M. Ornaf, C. B. Chen, D. Hoffmann, and T. C. Tso; On the Origin of N-Nitrosonornicotine in Tobacco; pre-sented at the 29th TCRC, College Park, MD, 1975, No. 34.Search in Google Scholar

129. Hecht, S. S., R. M. Ornaf, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XLI.] Determination of N’-nitrosonornicotine in tobacco by high speed liquid chroma-tography; Anal. Chem. 47 (1975) 2046–2048.Search in Google Scholar

130. Hecht, S. S., R. M. Ornaf, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXXIII. N’-Nitrosonornicotine in tobacco: Analysis of possible contributing factors and biologic implications; J. Natl. Cancer Inst. 54 (1975) 1237–1244.Search in Google Scholar

131. Hecht, S. S., R. L. Thorne, R. R. Maronpot, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XIII. Tumor promoting subfractions of the weakly acidic fraction; J. Natl. Cancer Inst. 55 (1975) 1329–1336.Search in Google Scholar

132. Hoffmann, D., K. D. Brunnemann, G. B. Gori, and E. L. Wynder: On the carcinogenicity of marijuana smoke; Rec. Adv. Phytochem. 9 (1975) 63–81.Search in Google Scholar

133. Hoffmann, D., S. S. Hecht, I. Schmeltz, K. D. Brunnemann, and E. L. Wynder: Chemical Studies on Tobacco Smoke. XLIV. New separation techniques for classes of smoke compounds; Rec. Adv. Tobacco Sci. 1 (1975) 97–122.Search in Google Scholar

134. Hoffmann, D., C. P. Patrianakos, K. D. Brunnemann and G. B. Gori: On the Analysis of Vinyl Chloride in Tobacco Smoke; presented at the 29th TCRC, College Park, MD, 1975, No. 17.Search in Google Scholar

135. Hoffmann, D., R. Raineri, S. S. Hecht, R. R. Maronpot, and E. L. Wynder: A Study of Tobacco Carcinogenesis. XIV. Effect of N’-nitrosonornicotine and N’-nitrosoanabasine in rats; J. Natl. Cancer Inst. 55 (1975) 977–981.Search in Google Scholar

136. Hoffmann, D. and E. L. Wynder: New Separation Techniques for Classes of Smoke Compounds; presented at the 29th TCRC, College Park, MD, 1975, No. 5.Search in Google Scholar

137. Hoffmann, D. and E. L. Wynder: Chemical Studies on Tobacco Smoke. XLIII. The active fractions of cigarette smoke in experimental tobacco carcinogenesis. A review; Tobacco Res. (India) 1 (1975) 88–97.Search in Google Scholar

138. Schmeltz, I., K. D. Brunnemann, D. Hoffmann, and A. Cornell: On the chemistry of cigar smoke: comparisons between experimental little and large cigars; presented at the 29th TCRC, College Park, MD, 1975, No. 41.10.2478/cttr-2013-0405Search in Google Scholar

139. Schmeltz, I., A. de Paolis, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XXXI.] Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion; Beitr. Tabakforsch. 8 (1975) 211–218.Search in Google Scholar

140. Schmeltz, I., D. Hoffmann, and J. Tosk: Naphthalenes in Tobacco Smoke: Analysis and Formation; presented at the 29th TCRC, College Park, MD, 1975, No. 22.Search in Google Scholar

141. Schmeltz, I., D. Hoffmann, and E. L. Wynder: The influence of tobacco smoke on indoor atmospheres. I. An overview; Prev. Med. 4 (1975) 66–82.Search in Google Scholar

142. Wynder, E. L. and D. Hoffmann: The tenth anniversary of the Surgeon General's report on smoking and health. Have we made any progress? Guest Editorial; J. Natl. Cancer Inst. 54 (1975) 533–534.Search in Google Scholar

143. Wynder, E. L., D. Hoffmann, P. Chan, and B. Reddy: Interdisciplinary and Experimental Approaches: Metabolic Epidemiology; in: Persons at High Risk of Cancer. An Approach to Cancer Etiology and Control; edited by J. F. Fraumeni, Academic Press, New York, NY, 1975, pp. 485–501.Search in Google Scholar

144. Brunnemann, K. D., S. S. Hecht, and D. Hoffmann: Analysis of N-Nitrosamines in Tobacco and Tobacco Smoke with the Aid of the Thermal Energy Analyzer; presented at the 30th TCRC, Nashville, TN, 1976, No. 38.Search in Google Scholar

145. Brunnemann, K. D. and D. Hoffmann: Analysis of Polynu-clear Aromatic Hydrocarbons in the Respiratory Environ-ment; in: Carcinogenesis - A Comprehensive Survey; edited by R. I. Freudenthal and P. W. Jones, Raven Press, New York, NY, 1976, pp. 283–297.Search in Google Scholar

146. Brunnemann, K. D., D. Hoffmann, E. L. Wynder, and G. B. Gori: Chemical Studies on Tobacco Smoke. XXXVII. Determination of tar, nicotine, and carbon monoxide in cigarette smoke. A comparison of international smoking conditions; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 441–449.Search in Google Scholar

147. Brunnemann, K. D., H. C. Lee, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XLVII. On the quantitative analysis of catechols and their reduction; Anal. Lett. 9 (1976) 939–955.Search in Google Scholar

148. Brunnemann, K. D., L. Yu, and D. Hoffmann: Gas Chro-matographic Determination of Hydrogen Cyanide and Cyanogen in Tobacco Smoke; presented at the 30th TCRC, Nashville, TN, 1976, No. 36.Search in Google Scholar

149. Hecht, S. S., C. B. Chen, and D. Hoffmann: Synthesis of N-nitrosamino aldehydes; Tetrahedron Lett. 8 (1976) 593–596.10.1016/S0040-4039(00)77919-6Search in Google Scholar

150. Hecht, S. S., M. Loy, and D. Hoffmann: On the Structure and Carcinogenicity of the Methylchrysenes; in: Carcinogenesis - A Comprehensive Survey; edited by R. I. Freudenthal and P. W. Jones, Raven Press, New York, NY, 1976, pp. 325–340.Search in Google Scholar

151. Hecht, S. S., R. M. Ornaf, M. Dong, and D. Hoffmann: Studies on Nonvolatile Nitrosamines in Tobacco; presented at the 30th TCRC, Nashville, TN, 1976, No. 27.Search in Google Scholar

152. Hecht, S. S., I. Schmeltz, D. Hoffmann, and E. L. Wynder: Chemical Studies on Tobacco Smoke. XL. Identification of carcinogens in tobacco; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder, et al., US Gov. Print. Off., Washington, DC, 1976, pp. 191–202.Search in Google Scholar

153. Hecht, S. S., T. C. Tso, and D. Hoffmann: Selective Reduction of Tumorigenicity of Tobacco Smoke. IV. Approaches to the reduction of nitrosamines and aromatic amines; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 535–545.Search in Google Scholar

154. Hoffmann, D., S. S. Hecht, K. D. Brunnemann, and E. L. Wynder: Analysis and formation of N-nitrosamines in tobacco and tobacco smoke; presented at the CORESTA Congress Tokyo, Japan, 1976, No. S017.Search in Google Scholar

155. Hoffmann, D., S. S. Hecht, R. M. Ornaf, E. L. Wynder, and T. C. Tso: Chemical Studies on Tobacco Smoke. XLII. Nitrosonornicotine: Presence in Tobacco, Formation and Carcinogenicity; in: Asbestos, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 14, 1976, pp. 307–320.Search in Google Scholar

156. Hoffmann, D., C. P. Patrianakos, K. D. Brunnemann, and G. B. Gori: Chemical Studies on Tobacco Smoke. XXXVI. Chromatographic determination of vinyl chloride in tobacco smoke; Anal. Chem. 48 (1976) 47–50.Search in Google Scholar

157. Hoffmann, D., I. Schmeltz, S. S. Hecht, and E. L. Wynder: Chemical Studies on Tobacco Smoke. XXXIX. On the identification of carcinogens, tumor promoters, and cocarcinogens in tobacco smoke; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 125–145.Search in Google Scholar

158. Hoffmann, D. and E. L. Wynder: Environmental Respiratory Carcinogenesis; in: Chemical Carcinogenesis; edited by C. E. Searle, Am. Chem. Soc. Monograph No. 173, Washington, DC, 1976, pp. 324–365.Search in Google Scholar

159. Hoffmann, D. and E. L. Wynder: Selective reduction of tumorigenicity of tobacco smoke. III. The reduction of polynuclear aromatic hydrocarbons in cigarette smoke; in: Smoking and Health. I: Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 495–504.Search in Google Scholar

160. Hoffmann, D. and E. L. Wynder: Smoking and occupational cancers; Prev. Med. 5 (1976) 245–261.Search in Google Scholar

161. Schmeltz, I., K. D. Brunnemann, D. Hoffmann, and A. Cornell: [Chemical Studies on Tobacco Smoke. XLV.] On the chemistry of cigar smoke: Comparisons Between Experimental Little and Large Cigars; Beitr. Tabakforsch. 8 (1976) 367–377.Search in Google Scholar

162. Schmeltz, I. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXXVIII. The physicochemical nature of cigarette smoke; in: Smoking and Health: I. Modifying the Risk for the Smoker; Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 13–34.Search in Google Scholar

163. Schmeltz, I. and D. Hoffmann: Formation of Polynuclear Aromatic Hydrocarbons from Combustion of Organic Matter; in: Carcinogenesis - Polynuclear Aromatic Hydro-carbons: Chemistry, Metabolism, and Carcinogenesis; edited by R. I. Freudenthal and P. W. Jones, Raven Press, New York, NY, 1976, pp. 225–239.Search in Google Scholar

164. Schmeltz, I., J. Tosk, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XLVI. Formation and determination of naphthalenes in cigarette smoke; Anal. Chem. 48 (1976) 645–650.Search in Google Scholar

165. Schmeltz, I., J. Tosk, G. Jacobs, and D. Hoffmann: The Redox Potential and Quinone Content of Cigarette Smoke; presented at the 30th TCRC, Nashville, TN, 1976, No. 44.Search in Google Scholar

166. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Use of Radioactive Tobacco Isolates for Studying the Formation of Selected Smoke Components; presented at the 30th TCRC, Nashville, TN, 1976, No. 35.Search in Google Scholar

167. Tso, T. C., G. B. Gori, and D. Hoffmann: Reduction of Nicotine and Tar in Tobacco and in Cigarettes Through Agricultural Techniques; in: Smoking and Health: I. Modi-fying the Risk for the Smoker; Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 35–48.Search in Google Scholar

168. Wynder, E. L. and D. Hoffmann: Tobacco and tobacco smoke; Semin. Oncol. 3 (1976) 5–15.Search in Google Scholar

169. Wynder, E. L., D. Hoffmann, and G. B. Gori (Editors): Smoking and Health: I. Modifying the Risk for the Smoker; Proc. 3rd World Conf. on Smoking and Health 1975, US Gov. Print. Off., Washington, DC, 1976.Search in Google Scholar

170. Brunnemann, K. D., J. D. Adams, and D. Hoffmann: Nonvol-atile N-Nitrosamines: Analysis in Tobacco and Tobacco Smoke by HPLC-TEA; presented at the 31st TCRC, Greens-boro, NC, 1977, No. 52.Search in Google Scholar

171. Brunnemann, K. D., G. Stahnke, and D. Hoffmann: Volatile Pyridines: Quantitative Analysis in Main- and Sidestream Smoke of Cigarettes and Cigars; presented at the 31st TCRC, Greensboro, NC, 1977, No. 36.Search in Google Scholar

172. Brunnemann, K. D., L. Yu, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XVII.] Assessment of carcino-genic volatile N-nitrosamines in tobacco and in mainstream and sidestream smoke from cigarettes; Cancer Res. 37 (1977) 3218–3222.Search in Google Scholar

173. Brunnemann, K. D., L. Yu, and D. Hoffmann: Chemical studies on tobacco smoke. XLIX. Gas chromatographic determination of hydrogen cyanide and cyanogen in tobacco smoke; J. Anal. Toxicol. 1 (1977) 38–42.Search in Google Scholar

174. Dong, M., D. Hoffmann, D. C. Locke, and E. Ferrand: Short Communication: The occurrence of caffeine in the air of New York City; Atmos. Environ. 11 (1977) 651–653.Search in Google Scholar

175. Dong, M. W., D. C. Locke, and D. Hoffmann: Characterization of aza-arenes in the basic organic portion of suspended particulate matter; Environ. Sci. Technol. 11 (1977) 612–618.Search in Google Scholar

176. Dong, M., D. C. Locke, and D. Hoffmann: Separation of aza-arenes by high pressure liquid chromatography; J. Chroma-togr. Sci. 15 (1977) 32–35.Search in Google Scholar

177. Dong, M., I. Schmeltz, R. Jacobs, and D. Hoffmann: Aza-arenes in Tobacco Smoke; presented at the 31st TCRC, Greensboro, NC, 1977, No. 43.Search in Google Scholar

178. Hecht, S. S., S. Carmella, and D. Hoffmann: Hydroxyphenyl Alcohols in Tobacco and Tobacco Smoke; presented at the 31st TCRC, Greensboro, NC, 1977, No. 51.Search in Google Scholar

179. Hecht, S. S., C. B. Chen, M. Dong, R. M. Ornaf, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LI. Studies on Non-volatile Nitrosamines in Tobacco. Beitr. Tabakforsch. 9 (1977) 1–6.Search in Google Scholar

180. Hecht, S. S., I. Schmeltz, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LVIII. Nitrogenous compounds in cigarette smoke and their possible precursors; presented at the 31st TCRC, Greensboro, NC, 1977, No. 3; in: Rec. Adv. Tobacco Sci. 3 (1977) 59–93.Search in Google Scholar

181. Hilfrich, J., S. S. Hecht, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XV. Effects of N’-nitrosonor-nicotine and N’-nitrosoanabasine in Syrian golden hamsters; Cancer Lett. 2 (1977) 169–176.Search in Google Scholar

182. Hoffmann, D., M. Dong, and S. S. Hecht: Chemical Studies on Tobacco Smoke. LII. Origin in tobacco smoke of N’-nitrosonornicotine, a tobacco-specific carcinogen: Brief Communication; J. Natl. Cancer Inst. 58 (1977) 1841–1844.Search in Google Scholar

183. Hoffmann, D., S. S. Hecht, I. Schmeltz, and E. L. Wynder: Polynuclear aromatic hydrocarbons: Occurrence, formation and carcinogenicity; in: Proc. Symp. Structural Correlates of Carcinogenesis and Mutagenesis: A Guide to Testing Priorities, FDA, Annapolis, MD, 1977, pp. 120–128.Search in Google Scholar

184. Hoffmann, D. and E. L. Wynder: The less harmful cigarette: present and future; World Smoking Health 2 (1977) 30–34.Search in Google Scholar

185. Hoffmann, D. and E. L. Wynder: Organic Particulate Pollutants. Chemical Analysis and Bioassays for Carcinoge-nicity; in: Air Pollution; edited by A. C. Stern, Academic Press, New York, NY, 1977, pp. 361–455.Search in Google Scholar

186. Patrianakos, C., K. D. Brunnemann, and D. Hoffmann: Aromatic Amines in Cigarette Smoke; presented at the 31st TCRC, Greensboro, NC, 1977, No. 44.Search in Google Scholar

187. Schmeltz, I., S. Abidi, and D. Hoffmann: [Chemical studies on tobacco smoke. XLVIII.] Tumorigenic agents in un-burned proc essed tobacco: N-nitrosodiethanolamine and 1,1-dimethylhydrazine; Cancer Lett. 2 (1977) 125–131.Search in Google Scholar

188. Schmeltz, I. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. L.] Nitrogen-containing compounds in tobacco and tobacco smoke. Chem. Rev. 77 (1977) 295–311.Search in Google Scholar

189. Schmeltz, I., D. Hoffmann, and B. Toth: Hydrazines: Occurence, analysis and carcinogenic activity as related to structure; in: Proc. Symp. Structural Correlates of Carcinogenesis and Mutagenesis: A Guide to Testing Priorities, FDA, Annapolis, MD, 1977, pp. 172–178.Search in Google Scholar

190. Schmeltz, I., J. Tosk, G. Jacobs, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XXXV.] The redox potential and quinone content of cigarette smoke; Anal. Chem. 49 (1977) 1924–1929.Search in Google Scholar

191. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Use of Radioactive Tracers to Determine Cigarette Smoke Components that Arise from Nicotine During Tobacco Combustion; presented at the 31st TCRC, Greensboro, NC, 1977, No. 17.Search in Google Scholar

192. Stellman, J. M. and D. Hoffmann: Occupational bladder cancer; Lancet 310 (1977) 563–564.Search in Google Scholar

193. Toth, B., L. Wallcave, K. Patil, I. Schmeltz, and D. Hoffmann: Induction of tumors in mice with the herbicide succinic acid 2,2-dimethylhydrazine; Cancer Res. 37 (1977) 3497–3500.Search in Google Scholar

194. Adams, J. D., K. D. Brunnemann, and D. Hoffmann: Determi-nation of Nitric Oxide in Unaged Smoke by GSC-TEA; presented at the 32nd TCRC, Montreal, Canada, 1978, No. 36.Search in Google Scholar

195. Brunnemann, K. D., J. D. Adams, D. P. S. Ho, and D. Hoffmann: The influence of tobacco smoke on indoor atmo-spheres. II. Volatile and tobacco specific nitrosamines in main- and sidestream smoke and their contribution to indoor pollution; in: Proc. 4th Joint Conf. on Sensing of Environ-mental Pollutants, Am. Chem. Soc., New Orleans, LA, 1978, pp. 876–880.Search in Google Scholar

196. Brunnemann, K. D. and D. Hoffmann: Chemical Studies on Tobacco Smoke. LIX. Analysis of volatile nitrosamines in tobacco smoke and polluted indoor environments; in: Environmental Aspec ts of N-Ni tr oso Compounds, IARC Sci. Publ. 19 (1978) 343–356.Search in Google Scholar

197. Brunnemann, K. D., G. Stahnke, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXI. Volatile pyridines: quantitative analysis in mainstream and sidestream smoke of cigarettes and cigars; Anal. Lett. A-11 (1978) 545–560.Search in Google Scholar

198. Carmella, S., S. S. Hecht, and D. Hoffmann: Subfractionation of the Weakly Acidic Fraction of Cigarette Smoke Conden-sate by Preparative High Pressure Liquid Chromatography; presented at the 32nd TCRC, Montreal, Canada, 1978, No. 42.Search in Google Scholar

199. Chen, C. B., S. S. Hecht, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XI.] Metabolic -hydroxylation of the tobacco-specific carcinogen, N’-nitrosonornicotine; Cancer Res. 38 (1978) 3639–3645.Search in Google Scholar

200. Chen, C. B., S. S. Hecht, E. LaVoie, and D. Hoffmann: Denitrosation of Tobacco Specific Nitrosamines by -Hydroxylation: An Approach to Their Reduction in Tobacco; presented at the 32nd TCRC, Montreal, Canada, 1978, No. 48.Search in Google Scholar

201. Chen, C. B., G. D. McCoy, S. S. Hecht, D. Hoffmann, and E. L. Wynder: [A Study of Chemical Carcinogenesis. X.] High pressure liquid chromatographic assay for -hydroxylation of N-nitrosopyrrolidine by isolated rat liver microsomes; Cancer Res. 38 (1978) 3812–3816.Search in Google Scholar

202. Dong, M., I. Schmeltz, and D. Hoffmann: Purification of quinolines for bioassay by preparative high pressure liquid chromatography; J. Chromatogr. 150 (1978) 269–272.Search in Google Scholar

203. Dong, M., I. Schmeltz, E. Jacobs, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LV.] Aza-arenes in tobacco smoke; J. Anal. Toxicol. 2 (1978) 21–25.Search in Google Scholar

204. Dong, M., I. Schmeltz, E. LaVoie, and D. Hoffmann: Aza-arenes in the respiratory environment: analysis and assays for mutagenicity; in: Carcinogenesis - Polynuclear Aromatic Hydrocarbons, Vol. 3; edited by R. W. Jones and R. I. Freudenthal, Raven Press, New York, NY, 1978, pp. 97-108.Search in Google Scholar

205. Hecht, S. S., S. Carmella, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LIV. Determination of hydroxybenzyl alcohols and hydroxyphenyl ethanols in tobacco and tobacco smoke; J. Anal. Toxicol. 2 (1978) 56-59.Search in Google Scholar

206. Hecht, S. S., C. B. Chen, N. Hirota, R. M. Ornaf, T. C. Tso, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XVI.] Tobacco-specific nitrosamines: Formation from nico-tine in vitro and during tobacco curing, and carcinogenicity in strain A mice; J. Natl. Cancer Inst. 60 (1978) 819-824.Search in Google Scholar

207. Hecht, S. S., C. B. Chen, and D. Hoffmann: [A Study of Chemical Carcinogenesis. VI.] Evidence for metabolic a-hydroxylation of N-nitrosopyrrolidine; Cancer Res. 38 (1978) 215-218.Search in Google Scholar

208. Hecht, S. S., C. B. Chen, EJ. LaVoie, and D. Hoffmann: Formation and metabolism of tobacco-specific N-nitros-amines in leaf; presented at the CORESTA Symposium Sofia, Bulgaria, 1978, No. S16.Search in Google Scholar

209. Hecht, S. S., C. B. Chen, R. M. Ornaf, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LVI. Tobacco-specific nitrosamines: origins, carcinogenicity and metabolism; in: Environmental Aspects of N-Nitroso Compounds, IARC Sci. Publ. 19 (1978) 395–413.Search in Google Scholar

210. Hecht, S. S., C. B. Chen, R. M. Ornaf, E. Jacobs, J. D. Adams, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LII. Reaction of nicotine and sodium nitrite: Formation of nitrosamines and fragmentation of the pyrrolidine ring; J. Org. Chem. 43 (1978) 72-76.Search in Google Scholar

211. Hecht, S. S., N. Hirota, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XII.] Comparative tumor initiating activity of 10-methylbenzo(a)pyrene, 7,10-dimethyl-benzo(a)pyrene, and benzo(a)pyrene; Cancer Lett. 5 (1978) 179-183.Search in Google Scholar

212. Hecht, S. S., N. Hirota, M. Loy, and D. Hoffmann: [A Study of Chemical Carcinogenesis. VIII.] Tumor initiating activity of fluorinated 5-methylchrysenes; Cancer Res. 38 (1978): 1694-1698.Search in Google Scholar

213. Hecht, S. S., E. LaVoie, R. Mazzarese, S. Amin, V. Bedenko, and D. Hoffmann: [A Study of Chemical Carcinogenesis. IX.] 1,2-Dihydro-1,2-dihydroxy-5-methylchrysene, a major activated metabolite of the environmental carcinogen, 5-methylchrysene; Cancer Res. 38 (1978) 2191-2194.Search in Google Scholar

214. Hecht, S. S., M. Loy, R. Mazzarese, and D. Hoffmann: A Study of Chemical Carcinogenesis. V. On the Carcinogenicity of 5-Methylchrysene: Structure-activity Studies and Metabolism; in: Polynuclear Aromatic Hydrocarbons and Cancer; edited by H. V. Gelboin and P. O. Ts'o, Academic Press, New York, NY, 1978, pp. 119-130.Search in Google Scholar

215. Hecht, S. S., M. Loy, R. Mazzarese, and D. Hoffmann: A Study of Chemical Carcinogenesis. VII. Synthesis and mutagenicity of modified chrysenes related to the carcinogen, 5-methylchrysene; J. Med. Chem. 21 (1978) 38–44.Search in Google Scholar

216. Hilfrich, J., I. Schmeltz, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XVII.] Effects of N-nitroso-diethanolamine and 1,1-diethanolhydrazine in Syrian golden hamsters; Cancer Lett. 4 (1978) 55-60.Search in Google Scholar

217. Hoffmann, D., K. D. Brunnemann, and J. Adams: Analysis of selected components in the smoke of little cigars; presented at the CORESTA Symposium Sofia, Bulgaria, 1978, No. S12.Search in Google Scholar

218. Hoffmann, D., I. Schmeltz, S. S. Hecht, K. D. Brunnemann, and E. L. Wynder: Volatile Carcinogens: Occurrence, Formation and Analysis; in: Prevention and Detection of Cancer, Part I: Prevention; edited by H. E. Nieburgs, Marcel Dekker, New York, NY, 1978, pp. 1943-1959.Search in Google Scholar

219. Hoffmann, D., I. Schmeltz, S. S. Hecht, and E. L. Wynder: Tobacco Carcinogenesis; in: Polycyclic Hydrocarbons and Cancer, Vol. 1: Chemistry; edited by H. V. Gelboin and P. O. Ts'o, Academic Press, New York, NY, 1978, pp. 85–117.Search in Google Scholar

220. Hoffmann, D. and E. L. Wynder: Identification and reduction of carcinogens in the respiratory environment; Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg. Orig. B, 166 (1978) 113–135.Search in Google Scholar

221. Schmeltz, I., K. D. Brunnemann, and D. Hoffmann: Analyti-cal Methods for Polynuclear Hydrocarbons, in: Prevention and Detection of Cancer, Part I: Prevention; edited by H. E. Nieburgs, Marcel Dekker, New York, NY, 1978, pp. 1973–1992.Search in Google Scholar

222. Schmeltz, I., K. G. Chiong, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LX.] Formation and determination of ethyl carbamate in tobacco and tobacco smoke; J. Anal. Toxicol. 2 (1978) 265–268.Search in Google Scholar

223. Schmeltz, I., J. Tosk, H. Hilfrich, N. Hirota, D. Hoffmann, and E. L Wynder: Bioassays of Naphthalene and Alkyl-naphthalene for Co-carcinogenic Activity. Relation to Tobacco Carcinogenesis; in: Carcinogenesis - A Compre-hensive Survey; edited by R. W. Jones and R. I. Freudenthal, Raven Press, New York, NY, 1978, pp. 47–60.Search in Google Scholar

224. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LIII. Use of radioactive tobacco isolates for studying the formation of smoke components; J. Agr. Food Chem. 26 (1978) 234–239.Search in Google Scholar

225. Weiss, L., M. Loy, S. S. Hecht, and D. Hoffmann: A Study of Chemical Carcinogenesis. IV. Synthesis of the carbon-14 labelled carcinogens 5-methylchrysene, 2-methylaniline, and 3-methyl-2-naphthylamine; J. Labelled Compd. Radio-pharm. 14 (1978) 119–131.Search in Google Scholar

226. Wynder, E. L., D. Hoffmann, G. D. McCoy, L. A. Cohen, and B. S. Reddy: Tumor Promotion and Cocarcinogenesis as Related to Man and His Environment; in: Carcinogenesis, Vol. 2: Mechanisms of Tumor Promotion and Cocarcinoge-nesis; edited by J. Slaga et al., Raven Press, New York, NY, 1978 pp. 59–77.Search in Google Scholar

227. Amin, S., S. S. Hecht, E. LaVoie, and D. Hoffmann: A Study of Chemical Carcinogenesis. XIX. Synthesis and mutageni-city of 5,11-dimethylchrysene and some methyl-oxidized derivatives of 5-methylchrysene; J. Med. Chem. 22 (1979) 1336–1340.Search in Google Scholar

228. Carmella, S., S. S. Hecht, and D. Hoffmann: Quantitative Analysis of Alkyl-2-hydroxy-2-cyclopentene-1-ones in Tobacco Smoke; presented at the 33rd TCRC, Lexington, KY, 1979, No. 54.Search in Google Scholar

229. DeVera, N., I. Schmeltz, S. S. Hecht, and D. Hoffmann: Moderately polar non-PAH neutral components in cigarette smoke; presented at the 33rd TCRC, Lexington, KY, 1979, No. 49.Search in Google Scholar

230. Hecht, S. S., S. Amin, A. Rivenson, and D. Hoffmann: A Study of Chemical Carcinogenesis. XX. Tumor initiating activity of 5,11-dimethylchrysene, 5,12-dimethylchrysene and 5-methylchrysene; Cancer Lett. 8 (1979) 65–70.Search in Google Scholar

231. Hecht, S. S., C. B. Chen, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XVII. Tobacco-specific nitros-amines: Occurrence, formation, carcinogenicity, and metabolism; Acc. Chem. Res. 12 (1979) 92–98.Search in Google Scholar

232. Hecht, S. S., C. B. Chen, G. D. McCoy, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XVIII. Tobacco-specific nitrosamines: Occurrence, carcinogenicity, and metabolism; in: Proceedings 8th Northeastern Regional Meeting, Am. Chem. Soc. Symp. Ser. 101 (1979) 125–152.Search in Google Scholar

233. Hecht, S. S., C. B. Chen, G. D. McCoy, D. Hoffmann, and L. A. Domellöf: [A Study of Chemical Carcinogenesis. XVIII.] -Hydroxylation of N-nitrosopyrrolidine and N’-nitrosonornicotine by human liver microsomes; Cancer Lett. 8 (1979) 35–41.Search in Google Scholar

234. Hecht, S. S., E. LaVoie, and D. Hoffmann: A Study of Chemical Carcinogenesis. XIII. Structure-activity relation-ships in polynuclear aromatic hydrocarbons; in: Proc. Lawrence Berkeley Lab. Conf. on Carbonaceous Particles in the Atmosphere; edited by T. Novakov, Natl. Techn. Inform. Serv., US Dept. Commerce, Springfield, VA, 1979, pp. 177-186.Search in Google Scholar

235. Hecht, S. S., E. LaVoie, R. Mazzarese, N. Hirota, T. Ohmori, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XVI.] Comparative mutagenicity, tumor-initiating activity, carcinogenicity, and in vitro metabolism of fluorinated 5-methylchrysenes; J. Natl. Cancer Inst. 63 (1979) 855-861.Search in Google Scholar

236. Hecht, S. S., R. Mazzarese, S. Amin, EJ. LaVoie, and D. Hoffmann: A Study of Chemical Carcinogenesis. XV. On the Metabolic Activation of 5-Methylchrysene; in: Polynu-clear Aromatic Hydrocarbons; edited by P. W. Jones and P. Leber, Ann Arbor Sci. Publ., Ann Arbor, MI, 1979, pp. 733-752.Search in Google Scholar

237. Hoffmann, D., J. D. Adams, K. D. Brunnemann, and S. S. Hecht: [Chemical Studies on Tobacco Smoke. LXII.] Assessment of tobacco-specific N-nitrosamines in tobacco products; Cancer Res. 39 (1979) 2505-2509.Search in Google Scholar

238. Hoffmann, D., J. D. Adams, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. LXV.] Formation and analysis of carbon monoxide in cigarette mainstream and sidestream smoke; Prev. Med. 8 (1979) 344-350.Search in Google Scholar

239. Hoffmann, D., K. D. Brunnemann, I. Schmeltz, and E. L. Wynder: Trace Analysis in Respiratory carcinogenesis; in: Trace Organic Analysis: A New Frontier in Analytical Chemistry; edited by H. S. Hertz and S. N. Chester, Natl. Bureau of Standards Special Publ. No. 519, US Govt. Print. Off, Washington, DC, 1979, pp. 131-141.Search in Google Scholar

240. Hoffmann, D., A. Rivenson, S. S. Hecht, J. Hilfrich, N. Kobayashi, and E. L. Wynder: Model studies in tobacco carcinogenesis with the Syrian golden hamster; Progr. Exp. Tumor Res. 24 (1979) 370-390.Search in Google Scholar

241. LaVoie, E., V. Bedenko, N. Hirota, S. S. Hecht, and D. Hoffmann: A Comparison of the Mutagenicity, Tumor-initiating Activity and Complete Carcinogenicity of Polynu-clear Aromatic Hydrocarbons; in: Polynuclear Aromatic Hydrocarbons; edited by P. W. Jones and P. Leber, Ann Arbor Sci. Publ., Ann Arbor, MI, 1979, pp. 705-721.Search in Google Scholar

242. LaVoie, E., L. Tulley, E. Fow, and D. Hoffmann: Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides, and disulfides; Mutat. Res. 67 (1979) 123-131.Search in Google Scholar

243. Patrianakos, C. and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXIV. On the analysis of aromatic amines in cigarette smoke; J. Anal. Toxicol. 3 (1979) 150-154.Search in Google Scholar

244. Piade, J. J, J. D. Adams, and D. Hoffmann: Alkaloids and Nonvolatile N-Nitrosamines in Tobacco and Smoke of French Cigarettes; presented at the 33rd TCRC, Lexington, KY, 1979, No. 56.Search in Google Scholar

245. Schmeltz, I., K. D. Brunnemann, and D. Hoffmann: Trace analysis in agricultural products: methods for hydrazines, carbamates, N-nitrosodiethanolamine and other compounds; in: Trace Organic Analysis: A New Frontier in Analytical Chemistry; edited by H. S. Hertz and S. N. Chester, Natl. Bureau of Standards Special Publ. No. 519, U. S. Govt. Print. Off, Washington, DC, 1979, pp. 297-309.Search in Google Scholar

246. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LXIII. On the fate of nicotine during py roly sis and in a burning cigarette; J. Agric. Food Chem. 27 (1979) 602-608.Search in Google Scholar

247. Tosk, J., I. Schmeltz, and D. Hoffmann: Hydrazines as mutagens in a histidine-requiring auxotroph of Salmonella typhimurium; Mutat. Res. 66 (1979) 247-252.Search in Google Scholar

248. Wynder, E. L. and D. Hoffmann: Rauchen und Gesundheit. Die Epidemiologie tabakbedingter Erkrankungen; Therapiewoche 29 (1979) 8747-8757.Search in Google Scholar

249. Wynder, E. L. and D. Hoffmann: Perforated filter-tip cigarettes: effect on tar, nicotine, and carbon monoxide intake; JAMA 241 (1979) 295.Search in Google Scholar

250. Wynder, E. L. and D. Hoffmann: Stopping smoking (Letter); New Engl. J. Med. 301 (1979) 390.Search in Google Scholar

251. Wynder, E. L. and D. Hoffmann: Smoking and Health: Pathogenic and Preventive Considerations; Bull. Schweiz. Akad. Med. Wiss. 35 (1979) 83–98.Search in Google Scholar

252. Wynder, E. L. and D. Hoffmann: Tobacco and Health. A societal challenge; New Engl. J. Med. 300 (1979) 894–903.Search in Google Scholar

253. Adams, J. D., J. J. Piade, and D. Hoffmann: The selective reduction of tobacco specific N-nitrosamines from cigarette smoke; presented at the 34th TCRC, Richmond, VA, 1980, No. 50.Search in Google Scholar

254. Brunnemann, K. D., D. Hoffmann, and T. C. Tso: The fate of diethanolamine in tobacco and cigarette smoke; presented at the 34th TCRC, Richmond, VA, 1980, No. 51.Search in Google Scholar

255. Carmella, S., S. S. Hecht, D. Hoffmann, and T. C. Tso: The formation of catechol in cigarette smoke; presented at the 34th TCRC, Richmond, VA, 1980, No. 30.Search in Google Scholar

256. Chen, C. B., S. S. Hecht, G. D. McCoy, and D. Hoffmann: Assays for metabolic -hydroxylation of N’-nitrosonornico-tine and N-nitrosopy rrolidine and the influence of modifying factors; in: N-Nitroso Compounds: Analysis, Formation and Occurrence, IARC Sci. Publ. 31 (1980) 349–359.Search in Google Scholar

257. Hecht, S. S., C. B. Chen, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XXIX.] Metabolic -hydroxylation and N-oxidation of N’-nitrosonornicotine; J. Med. Chem. 23 (1980) 1175–1178.Search in Google Scholar

258. Hecht, S. S., C. B. Chen, T. Ohmori, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XIX.] Comparative car-cinogenicity in F344 rats of the tobacco-specific nitros-amines, N’-nitrosonornicotine and 4-(N-methyl-N-nitros-amino)-1-(3-pyridyl)-1-butanone; Cancer Res. 40 (1980) 298–302.Search in Google Scholar

259. Hecht, S. S., C. B. Chen, R. Young, D. Lin, and D. Hoffmann: Metabolism of the tobacco-specific nitrosamines, N’-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone, in: N-Nitroso Compounds: Analysis, Formation and Occurrence, IARC Sci. Publ. 31 (1980) 755–765.Search in Google Scholar

260. Hecht, S. S., E. LaVoie, S. Amin, V. Bedenko, and D. Hoffmann: On the metabolic activation of the benzofluor-anthenes, in: Polynuclear Aromatic Hydrcarbons: Chemistry and Biological Effects; edited by A. Bjorseth and A. J. Dennis, Battelle Press, Columbus, OH, 1980, pp. 417–433.Search in Google Scholar

261. Hecht, S. S., A. Rivenson, and D. Hoffmann: Tumor-initiating activity of dihydrodiols formed metabolically from 5-methylchrysene; Cancer Res. 40 (1980) 1396–1399.Search in Google Scholar

262. Hoffmann, D., J. D. Adams, J. J. Piade, and S. S. Hecht: Chemical Studies on Tobacco Smoke. LXVIII. Analysis of volatile and tobacco-specific nitrosamines in tobacco products; in: N-Nitroso Compounds: Analysis, Formation and Occurrence, IARC Sci. Publ. 31 (1980) 507–516.Search in Google Scholar

263. Hoffmann, D., C. B. Chen, and S. S. Hecht: The role of volatile and nonvolatile N-nitrosamines in tobacco carcino-genesis; in: Banbury Report 3: A Safe Cigarette?; edited by G. B. Gori and F. B. Bock, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1980, pp. 113–127.Search in Google Scholar

264. Hoffmann, D., S. S. Hecht, and E. L. Wynder: The role of polynuclear aromatic hydrocarbons in tobacco carcinogene-sis; presented at the Polycyclic Aromatic Hydrocarbons Conf. of the Verein Deutscher Ingenieure, Hannover, Germany, 1979; VDI-Ber. 358 (1980) 335–350.Search in Google Scholar

265. Hoffmann, D. and I. Hoffmann: Oncology Overview on Organ Specific Carcinogenicity of Tobacco Products. 1. Epidemiology of Non-Respiratory Tract Cancer and Related Clinical Observations; Internatl. Cancer Res. Data Bank PB80-922907, US Dept. H. H. S., 1980.Search in Google Scholar

266. Hoffmann, D., T. C. Tso, and G. B. Gori: The Less Harmful Cigarette; Prev. Med. 9 (1980) 287–296.Search in Google Scholar

267. Hoffmann, D. and E. L. Wynder: The low yield cigarette. Editorial; Am. J. Public Health, 70 (1980) 1143–1144; Response to Letter to the Editor; Am. J. Public Health, 71 (1981) 536–537.Search in Google Scholar

268. LaVoie, E. J., S. S. Hecht, S. Amin, V. Bedenko, and D. Hoffmann: Identification of mutagenic dihydrodiols as metabolites of benzo(j)fluoranthene and benzo(k)fluoran-thene; Cancer Res. 40 (1980) 4528–4532.Search in Google Scholar

269. LaVoie, E. J., S. S. Hecht, D. Hoffmann, and E. L. Wynder: The less harmful cigarette and tobacco smoke flavors; Banbury Report 3: A Safe Cigarette?; edited by G. B. Gori and F. B. Bock, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1980, pp. 251–260.Search in Google Scholar

270. LaVoie, E., L. Tulley, V. Bedenko, and D. Hoffmann: Mutagenicity, tumor initiating activity and metabolism of tricyclic polynuclear aromatic hydrocarbons; in: Polynuclear Aromatic Hydrocarbons: Chemistry and Biological Effects.; edited by A. Bjorseth and A. J. Dennis, Battelle Press, Columbus, OH, 1980, pp. 1041–1057.Search in Google Scholar

271. Piade, J. J., J. D. Adams, and D. Hoffmann: The semi-volatile and gasphases of cigarette smoke from air cured tobacco: chromatographic profiling and effect of aging; presented at the 34th TCRC, Richmond, VA, 1980, No. 16.Search in Google Scholar

272. Piade, J. J. and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXVII. Quantitative determination of alkaloids in tobacco by liquid chromatography; J. Liq. Chromatogr. 3 (1980) 1505–1515.Search in Google Scholar

273. Rivenson, A., T. Ohmori, S. S. Hecht, and D. Hoffmann: Organotropic carcinogenicity of tobacco-specific N-nitros-amines, in: Biology of the Cancer Cell; edited by K. Letnan-sky, Kugler Publ., Amsterdam, The Netherlands, 1980, pp. 51–62.Search in Google Scholar

274. Rühl, C., J. D. Adams, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXVI. Comparative assessment of volatile and tobacco-specific N-nitrosamines in the smoke of selected cigarettes from the USA, West Germany and France; J. Anal. Toxicol. 4 (1980) 255–259.Search in Google Scholar

275. Schmeltz, I., K. D. Brunnemann, and D. Hoffmann: Aza-arenes and other nitrogen-containing compounds in the respiratory environment. Proc. Am. Inst. Chem. Engineers Symposium Ser. 196, 1980, pp. 312–320.Search in Google Scholar

276. Schmeltz, I., A. Wenger, and D. Hoffmann: TLC in the Analysis of the Respiratory Environment; in: Thin-layer Chromatography: Quantitative, Environmental, and Clinical Applications; edited by J. C. Touchstone and D. Rogers, J. Wiley and Sons, New York, NY, 1980, pp. 325–347.Search in Google Scholar

277. Adams, J. D., A. Castonguay, S. J. Lee, N. Vinchkoski, and D. Hoffmann: Formation and Transfer of 4-(Methylnitros-amino)-1-(3-pyridyl)-butanone (NNK) During Smoking; pres. at the 35th TCRC, Winston-Salem, NC, 1981, No. 49.Search in Google Scholar

278. Amin, S., V. Bedenko, E. LaVoie, S. S. Hecht, and D. Hoffmann: Study of chemical carcinogenesis. XXII. Syn-thesis of dihydrodiols as potential proximate carcinogens of benzofluoranthenes; J. Org. Chem. 46 (1981) 2573–2578.Search in Google Scholar

279. Amin, S., S. S. Hecht, and D. Hoffmann: Synthesis of angular ring methoxy-5-methylchrysenes and 5-methyl-chrysenols; J. Org. Chem. 46 (1981) 2394–2398.Search in Google Scholar

280. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXIX.] Assessment of the carcinogenic N-nitrosodiethanolamine in tobacco products and tobacco smoke; Carcinogenesis 2 (1981) 1123–1127.Search in Google Scholar

281. Brunnemann, K. D. and D. Hoffmann: Concurrent Gas Chromatographic Determination of Volatile, Nonvolatile, and Tobacco Specific N-Nitrosamines; presented at the 35th TCRC, Winston-Salem, NC, 1981, No. 33.Search in Google Scholar

282. Carmella, S., S. S. Hecht, and D. Hoffmann: Precursor Studies on Catechol in Cigarette Smoke; presented at the 35th TCRC, Winston-Salem, NC, 1981, No. 50.Search in Google Scholar

283. El-Bayoumy, K., E. J. LaVoie, S. S. Hecht, E. A. Fow, and D. Hoffmann: The influence of methyl substitution on the mutagenicity of nitronaphthalenes and nitrobiphenols; Mutat. Res. 81 (1981) 143–153.Search in Google Scholar

284. Hecht, S. S., S. Carmella, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXX.] Quantitative Analysis of Alkyl-2-hydroxy-2-cyclopenten-1-ones in Tobacco Smoke; J. Agric. Food Chem. 29 (1981) 401–404.Search in Google Scholar

285. Hecht, S. S., S. Carmella, H. Mori, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XX. Role of Catechol as a Major Cocarcinogen in the Weakly Acidic Fraction of Smoke Condensate; J. Natl. Cancer Inst. 66 (1981) 163–169.Search in Google Scholar

286. Hecht, S. S., C. B. Chen, R. Young, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXI.] Mass Spectra of Tobacco-specific Nitrosamines, Their Metabolites, and Related Compounds; Beitr. Tabakforsch. Int. 11 (1981) 57–66.Search in Google Scholar

287. Hecht, S. S., E. J. LaVoie, V. Bedenko, D. Hoffmann, D. J. Sardella, E. Boger, and R. Lehr: A Study of Chemical Carcinogenesis. XXXII. On the Metabolic Activation of Dibenzo[a, i]pyrene and Dibenzo[a, h]pyrene; in: Polynuclear Aromatic Hydrocarbons: Chemical Analysis and Biological Fate; edited by M. Cooke and A. J. Dennis, Battelle Press, Columbus, OH, 1981, pp. 43–54.Search in Google Scholar

288. Hecht, S. S., E. J. LaVoie, V. Bedenko, L. Pingaro, S. Katayama, D. Hoffmann, D. J. Sardella, E. Boger, and R. E. Lehr: Reduction of tumorigenicity and of dihydrodiol formation by fluorine substitution in the angular rings of dibenzo[a, i]pyrene; Cancer Res. 41 (1981) 4341–4345.Search in Google Scholar

289. Hoffmann, D. and J. D. Adams: [A Study of Tobacco Carcinogenesis. XXIII.] Carcinogenic tobacco-specific N-nitrosamines in snuff and in the saliva of snuff dippers; Cancer Res. 41 (1981) 4305–4308.Search in Google Scholar

290. Hoffmann, D., J. D. Adams, K. D. Brunnemann, and S. S. Hecht: Formation, occurrence and carcinogenicity of N-nitrosamines in tobacco products; in: N-Nitroso Compounds; edited by R. A. Scanlan and S. R. Tannenbaum, Am. Chem. Soc. Symp. Ser. 174, Washington, DC, 1981, pp. 247–273.10.1021/bk-1981-0174.ch018Search in Google Scholar

291. Hoffmann, D., A. Castonguay, A. Rivenson, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXII.] Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N’-nitrosonornicotine in Syrian golden hamsters; Cancer Res. 41 (1981) 2386–2393.Search in Google Scholar

292. Hoffmann, D. and I. Hoffmann: Oncology overview on organ specific carcinogenicity of tobacco products. 2. Bioassays, physicochemical analysis, and other experimental evidence; Internatl. Cancer Res. Data Bank PB81-922902, US Dept. H. H. S., 1981.Search in Google Scholar

293. LaVoie, E. J., A. Govil, G. Briggs, and D. Hoffmann: Mutagenicity of aminocarbazoles and nitrocarbazoles; Mutat. Res. 90 (1981) 337–344.10.1016/0165-1218(81)90056-2Search in Google Scholar

294. LaVoie, E. J., A. Rivenson, B. Bedenko, E. Kolb, T. Ohmori, and D. Hoffmann: Carcinogenicity in Syrian golden ham-sters of N-nitrosamines formed during nitrosation of spermi-dine; Cancer Detect. Prev. 4 (1981) 79–84.Search in Google Scholar

295. LaVoie, E. J., L. Tulley-Freiler, V. Bedenko, and D. Hoffmann: On the metabolic activation of methylated phenan-threnes; presented at the 72nd Ann. Meeting Am. Assoc. Cancer Res., 1981, No. 370.Search in Google Scholar

296. LaVoie, E. J., L. Tulley, V. Bedenko, and D. Hoffmann: Mutagenicity and methylated fluorenes and benzofluorenes; Mutat. Res. 91 (1981) 167–176.10.1016/0165-7992(81)90027-0Search in Google Scholar

297. LaVoie, E. J., L. Tulley-Freiler, V. Bedenko, Z. Girach, and D. Hoffmann: Comparative Studies on the Tumor-initiating Activity and Metabolism of Methylfluorenes and Methyl-benzofluorenes; in: Polynuclear Aromatic Hydrocarbons: Chemical Analysis and Biological Fate; edited by M. Cooke and A. J. Dennis, Battelle Press, Columbus, OH, 1981, pp. 417–427.Search in Google Scholar

298. LaVoie, E. J., L. Tulley-Freiler, V. Bedenko, and D. Hoff mann: Mutagenicity, tumor initiating activity and metabolism of methylphenanthrenes; Cancer Res. 41 (1981) 3441-3447.Search in Google Scholar

299. Melikian, A., EJ. LaVoie, D. Hoffmann, and E. L. Wynder: Volatile nitrosamines: analysis in breast fluid and blood of non-lactating women; Food Cosmet. Toxicol. 19 (1981) 757-759.Search in Google Scholar

300. Adams, J. D., K. D. Brunnemann, S. S. Hecht, and D. Hoffmann: Biogenesis and chemistry of alkaloid-derived N-nitrosamines; presented at the 184th Natl. Mtg., Am. Chem. Soc, 1982, No. 66.Search in Google Scholar

301. Adams, J. D., EJ. LaVoie, and D. Hoffmann: Analysis of methy lated polynuclear aromatic hy drocarbons by capillary gas chromatography. Influence of temperature on the pyro-synthesis of anthracene, phenanthrene, and their methy lated derivatives; J. Chromatogr. Sci. 20 (1982) 274-277.Search in Google Scholar

302. Adams, J. D., A. Shigematsu, P. Owens, EJ. LaVoie, and D. Hoffmann: Quinolines and methylquinolines in the main-stream smoke of commercial cigarettes; presented at the 36th TCRC, Raleigh, NC, 1982, No. 38.Search in Google Scholar

303. Brunnemann, K. D., S. S. Hecht, and D. Hoffmann: N-Nitrosamines: Environmental occurrence, in vivo formation and metabolism; J. Toxicol. Clin. Toxicol. 19 (1982) 661-688.Search in Google Scholar

304. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXIV.] Pyrolytic origins of major gas phase constituents of cigarette smoke; presented at the 36th TCRC, Raleigh, NC, 1982, No. 3; in: Rec. Adv. Tobacco Sci. 8 (1982) 103-140.Search in Google Scholar

305. Brunnemann, K. D., J. C. Scott, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXII.] N-Nitrosomorpholine and other volatile N-nitrosamines in snuff tobacco; Carcinogenesis 3 (1982) 693-696.Search in Google Scholar

306. Carmella, S., S. S. Hecht, D. Hoffmann, and T. C. Tso: Cellulose and modified cellulose as precursors to catechol in cigarette smoke; presented at the 36th TCRC, Raleigh, NC, 1982, No. 39.Search in Google Scholar

307. Castonguay, A., S. S. Hecht, D. Hoffmann, G. D. Stoner, and H. AJ. Schut: Metabolism of tobacco-specific nitrosamines in cultured human tissues; presented at the 73rd Ann. Meeting Am. Assoc. Cancer Res., 1982, No. 333.Search in Google Scholar

308. El-Bayoumy, K., S. S. Hecht, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XLVI.] Comparative tumor initiating activity on mouse skin of 6-nitrobenzo[a]pyrene, 6-nitrochrysene, 3-nitropyrene, 1-nitropyrene and their parent hy drocarbons; Cancer Lett. 16 (1982) 333-337.Search in Google Scholar

309. Gutenmann, W. H., CA. Bache, DJ. Lisk, D. Hoffmann, J. D. Adams, and D. C. Elfving: Cadmium and nickel in smoke of cigarettes prepared from tobacco cultured on municipal sludge-amended soil; J. Toxicol. Environ. Health 10 (1982) 423–431.Search in Google Scholar

310. Hecht, S. S., A. Castonguay, F. -L. Chung, D. Hoffmann, and G. D. Stoner: Recent studies on the metabolic activation of cyclic nitrosamines; in: Banbury Report 12: Nitrosamines and Human Cancer; edited by P. N. Magee, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1982, pp. 103-120.Search in Google Scholar

311. Hecht, S. S., G. D. McCoy, B. C. Chen, and D. Hoffmann: The metabolism of cyclic nitrosamines; in: N-Nitroso Compounds; edited by RA. Scanlan and S. R. Tannenbaum, Am. Chem. Soc. Symp. Ser. 174, Washington, DC, 1982, pp. 49-75.10.1021/bk-1981-0174.ch004Search in Google Scholar

312. Hecht, S. S., R. Young, A. Rivenson, and D. Hoffmann: On the metabolic activation of N-nitrosomorpholine and N’-nitrosonornicotine: effects of deuterium substitution; in: N-Nitroso Compounds: Occurrence and Biological Effects, IARC Sci. Publ. 41 (1982) 499-507.Search in Google Scholar

313. Hoffmann, D., J. D. Adams, A. Rivenson, and S. S. Hecht: Alkaloid-derived N-nitrosamines, a major group of tobacco carcinogens; presented at the 13th International Cancer Congress, Seattle, 1982, No. 2292.Search in Google Scholar

314. Hoffmann, D., J. D. Adams, K. D. Brunnemann, A. Rivenson, and S. S. Hecht: Tobacco-specific N-Nitrosamines: Occur-rence and Bioassays; in: N-Nitroso Compounds: Occurrence and Biological Effects, IARC Sci. Publ. 41 (1982) 309–318.Search in Google Scholar

315. Hoffmann, D., J. D. Adams, N. Vinchkoski, and T. C. Tso: On the fate of nicotine-14C during leaf curing and smoking; presented at the CORESTA Symposium Winston-Salem, NC, 1982, No. S04.Search in Google Scholar

316. Hoffmann, D., K. D. Brunnemann, J. D. Adams, A. Rivenson, and S. S. Hecht: N-Nitrosamines in tobacco carcinogenesis; in: Banbury Report 12: Nitrosamines and Human Cancer; edited by P. N. Magee, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1982, pp. 211–225.Search in Google Scholar

317. Hoffmann, D., K. D. Brunnemann, A. Rivenson, and S. S. Hecht: N-Nitrosodiethanolamine: Analysis, formation in tobacco products and carcinogenicity in Syrian golden hamsters; presented at the 7th International Meeting on N-Nitroso Compounds, Tokyo, Japan, 1981; in: N-Nitroso Compounds: Occurrence and Biological Effects, IARC Sci. Publ. 41 (1982) 299–307.Search in Google Scholar

318. Hoffmann, D. and I. Hoffmann: Experimental Carcinogene-sis with Tobacco Products; in: Health Consequences of Smoking - Cancer. A Report of the Surgeon General, Part III, US Department of Health and Human Services, Washington, DC, DHHS (PHS) 82–50179, 1982, pp. 181–235.Search in Google Scholar

319. Hoffmann, D., E. J. LaVoie, and S. S. Hecht: Polynuclear aromatic hydrocarbons: effect of chemical structure on tumorigenicity; in: Polynuclear Aromatic Hydrocarbons: Physical and Biological Chemistry; edited by M. Cooke et al., Battelle Press, Columbus, OH, 1982, pp. 1–19.Search in Google Scholar

320. Hoffmann, D. and E. L. Wynder: Radioactivity in cigarette smoke; New Engl. J. Med. 307 (1982) 312.Search in Google Scholar

321. Hoffmann, D. and E. L. Wynder: Tobacco and tobacco smoke. A continuing public health issue; Tobacco J. Int. 1 (1982) 83–85.Search in Google Scholar

322. LaVoie, E. J., S. Amin, S. S. Hecht, K. Furuya, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XXXVIII.] Tumor-initiating activity of dihydrodiols of benzo(b)fluoranthene, benzo(j)fluoranthene, and benzo(k)-fluoranthene; Carcinogenesis 3 (1982) 49–52.Search in Google Scholar

323. LaVoie, E. J., V. Bedenko, L. Tulley-Freiler, and D. Hoffmann: Tumor-initiating activity and metabolism of poly-methylated phenanthrenes; Cancer Res. 42 (1982) 4045–4049.Search in Google Scholar

324. LaVoie, E. J., G. Briggs, V. Bedenko, and D. Hoffmann: Mutagenicity of substituted carbazoles in Salmonella typhimurium; Mutat. Res. 101 (1982) 141–150.Search in Google Scholar

325. LaVoie, E. J., S. S. Hecht, V. Bedenko, and D. Hoffmann: Identification of the mutagenic metabolites of fluoranthene, 2-methylfluoranthene, and 3-methylfluoranthene. Carcino-genesis 3 (1982) 841–846.Search in Google Scholar

326. LaVoie, E. J, A. Shigematsu, and D. Hoffmann: Aromatic amines and N-heterocyclics in tobacco distillates; presented at the 184th Natl. Mtg. Am. Chem. Soc., 1982, No. 53.Search in Google Scholar

327. Lee, S. J., J. D. Adams, and D. Hoffmann: On the occurrence and analysis of nitrocatechol(s) in cigarette smoke; pre-sented at the 36th TCRC, 1982, Raleigh, NC, No. 12.Search in Google Scholar

328. Melikian, A. A., E. J. LaVoie, S. S. Hecht, and D. Hoffmann: Influence of a bay region methyl group on formation of 5-methylchrysene dihydrodiol epoxide: DNA adducts in mouse skin; Cancer Res. 42 (1982) 1239–1242.Search in Google Scholar

329. Scott, J. C., K. D. Brunnemann, and D. Hoffmann: N-Nitroso-proline, an indicator for N-nitrosation of amines in tobacco products; presented at the 36th TCRC, 1982, Raleigh, NC, No. 40.Search in Google Scholar

330. Tso, T. C., J. F. Chaplin, J. D. Adams, and D. Hoffmann: Simple Correlation and Multiple Regression among Leaf and Smoke Characteristics of Burley Tobaccos; Beitr. Tabakforsch. Int. 11 (1982) 141–150.Search in Google Scholar

331. Wynder, E. L. and D. Hoffmann: Tobacco; in: Cancer Epidemiology and Prevention; edited by D. Schottenfeld and J. J. F. Fraumeni, Saunders, Philadelphia, PA, 1982, pp. 277–292 (Chapter 15).Search in Google Scholar

332. Adams, J. D., K. D. Brunnemann, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXV.] Rapid method for the analysis of tobacco-specific N-nitrosamines by GLC-TEA. J. Chromatogr. 256 (1983) 347–351.Search in Google Scholar

333. Adams, E. A., E. J. LaVoie, and D. Hoffmann: Mutagenicity and metabolism of azaphenanthrenes; in: Polynuclear Aromatic Hydrocarbons - Formation, Metabolism and Measurements; edited by M. Cooke and A. J. Dennis, Battelle Press, Columbus, OH, 1983, pp. 73–87.Search in Google Scholar

334. Adams, J. D., E. J. LaVoie, A. Shigematsu, P. Owens, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXX.] Quinoline and methylquinolines in cigarette smoke: Com-parative data and the effect of filtration; J. Anal. Toxicol. 7 (1983) 293–296.Search in Google Scholar

335. Adams, J. D., S. J. Lee, N. Vinchkoski, A. Castonguay, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXIII.] On the formation of the tobacco-specific carcino-gen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone during smoking; Cancer Lett. 17 (1983) 339–346.Search in Google Scholar

336. Brunnemann, K. D. and D. Hoffmann: GC-TEA of NDELA from tobacco products; in: Environmental Carcinogens -Selected Methods of Analysis. Vol. 6: N-Nitroso Com-pounds, IARC Sci. Publ. 45 (1983) 399–402.Search in Google Scholar

337. Brunnemann, K. D. and D. Hoffmann: N-Nitrosodiethanol-amine in tobacco and mainstream and sidestream smoke; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 85–92.Search in Google Scholar

338. Brunnemann, K. D., J. Masaryk, and D. Hoffmann: The role of tobacco stems in the formation of N-nitrosamines in tobacco and cigarette mainstream and sidestream smoke; presented at the 37th TCRC, Washington, DC, 1983, No. 6.10.1021/jf00120a020Search in Google Scholar

339. Brunnemann, K. D., J. Masaryk, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXI.] Role of tobacco stems in the formation of N-nitrosamines in tobacco and cigarette mainstream and sidestream smoke; J. Agric. Food Chem. 31 (1983) 1221–1224.Search in Google Scholar

340. Brunnemann, K. D., J. C. Scott, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXIX.] N-Nitrosoproline, an indicator for N-nitrosation of amines in processed tobacco; J. Agric. Food Chem. 31 (1983) 905–909.Search in Google Scholar

341. Carmella, S. C., S. S. Hecht, D. Hoffmann, J. J. Lam, and T. C. Tso: Effects of carboxymethylation of tobacco fiber on smoke catechol levels; presented at the 37th TCRC, Washington, DC, 1983, No. 40.Search in Google Scholar

342. Eisenbrand, G., M. Archer, K. D. Brunnemann, D. Fine, S. S. Hecht, D. Hoffmann, J. Krull, and K. S. Webb: Problems of contamination and artifact formation in nitrosamine sam-pling and analysis; in: Environmental Carcinogens - Se-lected Methods of Analysis, Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 25–34.Search in Google Scholar

343. Gutenmann, W. H., D. J. Lisk, D. Hoffmann, and J. D. Adams: Selenium in particulates and gaseous fractions of smoke from cigarettes prepared from tobacco grown on fly-ash-amended soil; J. Toxicol. Environ. Health 12 (1983) 385–393.Search in Google Scholar

344. Hecht, S. S., J. D. Adams, and D. Hoffmann: HPLC-TEA of Tobacco-Specific Nitrosamines, in: Environmental Carcino-gens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. No., 45 (1983) 429–436.Search in Google Scholar

345. Hecht, S. S., J. D. Adams, and D. Hoffmann: Tobacco-specific Nitrosamines in Tobacco and Tobacco Smoke; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6. N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 93-101.Search in Google Scholar

346. Hecht, S. S., J. D. Adams, S. Numoto, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XXV. Induction of respiratory tract tumors in Syrian golden hamsters by a single dose of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and the effect of smoke inhalation; Carcinogenesis 4 (1983) 1287-1290.Search in Google Scholar

347. Hecht, S. S., A. Castonguay, and D. Hoffmann: Nasal cavity carcinogens: possible routes of metabolic activation; in: Nasal Tumors in Animals and Man, Vol. 3: Experimental Nasal Carcinogenesis; edited by G. Reznik and S. F. Stinson, CRC Press Inc., Boca Raton, FL, 1983, pp. 201-232.Search in Google Scholar

348. Hecht, S. S., A. Castonguay, A. Rivenson, B. Mu, and D. Hoffmann: Tobacco-specific nitrosamines: carcinogenicity, metabolism, and possible role in human cancer; J. Environ. Sci. Health C1 1 (1983) 1-54.Search in Google Scholar

349. Hoffmann, D., J. D. Adams, and N. J. Haley: [Chemical Studies on Tobacco Smoke. LXXVI.] Reported cigarette smoke values: a closer look; Amer. J. Public Health 73 (1983) 1050-1053.Search in Google Scholar

350. Hoffmann, D. and K. D. Brunnemann: GC-TEA of Volatile Nitrosamines from Tobacco Products; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 363-366.Search in Google Scholar

351. Hoffmann, D. and K. D. Brunnemann: [A Study of Tobacco Carcinogenesis.] XXVI. Endogenous formation of N-nitrosoproline in cigarette smokers; Cancer Res. 43 (1983) 5570-5574.Search in Google Scholar

352. Hoffmann, D., K. D. Brunnemann, and K. S. Webb: Volatile nitrosamines in tobacco and mainstream and sidestream smoke and indoor environments; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 69-83.Search in Google Scholar

353. Hoffmann, D., N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Cigarette sidestream smoke: Formation, analysis, and model studies on the uptake by nonsmokers; US-Japan Meeting., New Etiology of Lung Cancer, Honolulu, Hawaii, 1983.Search in Google Scholar

354. Hoffmann, D., N. J. Haley, K. D. Brunnemann, and E. L. Wynder: On the endogenous formation of N-nitrosamines in cigarette smokers; presented at the 74th Ann. Meeting Am. Assoc. Cancer Res., 1983, No. 241.Search in Google Scholar

355. Hoffmann, D., N. J. Haley, K. D. Brunnemann, and E. L. Wynder: On the endogenous formation of N-nitrosamines in cigarette smokers; Proc. Am. Assoc. Cancer Res. 24 (1983) 61-63.Search in Google Scholar

356. Hoffmann, D. and S. S. Hecht: Tobacco and Tobacco Smoke (Volatile and Tobacco-Specific Nitrosamines). II. 2. a: General Aspects; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 63-67.Search in Google Scholar

357. Hoffmann, D., S. S. Hecht, N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Tobacco Carcinogenesis: Metabolic Studies in Humans; in: Human Carcinogenesis; edited by CC. Harris and H. N. Autrup, Academic Press, New York, NY, 1983, pp. 809-832.Search in Google Scholar

358. Hoffmann, D., S. S. Hecht, and E. L. Wynder: Tumor promot-ers and cocarcinogens in tobacco carcinogenesis; Environ. Health Perspect. 50 (1983) 247-257.Search in Google Scholar

359. Hoffmann, D., A. Rivenson, J. D. Adams, A. Juchatz, N. Vinchkoski, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXIV.] Effects of route of administration and dose on the carcinogenicity of N-nitrosodiethanolamine in the Syrian golden hamster; Cancer Res. 43 (1983) 2521-2524.Search in Google Scholar

360. Hoffmann, D., E. L. Wynder, A. Rivenson, EJ. LaVoie, and S. S. Hecht: Skin Bioassays in Tobacco Carcinogenesis; in: Progress in Experimental Tumor Research. Vol. 26: Skin Painting Techniques and in vivo Carcinogenesis Bioassays; edited by F. Homburger, Karger, Basel, Switzerland, 1983, pp. 43-67.Search in Google Scholar

361. LaVoie, EJ., E. A. Adams, and D. Hoffmann: Identification of the metabolites of benzo(f)quinoline and benzo(h)-quinoline formed by rat liver homogenate; Carcinogenesis 4 (1983) 1133-1138.Search in Google Scholar

362. LaVoie, EJ., E. A. Adams, A. Shigematsu, and D. Hoffmann: On the metabolism of quinoline and isoquinoline: possible molecular basis for differences in biological activities; Carcinogenesis 4 (1983) 1169-1173.Search in Google Scholar

363. LaVoie, EJ., D. T. Coleman, R. L. Tonne, and D. Hoffmann: Mutagenicity, Tumor Initiating Activity and Metabolism of Methylated Anthracenes, in: Polynuclear Aromatic Hydro-carbons - Formation, Metabolism and Measurements; edited by M. Cooke and A J. Dennis, Battelle Press, Columbus, OH, 1983, pp. 785-798.Search in Google Scholar

364. LaVoie, EJ., S. S. Hecht, and D. Hoffmann: Molecular basis for the structure-carcinogenicity relationships of polynuclear aromatic hydrocarbons; in: Structure-Activity Correlation as a Predictive Tool in Toxicology. Fundamentals, Methods, and Application; edited by L. Goldberg, Hemisphere Publ. Co., New York, NY, 1983, pp. 263-274.Search in Google Scholar

365. LaVoie, EJ., L. Tulley-Freiler, V. Bedenko, and D. Hoffmann: Mutagenicity of substituted phenanthrenes in Salmonella typhimurium; Mutat. Res. 116 (1983) 91-102.Search in Google Scholar

366. Masaryk, J., K. D. Brunnemann, D. Hoffmann: Model studies on nicotine analogues, synthesis and nitrosation reactions; presented at the 37th TCRC, Washington, DC, 1983, No. 8.Search in Google Scholar

367. Melikian, AA., EJ. LaVoie, S. S. Hecht, and D. Hoffmann: 5-Methylchrysene metabolism in mouse epidermis in vivo, diol epoxide-DNA adduct persistence, and diol epoxide reactivity with DNA as potential factors influencing the predominance of 5-methylchrysene-1,2-diol-3,4-epoxide-DNA adducts in mouse epidermis; Carcinogenesis 4 (1983) 843-849.Search in Google Scholar

368. Melikian, A. A., EJ. LaVoie, S. S. Hecht, and D. Hoffmann: On the enhancing effect of a bay-region methyl group in 5-methylchrysene carcinogenesis; in: Polynuclear Aromatic Hydrocarbons Formation, Metabolism and Measurements; edited by M. Cooke and AJ. Dennis, Battelle Press, Columbus, OH, 1983, pp. 861-875.Search in Google Scholar

369. Rice, J. E., V. Bedenko, EJ. LaVoie, and D. Hoffmann: Studies on the metabolism of fluoranthene, 2-methy lfluoran-thene, and 3-methylfluoranthene; in: Polynuclear Aromatic Hydrocarbons - Formation, Metabolism and Measurements; edited by M. Cooke and AJ. Dennis, Battelle Press, Columbus, OH, 1983, pp. 1009-1020.Search in Google Scholar

370. Rice, J. E., EJ. LaVoie, and D. Hoffmann: Synthesis of the isomeric phenols and trans-2,3-dihydrodiol of fluoranthene; J. Org. Chem. 48 (1983) 2360-2363.Search in Google Scholar

371. Rivenson, A., K. Furuya, S. S. Hecht, and D. Hoffmann: Experimental nasal cavity tumors induced by tobacco-specific nitrosamines (TSNA); in: Nasal Tumor in Animals and Man, Vol. 3: edited by G. Reznik and S. F. Stinson, CRC Press Inc., Boca Raton, FL, 1983, pp. 79-113.Search in Google Scholar

372. Shigematsu, A., J. D. Adams, J. Camanzo, EJ. LaVoie, and D. Hoffmann: Steam-volatile components in the tobacco and mainstream smoke of cigarettes with low ‘tar’ yields; presented at the 37th TCRC, Washington, DC, 1983, No. 12.Search in Google Scholar

373. Tso, T. C., J. D. Adams, NJ. Haley, and D. Hoffmann: The smokers’ dependence on nicotine and the fate of nicotine during tobacco curing and smoking, and its reduction; in: Proc. 5th World Conf. on Smoking and Health, Winnipeg, Canada, 1983, pp. 229-238.Search in Google Scholar

374. Wenke, G. and D. Hoffmann: A study of betel quid carcinogenesis. 1. On the in vitro N-nitrosation of arecoline; Carcinogenesis 4 (1983) 169-172.Search in Google Scholar

375. Adams, J. D., EJ. LaVoie, M. O'Donnell, and D. Hoffmann: On the pharmacokinetics of tobacco-specific N-nitros-amines; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 779–785.Search in Google Scholar

376. Adams, J. D., S. J. Lee, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXVIII.] Carcinogenic agents in cigarette smoke and the influence of nitrate on their formation; Carcinogenesis 5 (1984) 221–223.Search in Google Scholar

377. Adams, J. D., P. Owens-Tucciarone, and D. Hoffmann: Tobacco carcinogenesis and asbestos fibers: a model study; presented at the 75th Ann. Meeting Am. Assoc. Cancer Res., Toronto, Canada, 1984.Search in Google Scholar

378. Brunnemann, K. D., S. J. Lee, S. Adams, and D. Hoffmann: Occurrence of N-nitrosamines in chewing tobacco: a closer look; presented at the 38th TCRC, Atlanta, GA, 1984, No. 26.Search in Google Scholar

379. Brunnemann, K. D., J. C. Scott, N. J. Haley, and D. Hoffmann: Endogenous formation of N-nitrosoproline upon cigarette smoke inhalation; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 819–828.Search in Google Scholar

380. Brunnemann, K. D., J. C. Scott, and D. Hoffmann: Develop-ment of an HPLC postcolumn photolysis detector for the determination of N-nitrosamides; presented at the CO-RESTA Congress Vienna, Austria, 1984, No. S11.Search in Google Scholar

381. Carmella, S. G., S. S. Hecht, T. C. Tso, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXVII.] Roles of tobacco cellulose, sugars, and chlorogenic acid as precursors to catechol in cigarette smoke; J. Agric. Food Chem. 32 (1984) 267–273.Search in Google Scholar

382. El-Bayoumi, K., M. O'Donnell, S. S. Hecht, and D. Hoffmann: The influence of tobacco nitrate on aromatic amines and nitro-aromatics in cigarette smoke; presented at the 38th TCRC, 1984, Atlanta, GA, No. 36.Search in Google Scholar

383. Hecht, S. S., A. Castonguay, F. -L. Chung, and D. Hoffmann: Carcinogenicity and metabolism activation of tobacco-specific nitrosamines: current status and future prospects; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 763–778.Search in Google Scholar

384. Hoffmann, D., K. D. Brunnemann, and J. D. Adams: Tobacco-specific N-nitrosamines (TSNA): recent progress on occurrence, formation and reduction; presented at the CORESTA Congress Vienna, Austria, 1984, No. S15.Search in Google Scholar

385. Hoffmann, D., K. D. Brunnemann, J. D. Adams, and N. J. Haley: Indoor air pollution by tobacco smoke: model studies on the uptake by nonsmokers; in: Indoor Air. Radon, Passive Smoking, Particulates and Housing Epidemiology. Proc. 3rd Internatl. Conf. on Indoor Air Quality and Climate Stock-holm, Sweden, Vol. 2, D 17, 1984, pp. 313–318.Search in Google Scholar

386. Hoffmann, D., K. D. Brunnemann, J. D. Adams, and S. S. Hecht: Formation and analysis of N-nitrosamines in tobacco products and their endogenous formation in tobacco con-sumers; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 743–762.Search in Google Scholar

387. Hoffmann, D., N. J. Haley, J. D. Adams, and K. D. Brunne-mann: Tobacco Sidestream Smoke: Uptake by Nonsmokers; Prev. Med. 13 (1984) 608–617.Search in Google Scholar

388. Hoffmann, D., A. Rivenson, S. Amin, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXVII.] Dose-Response Study on the Carcinogenicity of Tobacco-Specific N-Nitrosamines in F344 rats; J. Cancer Res. Clin. Oncol. 108 (1984) 81–86.Search in Google Scholar

389. LaVoie, E. J., A. Shigematsu, E. A. Adams, J. Rigotty, and D. Hoffmann: Tumor-initiating activity of quinoline and methylated quinolines on the skin of SENCAR mice; Cancer Lett. 22 (1984) 269–273.Search in Google Scholar

390. Melikian, A. A., S. Amin, S. S. Hecht, D. Hoffmann, J. Pataki, and R. G. Harvey: Identification of the major adducts formed by reaction of 5-methylchrysene anti-dihydrodiol epoxides with DNA in vitro; Cancer Res. 44 (1984) 2524-2529.Search in Google Scholar

391. Sasson, I. M., D. T. Coleman, EJ. LaVoie, D. Hoffmann, and E. L. Wynder: Influence of diet and smoking on the mutage-nic activity of human urine: vegan diet increases mutageni-city; presented at the 75th Ann. Meeting Am. Assoc. Cancer Res., Toronto, Canada, 1984, No. 102.Search in Google Scholar

392. Wenke, G., K. D. Brunnemann, D. Hoffmann, and S. V. Bhide: A Study of Betel Quid Carcinogenesis. 4. Analysis of the saliva of betel chewers. A preliminary report; J. Cancer Res. Clin. Oncol. 108 (1984) 110-113.Search in Google Scholar

393. Wenke, G., A. Rivenson, K. D. Brunnemann, and D. Hoffmann: A Study of Betel Quid Carcinogenesis. 2. On the formation of N-nitrosamines during betel quid chewing; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 859-866.Search in Google Scholar

394. Wenke, G., A. Rivenson, and D. Hoffmann: A Study of Betel Quid Carcinogenesis. 3. 3-(Methylnitrosamino)-propionitrile, a powerful carcinogen in F344 rats; Carcinogenesis 5 (1984) 1137-1140.Search in Google Scholar

395. Wynder, E. L., M. T. Goodman, and D. Hoffmann: Demo-graphic aspects of the low-yield cigarette; J. Natl. Cancer Inst. 72 (1984) 817-822.Search in Google Scholar

396. Adams, J. D., EJ. LaVoie, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXVIII.] On the pharmacokinetics of tobacco-specific N-nitrosamines in Fischer rats; Carcinogenesis 6 (1985) 509-511.Search in Google Scholar

397. Adams, J. D., EJ. LaVoie, KJ. O'Mara-Adams, D. Hoffmann, K. D. Carey, and M. V. Marshall: [A Study of Tobacco Carcinogenesis. XXIX.] Pharmacokinetics of N’-nitrosonor-nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-buta-none in laboratory animals; Cancer Lett. 28 (1985) 195-201.Search in Google Scholar

398. Adams, J. D., KJ. O'Mara-Adams, and D. Hoffmann: On the mainstream-sidestream distribution of smoke components from commercial cigarettes; presented at the 39th TCRC, Montreal, Canada, 1985, No. 34.Search in Google Scholar

399. Bache, CA., DJ. Lisk, GJ. Doss, D. Hoffmann, and J. D. Adams: Cadmium and nickel in mainstream particulates of cigarettes containing tobacco grown on a low cadmium soil-sludge mixture; J. Environ. Toxicol. 16 (1985) 547-552.Search in Google Scholar

400. Brunnemann, K. D., L. Genoble, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXIV.] N-Nitrosamines in chewing tobacco: an international comparison; J. Agr. Food Chem. 33 (1985) 1178-1181.Search in Google Scholar

401. Chou, D., K. D. Brunneman, J. D. Adams, and D. Hoffmann: On the isolation and identification of new tobacco-specific N-nitrosamines; presented at the 39th TCRC, Montreal, Canada, 1985, No. 22.Search in Google Scholar

402. El-Bayoumy, K., M. O'Donnell, S. S. Hecht, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXII.] On the analysis of 1-nitronaphthalene, 1-nitropyrene, and 6-nitrochrysene in cigarette smoke; Carcinogenesis 6 (1985) 505-507.Search in Google Scholar

403. Haley, NJ. and D. Hoffmann: Analysis for nicotine and cotinine in hair to determine cigarette smoker status; Clin. Chem. 31 (1985) 1598-1600.Search in Google Scholar

404. Haley, NJ., D. W. Sepkovic, D. Hoffmann, and E. L. Wynder: Cigarette smoking as a risk for cardiovascular disease. Part VI. Compensation with nicotine availability as a single variable; Clin. Pharmacol. Ther. 38 (1985) 164-170.Search in Google Scholar

405. Hecht, S. S., A. Amin, AA. Melikian, EJ. LaVoie, and D. Hoffmann: Effects of methy l and fluorine substitution on the metabolic activation and tumorigenicity of polycyclic aromatic hydrocarbons; Amer. Chem. Soc. Symp. Series 238 (1985) 85-105.Search in Google Scholar

406. Hecht, S. S., L. Radok, S. Amin, K. Huie, AA. Melikian, D. Hoffmann, J. Pataki, and R. G. Harvey: Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin; Cancer Res. 45 (1985) 1449–1452.Search in Google Scholar

407. Hoffmann, D. and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXX.] Perspectives in Cancer Research. Nicotine-derived N-nitrosamines and tobacco-related cancer: current status and future directions; Cancer Res. 45 (1985) 935–944.Search in Google Scholar

408. Hoffmann, D., S. S. Hecht, N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Tumorigenic agents in tobacco products and their uptake by chewers, smokers and nonsmokers; J. Cell. Biochem. Suppl. 9C (1985) 33.Search in Google Scholar

409. Hoffmann, D., E. J. LaVoie, and S. S. Hecht: Nicotine: a precursor for carcinogens. Cancer Lett. 26 (1985) 67–75.Search in Google Scholar

410. Hoffmann, D., A. Melikian, J. D. Adams, K. D. Brunnemann, and N. J. Haley: New Aspects of Tobacco Carcinogenesis; in: Carcinogenesis; edited by M. J. Maas et al., Raven Press, New York, NY, 1985, pp. 239–256.Search in Google Scholar

411. Hoffmann, D., A. S. Rivenson, and S. S. Hecht: The Role of Nicotine in Tobacco Carcinogenesis; in: Hommage au Professeur Rene Truhaut; edited by Comité d'organisation du jubilé scientifique du Prof. R. Truhaut, Tardy Quercy (S. A.), Cahors, France, 1985, pp. 491–495.Search in Google Scholar

412. Hoffmann, D. and E. L. Wynder: The selective reduction of cigarette smoke constituents. Proc. 1st Member Congress China Tobacco Soc., Beijing, China, 1985, pp. 234–279.Search in Google Scholar

413. LaVoie, E. J., E. A. Adams, A. Shigematsu, and D. Hoffmann: Metabolites of phenanthridine formed by rat liver homogenate; Drug Metab. Dispos. 13 (1985) 71–75.Search in Google Scholar

414. LaVoie, E. J., D. T. Coleman, J. E. Rice, N. G. Geddie, and D. Hoffmann: Tumor-initiating activity, mutagenicity, and metabolism of methylated anthracenes; Carcinogenesis 6 (1985) 1483–1488.Search in Google Scholar

415. LaVoie, E. J., A. Shigematsu, B. Mu, A. Rivenson, and D. Hoffmann: The effects of catechol on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine; Gann: Jpn. J. Cancer Res. 76 (1985) 266–271.Search in Google Scholar

416. LaVoie, E. J., A. Shigematsu, A. Rivenson, B. Mu, and D. Hoffmann: Evaluation of the effects of cotinine and nicotine-N’-oxides on the development of tumors in rats initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide; J. Natl. Cancer Inst. 75 (1985) 1075–1081.Search in Google Scholar

417. LaVoie, E. J., A. Shigematsu, P. L. Tucciarone, J. D. Adams, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXIII.] Comparison of the steam-volatile components of commercial cigarette, pipe, and chewing tobaccos; J. Agric. Food Chem. 33 (1985) 876–879.Search in Google Scholar

418. Melikian, A. A., S. S. Hecht, D. Hoffmann, J. Pataki, and R. G. Harvey: Analysis of syn- and anti-1,2-dihydroxy-3,4-epoxy-1,2,3,4-tetrahydro-5-methylchrysene-deoxyribo-nucleoside adducts by boronate chromatography; Cancer Lett. 27 (1985) 91–97.Search in Google Scholar

419. Melikian, A. A., J. M. Leszczynska, S. Amin, S. S. Hecht, D. Hoffmann, J. Pataki, and R. G. Harvey: Rates of hydrolysis and extents of DNA-binding of 5-methylchrysene dihydro-diol epoxides; Cancer Res. 45 (1985) 1990–1996.Search in Google Scholar

420. Sasson, I. M., D. T. Coleman, E. J. LaVoie, D. Hoffmann, and E. L. Wynder: Mutagens in human urine: Effects of cigarette smoking and diet; Mutat. Res. 158 (1985) 149–157.Search in Google Scholar

421. Sasson, I. M., N. J. Haley, D. Hoffmann, E. L. Wynder, D. Hellberg, and S. Nilsson: Cigarette Smoking and Neoplasia of the Uterine Cervix: Smoke Constituents in Cervical Mucus; N. Engl. J. Med. 312 (1985) 315–316.Search in Google Scholar

422. Wynder, E. L., M. T. Goodman, and D. Hoffmann: Lung Cancer Etiology: Challenges of the Future; in: Cancer of the Respiratory Tract: Predisposing Factors; edited by M. J. Maas et al., Raven Press, New York, NY, 1985, pp. 39–62.Search in Google Scholar

423. Zaridze, D. G., M. Blettner, N. N. Trapeznikov, J. P. Kuvshinov, E. G. Matiakin, B. P. Poljakov, B. K. Poddubni, S. M. Parshikova, V. I. Rottenberg, F. S. Chamrakulov, M. C. Chodjaeva, H. F. Stich, M. P. Rosin, D. I. Thurnham, D. Hoffmann, and K. D. Brunnemann: Survey of a population with a high incidence of oral and esophageal cancer; Int. J. Cancer 36 (1985) 153–158.Search in Google Scholar

424. Adams, J. D., P. L. Tucciarone, L. Genoble, K. D. Brunne-mann, and D. Hoffmann: On the anaylsis of N-nitroso compounds in tobacco and tobacco smoke by capillary GC-TEA; presented at the 40th TCRC, Knoxville, TN, No. 48.Search in Google Scholar

425. Bache, C. A., C. M. Reid, D. Hoffmann, J. D. Adams, and D. J. Lisk: Cadmium in smoke particulates of regular and filter cigarettes containing low and high cadmium concentrations; Bull. Environ. Contam. Toxicol. 36 (1986) 372–375.Search in Google Scholar

426. Brunnemann, K. D., B. Prokopczyk, D. Hoffmann, J. Nair, H. Ohshima, and H. Bartsch: Laboratory studies on oral cancer and smokeless tobacco; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 197–213.Search in Google Scholar

427. Brunnemann, K. D., R. Onrust, and D. Hoffmann: Determi-nation of volatile carbonyl compounds in tobacco headspace and tobacco smoke; presented at the 40th TCRC, Knoxville, 1986, No. 47.Search in Google Scholar

428. Connolly, G. N., D. M. Winn, S. S. Hecht, J. E. Henningfield, B. Walker Jr, and D. Hoffmann: The reemergence of smokeless tobacco; N. Engl. J. Med. 314 (1986) 1020–1027.10.1056/NEJM198604173141605Search in Google Scholar

429. Donahue, J. M., K. El-Bayoumi, S. S. Hecht, and D. Hoffmann: Aromatic amines in human urine; presented at the 77th Ann. Meeting Am. Assoc. Cancer Res., 1986, No. 373.Search in Google Scholar

430. El-Bayoumy, K., J. M. Donahue, S. S. Hecht, and D. Hoffmann: Analysis of aniline and o-toluidine in human urine; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 77–84.Search in Google Scholar

431. El-Bayoumy, K., J. M. Donahue, S. S. Hecht, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXIII.] Identification and quantitative analysis of aniline and toluidines in human urine; Cancer Res. 46 (1986) 6064–6067.Search in Google Scholar

432. Haley, N. J., D. Hoffmann, and E. L. Wynder: Uptake of Tobacco Smoke Components; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 3–19.Search in Google Scholar

433. Hecht, S. S., P. G. Foiles, S. G. Carmella, N. Trushin, A. Rivenson, and D. Hoffmann: Recent studies on the meta-bolic activation of tobacco-specific nitrosamines: Prospects for dosimetry in humans; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 245–257.Search in Google Scholar

434. Hecht, S. S., A. Rivenson, J. Braley, J. DiBello, J. D. Adams, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXII.] Induction of oral cavity tumors in F344 rats by tobacco-specific nitrosamines and snuff; Cancer Res. 46 (1986) 4162–4166.Search in Google Scholar

435. Hoffmann, D., K. D. Brunnemann, J. D. Adams, and S. S. Hecht: Laboratory studies on snuff-dipping and oral cancer; Cancer J. 1 (1986) 10–13.Search in Google Scholar

436. Hoffmann, D., N. H. Harley, I. Fisenne, J. D. Adams, and K. D. Brunnemann: [A Study of Tobacco Carcinogenesis. XXXI.] Carcinogenic agents in snuff; J. Natl. Cancer Inst. 76 (1986) 435–437.Search in Google Scholar

437. Hoffmann, D. and C. C. Harris: Mechanisms in tobacco carcinogenesis; Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 428.Search in Google Scholar

438. Hoffmann, D., S. S. Hecht, A. A. Melikian, N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Tumorigenic agents in tobacco products and their uptake by chewers, smokers and nonsmokers; in: Biochemical and Molecular Epidemiology of Cancer; edited by C. C. Harris, Alan Liss Inc., New York, NY, 1986, pp. 191–204.Search in Google Scholar

439. Hoffmann, D. and E. L. Wynder: The tumor initiator in tobacco smoke; Proc. Am. Assoc. Cancer Res., Chicago, 7 (1986) 32.Search in Google Scholar

440. Hoffmann, D. and E. L. Wynder: [A Study of Tobacco Car-cinogenesis. XXXVII.] Chemical constituents and bioacti-vity of tobacco smoke; in: Tobacco – A Major International Health Hazard, IARC Sci. Publ. 74 (1986) 145–165.Search in Google Scholar

441. Kuller, L. H., L. Garfinkel, P. Correa, N. Haley, D. Hoffmann, S. Preston-Martin, and D. Sandler: Contribution of passive smoking to respiratory cancer; Environ. Health Perspect. 70 (1986) 57–69.Search in Google Scholar

442. LaVoie, E. J., J. D. Adams, J. Reinhardt, A. Rivenson, and D. Hoffmann: Toxicity studies on clove cigarette smoke and constituents of clove: determination of the LD50 of eugenol by intratracheal instillation in rats and hamsters; Arch. Toxicol. 59 (1986) 78–81.Search in Google Scholar

443. LaVoie, E. J., J. D. Adams, J. Reinhardt, A. Rivenson, and D. Hoffmann: Comments on the toxicology of constituents in clove cigarette smoke; Arch. Toxicol. 59 (1986) 298–299.Search in Google Scholar

444. LaVoie, E. J., I. M. Sasson, D. Hoffmann, M. V. Marshall, and W. Rodgers: Mutagens in the urine of cigarette smokers; in: Mechanisms of Tobacco Carcinogenesis, Banbury Report 23; edited by D. Hoffmann and C. C. Harris, 1986, pp. 121–136.Search in Google Scholar

445. Melikian, A. A., J. M. Leszczynska, S. S. Hecht, and D. Hoffmann: Effects of the co-carcinogen catechol on benzo[a]pyrene metabolism and DNA adduct formation in mouse skin; Carcinogenesis 7 (1986) 9–15.Search in Google Scholar

446. Palladino, G., J. D. Adams, K. D. Brunnemann, N. J. Haley, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXVI.] Snuff-dipping in college students: a clinical profile; Mil. Med. 151 (1986) 342–346.Search in Google Scholar

447. Parsa, I., C. A. Foye, C. M. Cleary, and D. Hoffmann: Differences in metabolism and biological effects of NNK in human target cells; in: Mechanisms of Tobacco Carcino-genesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 233–244.Search in Google Scholar

448. Rivenson, A., D. Hoffmann, and S. S. Hecht: Local and regional tumors induced by smokeless tobacco and its components in Fischer rats; 14th Int. Cancer Cong., Buda-pest, Hungary (1986).Search in Google Scholar

449. Sepkovic, D. W., N. J. Haley, and D. Hoffmann: Elimination from the body of tobacco products by smokers and passive smokers; J. Am. Med. Assoc. 256 (1986) 863.Search in Google Scholar

450. Zaridze, D. G., M. Blettner, E. G. Matiakin, B. P. Poljakov, H. F. Stich, M. P. Rosin, D. Hoffmann, and K. D. Brunne-mann: The effect of nass use and smoking on the risk of oral leukoplakia; Cancer Detect. Prevent. 9 (1986) 435–440.Search in Google Scholar

451. Abbaspour, A., S. S. Hecht, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVII.] Synthesis of 5’-carboxy-N’-nitrosonornicotine and 5’-[14C]carboxy-N’-nitrosonornicotine; J. Org. Chem. 52 (1987) 3474–3477.Search in Google Scholar

452. Adams, J. D., K. J. O'Mara-Adams, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVI.] Toxic and carcinogenic agents in undiluted mainstream smoke and sidestream smoke of different types of cigarettes; Carcinogenesis 8 (1987) 729–731.Search in Google Scholar

453. Adams, J. D., P. Owens-Tucciarone, and D. Hoffmann: Tobacco-specific N-nitrosamines in dry snuff; Food Chem. Toxicol. 25 (1987) 245–246.10.1016/0278-6915(87)90090-1Search in Google Scholar

454. Bache, C. A., D. J. Lisk, B. S. Shane, D. Hoffmann, and J. D. Adams: Effectiveness of cigarette filter tips for reducing cadmium in relation to other mainstream smoke constituents; Drug Chem. Toxicol. 10 (1987) 189–193.Search in Google Scholar

455. Brunnemann, K. D., L. Genoble, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXV.] Identification and analysis of a new tobacco-specific N-nitrosamine, 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanol; Carcinogene-sis 8 (1987) 465–469.Search in Google Scholar

456. Brunnemann, K. D., N. J. Haley, J. D. Adams, D. W. Sepkovic, and D. Hoffmann: Model studies on the uptake of nicotine after exposure to environmental tobacco smoke (ETS); presented at the 41st TCRC, NC, 1987, No. 31.Search in Google Scholar

457. Brunnemann, K. D., A. Rivenson, J. D. Adams, S. S. Hecht, and D. Hoffmann: A study of snuff carcinogenesis; in: The Relevance of N-Nitroso Compounds to Human Cancer: Exposures and Mechanisms, IARC Sci. Publ. 84 (1987) 456–459.Search in Google Scholar

458. El-Bayoumy, K., M. O'Donnell, and D. Hoffmann: Determi-nation of aromatic amines in sidestream smoke; in: Environ-mental Carcinogens: Methods of Analysis and Exposure Measurement, IARC Sci. Publ. 81 (1987) 269–277.Search in Google Scholar

459. Gutenmann, W. H., D. J. Lisk, B. S. Shane, D. Hoffmann, and J. D. Adams: Selenium in mainstream and sidestream smoke of cigarettes containing fly ash-grown tobacco; Drug Chem. Toxicol. 10 (1987) 181–187.Search in Google Scholar

460. Haley, N. J., J. D. Adams, J. Alzofon, and D. Hoffmann: Uptake of sidestream smoke by Syrian golden hamsters; Toxicol. Lett. 35 (1987) 83–88.Search in Google Scholar

461. Haley, N. J., J. D. Adams, C. M. Axelrad, and D. Hoffmann: Sidestream smoke uptake by Syrian golden hamsters in an inhalation bioassay; in: Proc. 4th International Conf. Indoor Air ‘87, Berlin, Germany, Vol. 2 (Environmental tobacco smoke, multicomponent studies, radon, sick buildings, odors and irritants, hyperreactivities and allergies; edited by B. Seifert et al., Institute for Water, Soil and Air Hygiene) 1987, pp. 68–73.Search in Google Scholar

462. Hoffmann, D., J. D. Adams, and K. D. Brunnemann: A critical look at N-nitrosamines in environmental tobacco smoke; Toxicol. Lett. 35 (1987) 1–8.Search in Google Scholar

463. Hoffmann, D., J. D. Adams, D. Lisk, I. Fisenne, and K. D. Brunnemann: [A Study of Tobacco Carcinogenesis. XXXIX.] Toxic and carcinogenic agents in dry and moist snuff; J. Natl. Cancer Inst. 79 (1987) 1281–1286.Search in Google Scholar

464. Hoffmann, D., K. D. Brunnemann, N. J. Haley, D. W. Sepko-vic, and J. D. Adams: Nicotine uptake by nonsmokers exposed to passive smoking under controlled conditions and the elimination of cotinine; in: Proc. 4th International Conf. Indoor Air ‘87, Berlin, Germany, Vol. 2, (Environmental tobacco smoke, multicomponent studies, radon, sick buildings, odors and irritants, hyperreactivities and allergies; edited by B. Seifert et al., Institute for Water, Soil and Air Hygiene), 1987, pp. 13–17.Search in Google Scholar

465. Hoffmann, D. and I. Hoffmann: Significance of Exposure to Sidestream Tobacco Smoke; in: Environmental Carcinogens - Methods of Analysis and Exposure Measurement. Vol. 9: Passive Smoking, IARC Sci. Publ. 81 (1987) 3–10.Search in Google Scholar

466. Hoffmann, D., E. J. LaVoie, and S. S. Hecht: Chemical fractionation and bioassay of complex mixtures: studies in tobacco carcinogenesis; in: Health and Environmental Research on Complex Organic Mixtures; edited by R. H. Gray et al., Battelle, Pacific Northwest Laboratory, Rich-land, WA, 1987, pp. 151–165.Search in Google Scholar

467. Hoffmann, D., E. L. Wynder, S. S. Hecht, K. D. Brunnemann, E. J. LaVoie, and N. J. Haley: Chemical carcinogens in tobacco; in: Cancer Risks: Strategies for Elimination; edited by P. Bannasch, Springer-Verlag, Berlin, 1987, pp. 101–113.10.1007/978-3-642-71843-4_9Search in Google Scholar

468. Prokopczyk, G., J. D. Adams, E. J. LaVoie, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXIV.] Effect of snuff and nicotine on DNA methylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; Carcinoge-nesis 8 (1987) 1395–1397.Search in Google Scholar

469. Prokopczyk, B., K. D. Brunnemann, P. Bertinato, and D. Hoffmann:The role of N- (nitrosomethylamino)propionitrile in betel-quid carcinogenesis; IARC Monogr. 84 (1987) 470–473.Search in Google Scholar

470. Prokopczyk, B., A. Rivenson, P. Bertinato, K. D. Brunnemann, and D. Hoffmann: [A study of betel quid carcinogenesis. V.] 3-(Methylnitrosamino)propionitrile: occurrence in saliva of betel quid chewers, carcinogenicity and DNA methylation in F344 rats; Cancer Res. 47 (1987) 467-471.Search in Google Scholar

471. Schiffmann, M. H., NJ. Haley, J. S. Felton, A. W. Andrews, R. A. Kaslow, W. D. Lancaster, RJ. Kurman, LA. Brinton, L. B. Lannom, and D. Hoffmann: Biochemical epidemiology of cervical neoplasia: measuring cigarette smoke constitu-ents in the cervix; Cancer Res. 47 (1987) 3886-3888.Search in Google Scholar

472. Tucciarone, P. L., J. D. Adams, E. L. LaVoie, M. Kagan, and D. Hoffmann: Quantitative analyses of steam distillates and aqueous extracts of commercial smokeless tobaccos; presented at the 41st TCRC, 1987, Greensboro, NC, No. 11.Search in Google Scholar

473. Brunnemann, K. D., M. R. Kagan, and D. Hoffmann: Analy-sis of selected gas phase components by GC-MSD; pre-sented at the 42nd TCRC, Lexington, KY, 1988, No. 18.Search in Google Scholar

474. Brunnemann, K. D., A. Rivenson, A. Czech, EJ. LaVoie, and D. Hoffmann: Isolation, identification, and bioassay of the tobacco-specific N-nitrosamine 4-methylnitrosamino-(3-pyridyl)-1-butanol; Proc. Am. Assoc. Cancer Res. 29 (1988) No. 332.Search in Google Scholar

475. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: Identification and analy sis of nicotine-derived N-nitrosamino acid and other nitrosamino acids in tobacco; presented at the 42nd TCRC, Lexington, KY, 1988, No. 41.Search in Google Scholar

476. Haley, N. J., D. W. Sepkovic, E. Louis, and D. Hoffmann: Absorption and elimination by smokers, nonsmokers, and chewers of nicotine gum; in: The Pharmacology of Nicotine; edited by M. J. Rand and K. Thurau, IRL Press, Washington, DC, 1988, pp. 20-21.Search in Google Scholar

477. Hecht, S. S., A. Abbaspour, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLII. Bioassay in A/J mice of some structural analogues of tobacco-specific nitrosamines; Cancer Lett. 42 (1988) 141-145.Search in Google Scholar

478. Hecht, S. S., S. G. Carmella, N. Trushin, T. E. Spratt, P. G. Foiles, and D. Hoffmann: Approaches to the development of assays for interaction of tobacco specific nitrosamines with hemoglobin and DNA; in: Methods for Detecting DNA Damaging Agents in Humans: Applications in Cancer Epidemiology and Prevention, IARC Sci. Publ. 89 (1988) 121-128.Search in Google Scholar

479. Hecht, S. S. and D. Hoffmann: Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke; Carcinogenesis 9 (1988) 875-884.Search in Google Scholar

480. Hellberg, D., S. Nilsson, N. J. Haley, D. Hoffmann, and E. Wynder: Smoking and cervical intraepithelial neoplasia -nicotine and continine in serum and cervical mucus in smokers and nonsmokers; Am. J. Obstet. Gynecol. 158 (1988) 910-913.Search in Google Scholar

481. Hoffmann, D.: Krank durch Passivrauchen? Oral presentation held on the Symposium ‘Krank durch Passivrauchen?’ Vienna, Austria, 1988, in: Transcription of a live recording, pp. 41–45.Search in Google Scholar

482. Hoffmann, D., J. D. Adams, EJ. LaVoie, and S. S. Hecht: Biochemistry, pharmacokinetics and carcinogenicity of nicotine-derived nitrosamines; in: Pharmacology of Nicotine; edited by M. J. Rand and K. Thurau, IRL Press, Oxford, UK, 1988, pp. 43-60.Search in Google Scholar

483. Hoffmann, D., K. D. Brunnemann, and S. Venitt: Carcino-genic nitrosamines in oral snuff; Lancet 331 (1988) 1232.Search in Google Scholar

484. Hoffmann, D. and S. S. Hecht: Smokeless tobacco and cancer; ISI Atlas of Science. Pharmacology 2 (1988) 46-52.Search in Google Scholar

485. Prokopczyk, B., P. Bertinato, and D. Hoffmann: Cyano-ethylation of DNA in vivo by 3-(methy lnitrosamino)proprionitrile, an areca-derived carcinogen; Cancer Res. 48 (1988) 6780–6784.Search in Google Scholar

486. Prokopczyk, B., P. Bertinato, and D. Hoffmann: Synthesis and kinetics of decomposition of 7-(2-cyanoethyl)guanine and O6-(2-cyanoethyl)guanine, markers for reaction of acrylonitrile and 3-(methylnitrosamino)propionitrile with DNA; Carcinogenesis 9 (1988) 2125–2128.Search in Google Scholar

487. Rivenson, A., S. S. Hecht, and D. Hoffmann: Observations on lung tumors arising from metaplastic squamous epithe-lium in rats treated chronically with the tobacco-specific N-nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK); Proc. Am. Assoc. Cancer Res. 29 (1988) No. 342.Search in Google Scholar

488. Rivenson, A., D. Hoffmann, B. Prokopczyk, S. Amin, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XLI.] Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines; Cancer Res. 48 (1988) 6912–6917.Search in Google Scholar

489. Sepkovic, D. W., N. J. Haley, and D. Hoffmann: Use of Urinary Cotinine to Estimate Exposure to Tobacco Smoke -Reply; JAMA 259 (1988) 1808–1809.Search in Google Scholar

490. Anderson, L. M., S. S. Hecht, D. E. Dixon, L. F. Dove, R. M. Kovatch, S. Amin, D. Hoffmann, and J. M. Rice: Evaluation of the transplacental tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice; Cancer Res. 49 (1989) 3770–3775.Search in Google Scholar

491. Brunnemann, K. D., R. Feng, and D. Hoffmann: Pyrolysis studies of selected nitrosamino acids in cigarettes; presented at the 43rd TCRC, Richmond, VA, 1989, No. 44.Search in Google Scholar

492. Brunnemann, K. D., M. R. Kagan, J. E. Cox, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVII.] Determination of benzene, toluene and 1,3-butadiene in cigarette smoke by GC-MSD; Exp. Pathol. 37 (1989) 108–113.Search in Google Scholar

493. Djordjevic, M. V., C. W. Sigountos, K. D. Brunnemann, and D. Hoffmann: On the formation of 4-(methylnitrosamino)-4-(3-pyridyl) butyric acid in tobacco and tobacco smoke; presented at the 43rd TCRC, Richmond, VA, 1989, No. 27.Search in Google Scholar

494. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XLIII.] Identification and analysis of a nicotine-derived N-nitrosamino acid and other nitrosamino acids in tobacco; Carcinogenesis 10 (1989) 1725–1731.Search in Google Scholar

495. Haley, N. J., D. W. Sepkovic, K. D. Brunnemann, and D. Hoffmann: Biomarkers for Assessing Environmental Tobacco Smoke Update; in: Combustion Processes and the Quality of the Indoor Environment; edited by J. P. Harper, Air and Waste Management Association, Pittsburgh, PA, 1989, pp, 1–13.Search in Google Scholar

496. Haley, N. J., D. W. Sepkovic, and D. Hoffmann: Elimination of cotinine from body fluids: disposition in smokers and nonsmokers; Am. J. Public Health 79 (1989) 1046–1048.Search in Google Scholar

497. Hecht, S. S. and D. Hoffmann: The relevance of tobacco-specific nitrosamines to human cancer; Cancer Surv. 8 (1989) 273–294.Search in Google Scholar

498. Hoffmann, D.: Nicotine - a tobacco-specific precursor for carcinogens; in: Nicotine, Smoking, and the Low-Tar Programme; edited by N. Wald and P. Frogatt, Oxford University Press, Oxford, UK, 1989, pp. 24–40.Search in Google Scholar

499. Hoffmann, D., K. D. Brunnemann, and I. Hoffmann: Signifi-cance of Benzene in Tobacco Carcinogenesis; in: Benzene: Occupational and Environmental Hazards - Scientific Update; edited by M. A. Mehlman, Princeton Scientific Publ. Co., Princeton, NY, 1989, pp. 99–112.Search in Google Scholar

500. Hoffmann, D. and S. S. Hecht: Advances in Tobacco Carcinogenesis; in: Chemical Carcinogenesis and Mutagene-sis, Springer Handbook of Experimental Pharmacology -edited by C. S. Cooper and P. L. Grover, Springer Verlag, New York, NY, 1989, pp. 63–102.10.1007/978-3-642-74775-5_3Search in Google Scholar

501. Hoffmann, D. and I. Hoffmann: On the reduction of nicotine in cigarette smoke; in: Nicotine, Smoking, and the Low-Tar Programme; edited by N. Wald and P. Froggatt, Oxford University Press, Oxford, UK, 1989, pp. 200–211.Search in Google Scholar

502. LaVoie, E. J., P. Tucciarone, M. Kagan, J. D. Adams, and D. Hoffmann: Analysis of steam distillates and aqueous extracts of smokeless tobacco; J. Agric. Food Chem. 37 (1989) 154–157.Search in Google Scholar

503. Melikian, A. A., K. Bagheri, B. F. Goldin, and D. Hoffmann: Catechol-induced alterations in metabolic activation and binding of enantiomeric and racemic 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene to DNA in mouse skin; Carcinogenesis 10 (1989) 1863–1870.Search in Google Scholar

504. Melikian, A. A., K. Bagheri, S. S. Hecht, and D. Hoffmann: Metabolism of benzo[a]pyrene and 7-?,8-?-dihydroxy-9-?,10-?-epoxy -7,8,9,10-tetrahy dr ob en zo [a]pyrene in lung and liver of newborn mice; Chem. -Biol. Interact. 69 (1989) 245–257.Search in Google Scholar

505. Melikian, A. A., S. S. Hecht, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XL.] Mechanistic studies of tobacco carcinogenesis in mouse epidermis and lung tissues; in: Skin Carcinogenesis: Mechanisms and Human Rele-vance; edited by T. J. Slaga et al., A. R. Liss, Inc., New York, NY, 1989, pp. 331–345.Search in Google Scholar

506. Melikian, A. A., K. G. Jordan, J. Braley, J. Rigotty, C. L. Meschter, S. S. Hecht, and D. Hoffmann: Effects of catechol on the induction of tumors in mouse skin by 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrenes; Carcinogenesis 10 (1989) 1897–1900.Search in Google Scholar

507. Rivenson, A., M. V. Djordjevic, S. Amin, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLIV. Bioassay in A/J mice for some N-nitrosamines; Cancer Lett. 47 (1989) 111–114.Search in Google Scholar

508. Brunnemann, K. D., J. E. Cox, M. R. Kagan, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCIV.] Analysis of selected environmental tobacco smoke compo-nents in indoor air by thermal desorption-GC-MS; presented at the CORESTA Symposium, Kallithea, Greece, 1990, No. S10; in: Proc. CORESTA Symposium, Kallithea, Greece, 1990, pp. 100–107.Search in Google Scholar

509. Brunnemann, K. D., J. E. Cox, M. R. Kagan, and D. Hoffmann: Application of thermal desorption for the analysis of environmental tobacco smoke (ETS); presented at the 44th TCRC, Winston-Salem, NC, 1990, No. 27.Search in Google Scholar

510. Brunnemann, K. D. and D. Hoffmann: Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke; J. Cancer Res. Clin. Oncol. 116 (Suppl. Pt. 2) (1990) 1087.Search in Google Scholar

511. Brunnemann, K. D., M. R. Kagan, J. E. Cox, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVIII.] Analysis of 1,3-butadiene and other selected gas phase components in cigarette mainstream and sidestream smoke by gas chromatography-mass selective detection; Carcinoge-nesis 11 (1990) 1863–1868.Search in Google Scholar

512. Djordjevic, M. V., D. Desai, C. Sigountos, K. D. Brunne-mann, and D. Hoffmann: Mechanistic studies on the formation of 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid and other tobacco-specific nitrosamines during tobacco processing; presented at the 44th TCRC, Winston-Salem, NC, 1990, No. 43.10.1021/jf00001a043Search in Google Scholar

513. Djordjevic, M. V., C. W. Sigountos, K. D. Brunnemann, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCIII.] Tobacco-specific nitrosamine delivery in the mainstream smoke of high- and low-yield cigarettes smoked with varying puff volumes; presented at the CORESTA Symposium, Kallithea, Greece, 1990, No. S04; in: Proc. CORESTA Symp. Kallithea, Greece, 1990, pp. 54–62.Search in Google Scholar

514. Haley, N. J., D. W. Sepkovic, K. D. Brunnemann, and D. Hoffmann: ETS uptake in nonsmokers after exposure to high-yield and low-yield cigarettes; in: Proceedings of the 5th International Conf. on Indoor Air Quality and Climate, Toronto, Canada, Vol. 2, 1990, pp. 183-188.Search in Google Scholar

515. Hoffmann, D., S. Amin, K. D. Brunnemann, B. Prokopczyk, A. Rivenson, and S. S. Hecht: Tobacco-specific N-nitros-amines: analysis, bioassays and biochemical studies; in: N-Nitroso Compounds: Biology and Chemistry; edited by S. V. Bhide and K. V. K. Rao, Omega Scientific Publishers, New Delhi, India, 1990, pp. 59-79.Search in Google Scholar

516. Hoffmann, D., NJ. Haley, and E. L. Wynder: [A Study of Tobacco Carcinogenesis. XLV.] Laboratory studies on the association of cigarette smoking with cancer of the uterine cervix; J. Smoking Rel. Dis. 1 (1990) 15-23.Search in Google Scholar

517. Melikian, A. A., K. Bagheri, and D. Hoffmann: Oxidation and DNA binding of (+)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in mouse epidermis in vivo and effects of co-administration of catechol; Cancer Res. 50 (1990) 1795-1799.Search in Google Scholar

518. Miyashita, M., J. C. Willey, K. Sasajima, J. F. Lechner, EJ. LaVoie, D. Hoffmann, M. Smith, B. F. Trump, and CC. Harris: Differential effects of cigarette smoke condensate and its fractions on cultured normal and malignant human bronchial epithelial cells; Exp. Pathol. 38 (1990) 19-29.Search in Google Scholar

519. Murphy, S. E., A. Palomino, S. S. Hecht, and D. Hoffmann: Dose response study of DNA and hemoglobin adduct formation by 4-(methylnitrosamino)-1-(3-pyridyl)-1 buta-none in F344 rats; Cancer Res. 50 (1990) 5446-5452.Search in Google Scholar

520. Prokopczyk, B., A. Sharma, J. E. Cox, K. D. Brunnemann, and D. Hoffmann: Application of supercritical fluid extraction for the analysis of selected components in chewing tobaccos; presented at the 44th TCRC, Winston-Salem, NC, 1990, No. 69.Search in Google Scholar

521. Anderson, L. M., S. S. Hecht, R. M. Kovatch, S. Amin, D. Hoffmann, and J. M. Rice: Tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in infant mice; Cancer Lett. 58 (1991) 177-181.Search in Google Scholar

522. Brunnemann, K. D., M. V. Djordjevic, R. Feng, and D. Hoffmann: Analysis and pyrolysis of some N-nitrosamino acids in tobacco and tobacco smoke; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins, IARC Sci. Publ. 105 (1991) 477-481.Search in Google Scholar

523. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCIII.] Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke; Crit. Rev. Toxicol. 21 (1991) 235-240.Search in Google Scholar

524. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCVII.] Analytical studies on N-nitros-amines in tobacco and tobacco smoke; presented at the 45th TCRC, Asheville, NC, 1991, No. 3; in: Rec. Adv. Tobacco Sci. 17 (1991) 71-112.Search in Google Scholar

525. Brunnemann, K. D. and D. Hoffmann: Methods of analysis for tobacco-specific N-nitrosamines in indoor air; presented at the 45th TCRC, Asheville, NC, 1991, No. 50.Search in Google Scholar

526. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XC] Decreased concentrations of N-nitrosodiethanolamine and N-nitrosomorpholine in commer-cial tobacco products; J. Agric. Food Chem. 39 (1991) 207-208.Search in Google Scholar

527. Djordjevic, M. V., J. Krzeminski, K. D. Brunnemann, and D. Hoffmann: Identification and quantitative analysis of new N-nitrosamino acids in snuff tobacco; presented at the 45th TCRC, Asheville, NC, 1991, No. 16.Search in Google Scholar

528. Djordjevic, M. V., CM. Sigountos, K. D. Brunnemann, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXIX.] Formation of 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid in vitro and in mainstream cigarette smoke; J. Agric. Food Chem. 39 (1991) 209-213.Search in Google Scholar

529. Djordjevic, M. V., C. W. Sigountos, D. Hoffmann, K. D. Brunnemann, M. R. Kagan, L. P. Bush, R. D. Safaev, GA. Belitsky, and D. Zaridze: Chemical Studies on Tobacco Smoke. XCI. Assessment of major carcinogens and alkaloids in the tobacco and mainstream smoke of USSR cigarettes; Int. J. Cancer 47 (1991) 348-351.Search in Google Scholar

530. Hecht, S. S., NJ. Haley, and D. Hoffmann: Monitoring exposure to tobacco products by measurement of nicotine metabolites and derived carcinogens; in: Molecular Dosime-try and Human Cancer: Analytical, Epidemiological, and Ethical Considerations; edited by J. D. Groopman and P. L. Skipper, CRC Press, Boca Raton, FL, 1991, pp. 325-361.Search in Google Scholar

531. Hecht, S. S. and D. Hoffmann: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a nicotine-derived tobacco-specific nitrosamine, and cancer of the lung and pancreas in humans; in: Origin of Human Cancer: A Comprehensive Review, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1991, pp. 745-755.Search in Google Scholar

532. Hecht, S. S. and D. Hoffmann: N-Nitroso compounds and tobacco-induced cancer in man; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins, IARC Sci. Publ. 105 (1991) 54-61.Search in Google Scholar

533. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: [Chemical Studies on Tobacco Smoke. XCII.] New brands of oral snuff. (Brief Communication); Food Chem. Toxicol. 29 (1991) 65-68.Search in Google Scholar

534. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: On the control of toxic substances in smokeless tobacco; J. Smoking Related Dis. 3 (1991) 165-172.Search in Google Scholar

535. Hoffmann, D., NJ. Haley, M. Djordjevic, K. D. Brunnemann, and S. S., Hecht: Biomarkers of exposure to tobacco products; in: Human Carcinogen Exposure: Biomonitoring and Risk Assessment; edited by R. C Garner et al, IRL Press, Oxford, UK, 1991, pp. 275-283.Search in Google Scholar

536. Hoffmann, D., I. Hoffmann, and E. L. Wynder: Lung cancer and the changing cigarette; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins; IARC Sci. Publ. 105 (1991) 449–459.Search in Google Scholar

537. Hoffmann, D., AA. Melikian, and K. D. Brunnemann: Studies in tobacco carcinogenesis; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins; IARC Sci. Publ. 105 (1991) 482–484.Search in Google Scholar

538. Hoffmann, D., A. Rivenson, F. -L. Chung, and S. S. Hecht: Relevance of Nicotine-derived N-Nitrosamines in Tobacco Carcinogenesis; in: Effects of nicotine on biological sys-tems; edited by F. Adlkofer and K. Thurau, Birkhäuser Publ, Boston, MA, 1991, pp. 89-101.10.1007/978-3-0348-7457-1_13Search in Google Scholar

539. Hoffmann, D., A. Rivenson, F. -L. Chung, and S. S. Hecht: Nicotine-derived N-nitrosamines (TSNA) and their rele-vance in tobacco carcinogenesis; Crit. Rev. Toxicol. 21 (1991) 305-311.Search in Google Scholar

540. Matsukura, N., J. Willey, M. Miyashita, B. Taffe, D. Hoffmann, C. Waldren, T. T. Puck, and CC. Harris: Detection of direct mutagenicity of cigarette smoke condensate in mammalian cells; Carcinogenesis 12 (1991) 685-689.Search in Google Scholar

541. Melikian, A. A., K. Bagheri, S. S. Hecht, and D. Hoffmann: Comparative metabolism and disposition of benzo[a]pyrene and 7-|3,8-a-dihydroxy-9-a,10-a-epoxy-7,8,9,10-tetrahydro-benzo[a]pyrene in mouse epidermis and in the lungs of newborn mice in vivo; in: Polynuclear Aromatic Hydrocar-bons: Measurements, Means, and Metabolism; edited by M. Cooke et al, Battelle Press, Columbus, OH, 1991, pp. 571-581.Search in Google Scholar

542. Mitacek, EJ., K. D. Brunnemann, A. P. Polednak, D. Hoffmann, and M. Suttajit: [Chemical Studies on Tobacco Smoke. XCV.] Composition of popular tobacco products in Thailand, and its relevance to disease prevention; Prev. Med. 20 (1991) 764-773.Search in Google Scholar

543. Prokopczyk, B., D. Hoffmann, J. E. Cox, M. V. Djordjevic, and K. D. Brunnemann: Application of supercritical fluid extraction for the analysis of tobacco-specific N-nitros-amines in tobacco; presented at the 45th TCRC, Asheville, NC, 1991, No. 15.Search in Google Scholar

544. Prokopczyk, B., A. Rivenson, and D. Hoffmann: A Study of Betel Quid Carcinogenesis IX. Comparative carcinogenicity of 3-(methylnitrosamino)propionitrile and 4-(methylnitros-amino)-1-(3-pyridyl)-1-butanone upon local application to mouse skin and rat oral mucosa; Cancer Lett. 60 (1991) 153–157.Search in Google Scholar

545. Rivenson, A., S. S. Hecht, and D. Hoffmann: Carcinogenicity of tobacco-specific N-nitrosamines (TSNA): the role of the vascular network in the selection of target organs; Crit. Rev. Toxicol. 21 (1991) 255–264.Search in Google Scholar

546. Rivenson, A. and D. Hoffmann: Extensive spontaneous occlusive arteriosclerosis of the lingual arteries in Fischer rats, a model for the study of human occlusive arteriosclero-sis of medium- and small-sized arteries; Artery 18 (1991) 150–162.Search in Google Scholar

547. Sharma, A. K., B. Prokopczyk, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCII.] Supercritical fluid extraction of moist snuff; J. Agric. Food Chem. 39 (1991) 508–510.Search in Google Scholar

548. Zaridze, D. G., R. D. Safaev, G. A. Belitsky, K. D. Brunne-mann, and D. Hoffmann: Carcinogenic substances in Soviet tobacco products; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins, IARC Sci. Publ. 105 (1991) 485–488.Search in Google Scholar

549. Brunneman, K. D., J. E. Cox, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCVIII.] Analysis of tobacco-specific N-nitrosamines in indoor air; Carcinogenesis 13 (1992) 2415–2418.Search in Google Scholar

550. Brunneman, K. D., J. E. Cox, Y. Liu, and D. Hoffmann: Analysis of volatile and tobacco-specific N-nitrosamines in tobacco smoke by conventional method and by supercritical fluid extraction; presented at the 46th TCRC, Montreal, Canada, 1992, No. 22.Search in Google Scholar

551. Brunnemann, K. D. and D. Hoffmann: Chemical composition of smokeless tobacco products; in: Smokeless tobacco or health: An international perspective; edited by D. R. Shop-land et al., Smoking and Tobacco Control Monogr. 2, NCI, Bethesda, MD, 1992, pp. 96–108.Search in Google Scholar

552. Brunnemann K. D. and D. Hoffmann: Analysis of tobacco-specific N-nitrosamines in tobacco and tobacco smoke; presented at the 204th Natl. Meeting Am. Chem. Soc., Washington, DC, 1992, No. 161.Search in Google Scholar

553. Brunnemann, K. D., B. Prokopczyk, M. V. Djordjevic, J. E. Cox, and D. Hoffmann: The use of supercritical fluid extraction for the analysis of tobacco-specific N-nitros-amines in tobacco and in tobacco smoke; presented at the CORESTA Congress, Jerez de la Frontera, 1992, No. ST10.Search in Google Scholar

554. Brunnemann, K. D., A. Rivenson, S. C. Cheng, V. Saa, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLVII. Bioassays of vinylpyridines for genotoxicity and for tumori-genicity in A/J mice; Cancer Lett. 65 (1992) 107–113.Search in Google Scholar

555. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: The occurence of N-nitrosamino acids in commercial tobacco products and effect of storage conditions on their levels; presented at the 46th TCRC, Montreal, Canada, 1992, No. 23.Search in Google Scholar

556. Djordjevic, M. V., D. Hoffmann, K. D. Brunnemann, L. P. Bush: Effect of storage conditions on the levels of tobacco-specific nitrosamines, alkaloids and nitrite in US commer-cial moist snuff; presented at the CORESTA Congress, Jerez de la Frontera, 1992, No. ST17.Search in Google Scholar

557. Djordjevic, M. V., J. Krzeminski, K. D. Brunnemann, and D. Hoffmann: Characterization of N-nitrosamino acids in tobacco products and assessment of their carcinogenic potential; presented at the 204th Natl. Meeting, Am. Chem. Soc., Washington, DC, 1992, No. 160.Search in Google Scholar

558. Hoffmann, D., K. D. Brunnemann, I. Hoffmann, A. Riven-son, and S. S. Hecht: Advances in Tobacco Carcinogenesis. II. Cigarette smoke; in: Control of Tobacco-related Cancers and Other Diseases; edited by P. C. Gupta et al, Oxford University Press, Bombay, India, 1992, pp. 205-216.Search in Google Scholar

559. Hoffmann, D., S. S. Hecht, and E. L. Wynder: Cancer of the upper aerodigestive tract: environmental factors and prevention; J. Tobacco Rel. Dis. 3 (1992) 109-129.Search in Google Scholar

560. Hoffmann, D., A. Rivenson, and S. S. Hecht: Carcinogenesis of Smokeless Tobacco; in: Smokeless tobacco or health: An international perspective; edited by D. R. Shopland et al, Smoking and Tobacco Control Monogr. 2, NCI, Bethesda, MD, 1992, pp. 109-118.Search in Google Scholar

561. Hoffmann, D., A. Rivenson, B. Prokopczyk, K. D. Brunne-mann, S. G. Carmella, and I. Hoffmann: Advances in Tobacco Carcinogenesis I. Smokeless tobacco and betel quid; in: Control of Tobacco-Related Cancers and Other Diseases; edited by P. C. Gupta et al, Oxford University Press, Bombay, India, 1992, pp. 193-204.Search in Google Scholar

562. Hoffmann, D., A. Rivenson, E. L. Wynder, and S. S. Hecht: Formation of tobacco-specific N-nitrosamines, their carcino-genicity, and the role of dietary fat in their carcinogenicity; presented at the 204th Natl. Meeting, Am. Chem. Soc, Washington, DC, 1992, No. 119.Search in Google Scholar

563. Koppang, N., A. Rivenson, A. Reith, H. K. Dahle, Ö. Eversen, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLVIII. Carcinogenicity of N’-nitrosonornico-tine in mink (Mustela vison); Carcinogenesis 13 (1992) 1957-1960.Search in Google Scholar

564. Murphy, S. E., S. Amin, K. Coletta, and D. Hoffmann: Rat liver metabolism of benzo[b]naphtho[2,1-d]thiophene; Chem. Res. Toxicol. 5 (1992) 491–495.Search in Google Scholar

565. Nishikawa, A., B. Prokopczyk, A. Rivenson, E. Zang, and D. Hoffmann: A Study of Betel Quid Carcinogenesis VIII. Carcinogenicity of 3-(methylnitrosamino)propionaldehyde in F344 rats; Carcinogenesis 13 (1992) 369-372.Search in Google Scholar

566. Prokopczyk, B., D. Hoffmann, J. E. Cox, M. V. Djordjevic, and K. D. Brunnemann: [Chemical Studies on Tobacco Smoke. XCVI.] Supercritical fluid extraction in the determi-nation of tobacco-specific N-nitrosamines in smokeless tobacco; Chem. Res. Toxicol. 5 (1992) 336-340.Search in Google Scholar

567. Prokopczyk, B., M. Wu, J. E. Cox, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XLVI.] Bioavailability of tobacco-specific N-nitrosamines to the snuff dipper; Carcinogenesis 13 (1992) 863-866.Search in Google Scholar

568. Safaev, R., G. A. Belitskii, TA. Licheva, I. A. Khitrovo, S. Y. Fukhs, L. V. Krivosheyeva, D. Hoffmann, K. D. Brunnemann, and M. V. Djordjevic: The effect of cigarette filter modification on the content of chemical carcinogens in cigarette smoke and genotoxicity of condensate; Eksp. Onkol. 14 (1992) 24-27.Search in Google Scholar

569. Safaev, R., D. G. Zaridze, G. A. Belitskii, M. V. Djordjevic, D. Hoffmann, K. D. Brunnemann, Y. A. Perezhogina, N. N. Sokolskaya, A. Goginasvili, and Y. Khesina: Carcinogenic substances in the tobacco and smoke of cigarettes: Polynuclear aromatic hydrocarbons, metals, pesticides; Eksp. Onkol. 14 (1992) 25-29.Search in Google Scholar

570. Brunnemann, K. D., J. E. Cox, and D. Hoffmann: Determination of cadmium in cigarette smoke and its possible role as biomarker; presented at the 47th TCRC, Gatlinburg, TN, 1993, No. 20.Search in Google Scholar

571. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: The need for regulation of carcinogenic N-nitrosamines in oral snuff; Food Chem. Toxicol. 31 (1993) 497-501.Search in Google Scholar

572. Djordjevic, M. V., J. Fan, K. D. Brunnemann, and D. Hoffmann: In vitro nitrosation of nicotine and some of its metabolites under phy siological conditions; presented at the 47th TcRC, Gatlinburg, TN, 1993, No. 12.Search in Google Scholar

573. Djordjevic, M. V., J. Fan, L. P. Bush, K. D. Brunnemann, and D. Hoffmann: Effects of storage conditions on levels of tobacco-specific N-nitrosamines and N-nitrosamino acids in US moist snuff; J. Agric. Food, Chem. 41(1993) 1790-1794.Search in Google Scholar

574. Hecht, S. S., S. G. Carmella, S. E. Murphy, S. Akerkar, K. D. Brunnemann, and D. Hoffmann: A Tobacco-specific Lung Carcinogen in the Urine of Men Exposed to Cigarette Smoke; New Engl. J. Med. 329 (1993) 1543-1546.Search in Google Scholar

575. Hoffmann, D.: Analysis of toxic smoke constituents; in: U. S. Consumer Product Safety Commission. Fire Safe Cigarette Act of 1990. Toxicity Testing. Vol. 5; edited by B. C. Lee, Washington, DC, 1993, pp. D1-D38.Search in Google Scholar

576. Hoffmann, D: In vivo bioassays for carcinogenicity. U. S. Consumer Product Safety Commission. Fire Safe Cigarette Act of 1990. Toxicity Testing. Vol. 5; edited by B. C. Lee, Washington, DC, 1993, pp. F1-F17.Search in Google Scholar

577. Hoffmann, D., M. V. Djordjevic, A. Rivenson, E. Zang, D. Desai, and S. Amin: A Study of Tobacco Carcinogenesis. LI. Relative potencies of tobacco-specific N-nitrosamines as inducers of lung tumors in A/J mice; Cancer Lett. 71 (1993) 25-30.Search in Google Scholar

578. Hoffmann, D. and I. Hoffmann: Tobacco smoke as a respiratory carcinogen; in: Prevention of Respiratory Disease; edited by A. Hirsch et al., Marcel Dekker Inc., New York, NY, Vol. 68, 1993, pp. 497-532.Search in Google Scholar

579. Hoffmann, D., A. Rivenson, R. Abbi, and E. L. Wynder: A Study of Tobacco Carcinogenesis [L.]: Effect of the fat content of the diet on the carcinogenic activity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats; Cancer Res. 53 (1993) 2758-2761.Search in Google Scholar

580. Hoffmann, D., A. Rivenson, F. -L. Chung, and E. L. Wynder: Potential inhibitors of tobacco carcinogenesis; Ann. NY Acad. Sci. 686 (1993) 140-160.Search in Google Scholar

581. Hoffmann, D., A. Rivenson, S. E. Murphy, F. -L. Chung, S. Amin, and S. S. Hecht: Cigarette smoking and adenocarci-noma of the lung: the relevance of nicotine-derived N-nitrosamines; J. Smoking Related Dis. 4 (1993) 165-189.Search in Google Scholar

582. Melikian, AA., A. K. Prahalad, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XLIX.] Urinary trans, trans-muconic acid as an indicator of exposure to benzene in cigarette smokers; Cancer Epidemiol. Biomarkers Prev. 2 (1993) 47-51.Search in Google Scholar

583. Brunnemann, K. D. and D. Hoffmann: Analysis of tobacco-specific nitrosamines in tobacco and tobacco smoke; in: Nitrosamines and Related N-Nitroso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and CJ. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 369-371.Search in Google Scholar

584. Brunnemann, K. D. and D. Hoffmann: Analysis of selected mainstream smoke components of low ignition propensity cigarettes; presented at the 48th TCRC, Greenboro, NC, 1994, No. 54.Search in Google Scholar

585. Brunnemann, K. D., D. Hoffmann, CG. Gairola, and B. C. Lee: [Chemical Studies on Tobacco Smoke. XCIX.] Low ignition propensity cigarettes: smoke analysis for carcino-gens and testing for mutagenic activity of the smoke particu-late matter; Food Chem. Toxicol. 32 (1994) 917-922.Search in Google Scholar

586. Djordjevic, M. V., J. Fan, and D. Hoffmann: Chlorinated pesticide residues in tobacco products: analysis based on supercritical fluid extraction; presented at the 48th TCRC, Greenboro, NC, 1994, No. 49.Search in Google Scholar

587. Djordjevic, M. V., J. Fan, J. Krzeminski, K. D. Brunnemann, and D. Hoffmann: Characterization of N-nitrosamino acids in tobacco products and assessment of their carcinogenic potential; in: Nitrosamines and Related N-Nitroso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and CJ. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 367-368.Search in Google Scholar

588. Djordjevic, M. V., D. Hoffmann, J. Fan, B. Prokopczyk, M. L. Citron, and S. D. Stellman: Assessment of chlorinated pesticide and polychlorinated biphenols in adipose breast tissue using a supercritical fluid extraction method; Carcinogenesis 15 (1994) 2581-2585.Search in Google Scholar

589. Hecht, S. S., S. E. Murphy, and D. Hoffmann: Tobacco-specific lung carcinogen and exposure to passive smoking; New Eng. J. Med. 330 (1994) 1016–1017.Search in Google Scholar

590. Hoffmann, D., K. D. Brunnemann, B. Prokopczyk, and M. V. Djordjevic: Tobacco-specific N-nitrosamines and areca-derived N-nitrosamines: chemistry, biochemist ry, carcinoge-nicity and relevance to humans; J. Toxicol. Environ. Health 41 (1994) 1–52.Search in Google Scholar

591. Hoffmann, D. and I. Hoffmann: Recent developments in smoking related cancer research; J. Smoking Rel. Disord. 5 (1994) 77–93.Search in Google Scholar

592. Hoffmann, D. and I. Hoffmann: Tobacco Consumption and Lung Cancer; in: Lung Cancer. V. Advances in Basic and Clinical Research; edited by H. H. Hansen, Kluwer Aca-demic Publ., Boston, MA, 1994, pp. 1–42.10.1007/978-1-4615-2630-8_1Search in Google Scholar

593. Hoffmann, D., A. Rivenson, E. L. Wynder, and S. S. Hecht: Formation of tobacco-specific nitrosamines: Carcinogenic-ity, and the role of dietary fat in their carcinogenicity; in: Nitrosamines and Relat ed N- N it roso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and C. J. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 267–278.Search in Google Scholar

594. Hoffmann, D. and E. L. Wynder: Aktives und Passives Rauchen [Active and passive smoking]; in: Lehrbuch der Toxikologie; edited by H. Marquardt and S. G. Schaefer, B. I. Wissenschaftsverlag, Mannheim, Germany, 1994, pp. 589–605.Search in Google Scholar

595. Idris, A. M., B. Prokopczyk, and D. Hoffmann: Toombak: a major risk factor for cancer of the oral cavity in Sudan; Prev. Med. 23 (1994) 832–839.Search in Google Scholar

596. Murphy, S. E., S. G. Carmella, A. M. Idris, and D. Hoffmann: Uptake and metabolism of carcinogenic levels of tobacco-specific nitrosamines by Sudanese snuff dippers; Cancer Epidemiol. Biomarkers Prev. 3 (1994) 423–428.Search in Google Scholar

597. Prokopczyk, B., J. Krzeminski, and D. Hoffmann: Signifi-cance of nitrosamines in betel quid carcinogenesis; in: Nitrosamines and Related N-Nitroso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and C. J. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 365–366.Search in Google Scholar

598. Prokopczyk, B., M. Wu, J. E. Cox, S. Amin, D. Desai, and D. Hoffmann: The application of supercritical fluid extraction (SFE) for the determination of tobacco-specific nitrosamines in various tobacco samples. II. Optimization of the method-ology; presented at the 48th TCRC, Greensboro, NC, 1994, No. 45.Search in Google Scholar

599. Wynder, E. L. and D. Hoffmann: Smoking and lung cancer: Scientific challenges and opportunities; Cancer Res. 54 (1994) 5284–5295.Search in Google Scholar

600. Djordjevic, M. V., J. Fan, S. Ferguson, and D. Hoffmann: Self-regulation of smoking intensity. Smoke yields of the low-nicotine, low-“tar” cigarettes; Carcinogenesis 16 (1995) 2015–2021.Search in Google Scholar

601. Djordjevic, M. V., J. Fan, S. Ferguson, and D. Hoffmann: The chemical composition of mainstream cigarette smoke generated under FTC/CORESTA and actual human smoking (AHS) conditions; presented at the CORESTA Meet. Smoke-Techno Groups, Vienna, Austria, 1995, No. ST22.Search in Google Scholar

602. Djordjevic, M. V., J. Fan, and D. Hoffmann: Assessment of chlorinated pesticide residues in cigarette tobacco based on supercritical fluid extraction and GC-ECD; Carcinogenesis 16 (1995) 2627–2632.Search in Google Scholar

603. Djordjevic, M. V. and D. Hoffmann: Nicotine, pH, and N-nitrosamines in US commercial moist snuff brands; pre-sented at the 49th TCRC, Lexington, KY, 1995, No. 35.Search in Google Scholar

604. Djordjevic, M. V., D. Hoffmann, T. Glynn, and G. N. Con-nolly: US commercial brands of moist snuff, 1994. I. Assessment of nicotine, moisture, and pH; Tob. Control 4 (1995) 62–66.Search in Google Scholar

605. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: Changes in cigarette design and composition over time and how they influence the yields of smoke constituents; J. Smoking Rel. Disord. 6 (1995) 9–23.Search in Google Scholar

606. Hoffmann, D., M. V. Djordjevic, J. Fang, E. Zang, T. Glynn, and G. C. Connolly: Five leading US commercial brands of moist snuff in 1994: assessment of carcinogenic N-nitros-amines; J. Natl. Cancer Inst. 87 (1995) 1862–1869.Search in Google Scholar

607. Hoffmann, D. and I. Hoffmann: Tobacco consumption and lung cancer; Cancer Treat Res. 72 (1995) 1–42.Search in Google Scholar

608. Muscat, J. E., D. Hoffmann, and E. L. Wynder: The epidemi-ology of renal cell carcinoma: a second look; Cancer 75 (1995) 2552–2557.Search in Google Scholar

609. Prokopczyk, B, J. E. Cox, D. Pullo, and D. Hoffmann: GC-SRM-MS/MS for the analysis of TSNA in biological samples; presented at the 49th TCRC, Lexington, KY, 1995, No. 36.Search in Google Scholar

610. Prokopczyk, B., M. Wu, S. Amin, D. Desai, A. M. Idris, and D. Hoffmann: Improved methodology for the quantitative assessment of tobacco-specific N-nitrosamines in tobacco by supercritical fluid extraction; J. Agric. Food Chem. 43 (1995) 916–922.Search in Google Scholar

611. Safaev, R. D., D. G. Zaridze, D. Hoffmann, K. D. Brunne-mann, and Y. Liu: Efficiency and assessment of new cigarette filters. Chemical analysis of some of the toxic and carcinogenic agents in the mainstream smoke; Exper. Oncol. 17 (1995) 71–76.Search in Google Scholar

612. Amin, S., D. Desai, S. S. Hecht, and D. Hoffmann: Synthesis of tobacco-spec ific N-ni tr osamin es and their metabolites and results of related bioassays; Crit. Rev. Toxicol. 26 (1996) 139–147.Search in Google Scholar

613. Brunnemann, K. D., B. Prokopczyk, M. V. Djordjevic, and D. Hoffmann: Formation and analysis of tobacco-specific N-nitrosamines; Crit. Rev. Toxicol. 26 (1996) 121–137.Search in Google Scholar

614. Djordjevic, M. V., L. Eixarch, L. P. Bush, and D. Hoffmann: A comparison of the yields of selected components in the mainstream smoke of the leading US and Japanese ciga-rettes; presented at the CORESTA Congress Yokohama, Japan, 1996, No. S10; in: CORESTA Proc. Joint Smoke-Technology Groups, Yokohama, Japan, 1996, pp. 200–217.Search in Google Scholar

615. Djordjevic, M. V., J. Fan, S. Akerkar, J. Heidbrink, J. P. Richie Jr, and D. Hoffmann: Effects of smokers’ compen-sation for nicotine on mainstream smoke chemistry and urinary biomarkers of exposure; presented at the 50th TCRC, Richmond, VA, 1996, No. 64.Search in Google Scholar

616. El-Bayoumy, K., B. Prokopczyk, L. A. Peterson, D. Desai, S. Amin, B. S. Reddy, D. Hoffmann, and E. L. Wynder: Effects of dietary fat content on the metabolism of NNK and on DNA methylation induced by NNK; Nutr. Cancer, 26 (1996) 1–10.Search in Google Scholar

617. El-Bayoumy, K., P. Upadhyaya, D. H. Desai, S. Amin, D. Hoffmann, and E. L. Wynder: Effects of 1,4-phenylenebis-(methylene)selenocyanate, phenylethyl isothiocyanate, in-dole-3-carbinol, and d-limonene individually and in combi-nation on the tumorigenicity of the tobacco-specific nitros-amine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung; Anticancer Res. 16 (1996) 2709–2712.Search in Google Scholar

618. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: Changes in cigarette design and composition over time and how they influence the yields of smoke constituents; in: The FTC cigarette test method for determining tar, nicotine, and carbon monoxide yields of US cigarettes; NIH/NCI. Smoking and Tobacco Control Monogr. 7, NCI, Bethesda, MD, 1996, pp. 15–37.Search in Google Scholar

619. Hoffmann, D., A. A. Melikian, and E. L. Wynder: Scientific challenges in environmental carcinogenesis; Prev. Med. 25 (1996) 14–22.Search in Google Scholar

620. Hoffmann, D., A. Rivenson, and S. S. Hecht: The biological significance of tobacco-specific N-nitrosamines: smoking and adenocarcinoma of the lung; Crit. Rev. Toxicol. 26 (1996) 199–211.Search in Google Scholar

621. Lazarus, P., A. M. Idris, J. Kim, A. Calcagnotto, and D. Hoffmann: p53 mutations in head and neck squamous carcinomas from Sudanese snuff (Toombak) users; Cancer Detect. Prev. 20 (1996) 270-278.Search in Google Scholar

622. Prokopczyk, B., J. E. Cox, P. Upadhyaya, S. Amin, D. Desai, D. Hoffmann, and K. El-Bayoumy: Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methyl-nitrosamino)-1-(3-pyridy l)-1 -butanone-induced DNA adduct formation in lung and liver of A/J mice and F-344 rats; Carcinogenesis 17 (1996) 749-753.Search in Google Scholar

623. Djordjevic, M. V., L. Eixarch, and D. Hoffmann: Self-administered and effective dose of cigar smoke constituents; pres. at the 51st TCRC, Winston-Salem, NC, 1997, No. 9.Search in Google Scholar

624. Djordjevic, M. V., D. Hoffmann, S. Thompson, and S. D. Stellman: Distribution of smoking parameters and self-administered doses of select smoke components among different population groups; presented at the CORESTA Meet. Smoke-Techno Groups, Hamburg, 1997, No. ST7; in: CORESTA Proc. Smoke-Techno Groups, Hamburg, Germany, 1997, pp. 44-61.Search in Google Scholar

625. Djordjevic, M. V., D. Hoffmann, and I. Hoffmann: Nicotine regulates smoking patterns; Prev. Med. 26 (1997) 435–440.Search in Google Scholar

626. Hoffmann, D. and M. V. Djordjevic: Chemical composition and carcinogenicity of smokeless tobacco; Adv. Dental Res. 11 (1997) 322-329.Search in Google Scholar

627. Hoffmann, D., M. V. Djordjevic, and I. Hoffmann: The changing cigarette; Prev. Med. 26 (1997) 427–434.10.1006/pmed.1997.0183Search in Google Scholar

628. Hoffmann, D. and I. Hoffmann: [Chemical Studies on Tobacco Smoke. C] The changing cigarette, 1950-1995. J. Toxicol Environ. Health 50 (1997) 307-364.Search in Google Scholar

629. Hoffmann, D. and E. L. Wynder: Tobacco smoke; in: Ency clopaedia of Occupational Health and Safety; edited by J. Majer Stellman, ICLO Publications, Geneva, Switzerland. Vol. 2, 1997, pp. 44. 11–44. 14.Search in Google Scholar

630. Koppang, N., A. Rivenson, H. K. Dahle, and D. Hoffmann: A Study of Tobacco Carcinogenesis. LIII. Carcinogenicity of N’-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mink (Mustala vison); Cancer Lett. 111 (1997) 167-171.Search in Google Scholar

631. Muscat, J. E., S. D. Stellman, D. Hoffmann, and E. L. Wynder: Smoking and pancreatic cancer in men and women; Cancer Epidemiol. Biomarkers Prev. 6 (1997) 15-19.Search in Google Scholar

632. Prokopczyk, B., J. E. Cox, D. Hoffmann, and S. E. Waggoner: Identification of tobacco-specific carcinogen in the cervical mucus of smokers and nonsmokers; J. Natl. Cancer Inst. 89 (1997) 868-873.Search in Google Scholar

633. Stellman, S. D., J. E. Muscat, D. Hoffmann, and E. L. Wynder: Impact of filter cigarette smoking on lung cancer histology; Prev. Med. 26 (1997) 451–456.Search in Google Scholar

634. Stellman, S. D., J. E. Muscat, S. Thompson, D. Hoffmann, and E. L. Wynder: Risk of squamous cell carcinoma and adenocarcinoma of the lung in relation to lifetime filter cigarette smoking; Cancer 80 (1997) 382-388.Search in Google Scholar

635. Burnes, D. M., D. Hoffmann, and K. M. Cummings (Edi-tors): Cigar Smoking in the United States; NIH/NCI Smoking and Tobacco Control Monogr. 9, NCI, Bethesda, MD, 1998.Search in Google Scholar

636. Djordjevic, M. V., D. Hoffmann, S. Thompson, and S. D. Stellman:. Tobacco and mainstream smoke chemistry of the leading U. S. and Japanese cigarettes; presented at the 52nd Tobacco Science Research Conference (TSRC), Atlanta, GA, 1998, No. 59.Search in Google Scholar

637. Djordjevic, M. V., D. Hoffmann, S. Thompson, and S. D. Stellman: Smoking behavior and exposure to selected toxic agents among smokers of low- and medium-y ield cigarettes; presented at the CORESTA Congress Brighton, UK, 1998, No. ST16.Search in Google Scholar

638. Hecht, S. S. and D. Hoffmann: N-Nitroso compounds and man: sources of exposure, endogenous formation, and occurrence in body fluids; [Correspondence] Europ. J. Cancer Prev. 7 (1998) 165-166.Search in Google Scholar

639. Hoffmann, D. and I. Hoffmann: Letter to the Editor: Tobacco Smoke Components; Beitr. Tabakforsch. Int. 18 (1998) 49-52.Search in Google Scholar

640. Hoffmann, D. and I. Hoffmann: Chemistry and Toxicology; in: Cigar Smoking in the United States; edited by D. M. Burnes et al., Smoking and Tobacco Control Monograph 9, NCI, Bethesda, MD, 1998, pp. 55-104.Search in Google Scholar

641. Hoffmann, D., I. Hoffmann, and E. L. Wynder: The changing cigarette, 1950-1997: facts and expectations; in: Proc. Canadian Conf. of Cigarette Toxicity Reduction; edited by W. S. Rickert, Toronto, Canada, 1998, 94 p.Search in Google Scholar

642. Prokopczyk, B., D. Hoffmann, N. Trushin, J. E. Cox, K. El-Bayoumi, and S. Waggoner: In vitro studies on the metabo-lism of NNK in cervical tissue; presented at the 52nd TSRC, Atlanta, GA, 1998, No. 63.Search in Google Scholar

643. Wynder, E. L. and D. Hoffmann: Re: Cigarette Smoking and the Histopathology of Lung Cancer J. Natl. Cancer Inst. 90 (1998) 1486-1487.Search in Google Scholar

644. El-Bayoumy, K. and D. Hoffmann: Nutrition and tobacco-related cancer; in: Nutritional Oncology; edited by D. Heber et al., Academic Press, San Diego, CA, 1999, pp. 299-324.Search in Google Scholar

645. El-Bayoumy, K., M. Iatropoulos, S. Amin, D. Hoffmann, and E. L. Wynder: Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitros-amine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: the impact of a high-fat diet; Cancer Res. 59 (1999) 1400-1403.Search in Google Scholar

646. Hoffmann, D., S. Amin, K. D. Brunnemann, D. Desai, and A. C. Collins: On the modulation of nicotine: Studies on 2-methylnicotine; presented at the 53rd TSRC, Montreal, Canada, 1999, No. 29.Search in Google Scholar

647. Hoffmann, D. and I. Hoffmann: (Obituary) Ernst L. Wynder, MD, Dr Sc hc (mult) Dr med hc, 1922-1999; Tobacco Control 8 (1999) 444–445.Search in Google Scholar

648. Hoffmann, D. and E. L. Wynder: Active and Passive Smoking; in: Toxicology; edited by H. Marquardt et al, Academic Press, San Diego, CA, 1999, pp. 879-898.10.1016/B978-012473270-4/50095-XSearch in Google Scholar

649. Kagan, M. R., J. A. Cunningham, and D. Hoffmann: Propyl-ene glycol: a precursor of propylene oxide in cigarette smoke; presented at the 53rd TSRC, Montreal, Canada, 1999, No. 41.Search in Google Scholar

650. Melikian, AA., P. Sun, B. Prokopczyk, K. El-Bayoumy, D. Hoffmann, X. Wang, and S. Waggoner: Identification of benzo[a]pyrene metabolites in cervical mucus and DNA adducts in cervical tissues in humans by gas chroma-tography-mass spectrometry; Cancer Lett. 146 (1999) 127-134.Search in Google Scholar

651. Melikian, AA., X. Wang, S. Waggoner, D. Hoffmann, and K. El-Bayoumy: Comparative response of normal and of human papillomavirus-16 immortalized human epithelial cervical cells to benzo[a]pyrene; Oncol. Rep. 6 (1999) 1371-1376.Search in Google Scholar

652. Mitacek, EJ., K. D. Brunnemann, D. Hoffmann, T. Limsila, M. Suttajit, N. Martin, and L. S. Caplan: [Chemical Studies on Tobacco and Tobacco Smoke. CI.] Volatile nitrosamines and tobacco-specific nitrosamines in the smoke of Thai cigarettes: a risk factor for lung cancer and a suspected risk factor for liver cancer in Thailand; Carcinogenesis 20 (1999) 133-137.Search in Google Scholar

653. Baker, F., S. R. Ainsworth, J. T. Dye, C. Crammer, M. J. Thun, D. Hoffmann, J. L. Repace, J. E. Henningfield, J. Slade, J. Pinney, T. Shanks, D. M. Burns, G. N. Connolly, and D. R. Shopland: Health risks associated with cigar smoking; JAMA 284 (2000) 735-740.Search in Google Scholar

654. Brunnemann, K. D., J. Qi, and D. Hoffmann: Analytical comparison of two types of oral snuff; presented at the 54th TSRC, Nashville, TN, 2000, No. 40.Search in Google Scholar

655. Hecht, S. S. and D. Hoffmann: Re: Cigar smoking in men and risk of death from tobacco-related cancers; J. Natl. Cancer Inst. 92 (2000) 2040 [Comment on Shapiro et al.: J. Natl. Cancer Inst. 92 (2000) 333–337 and Boffetta et al.: J. Natl. Cancer Inst. 91 (1999) 697–701].Search in Google Scholar

656. Hoffmann, D. and I. Hoffmann: Ernst L. Wynder, M. D., Dr. Sc. h. c. (Mult.), Dr. med. h. c. - 1922–1999. Ein Nachruf; Soz. Präventivmed. 45 (2000) 61–63.Search in Google Scholar

657. Brunnemann, K. D., J. Qi, L. P. Bush, and D. Hoffmann: Alkaloid profile in oral moist snuff tobacco; presented at the 55th TSRC, Greensboro, NC, 2001, No. 41.Search in Google Scholar

658. Brunnemann, K. D., J. Qi, G. N. Connolly, and D. Hoffmann: Effects of storage on the levels of tobacco specific nitros-amines in oral moist snuff tobacco; presented at the 55th TSRC, Greensboro, NC, 2001, No. 40.10.1016/S0278-6915(02)00134-5Search in Google Scholar

659. Brunnemann, K. D, J. Qi, and D. Hoffmann: Aging of Oral Moist Snuff and the Yields of Tobacco-Specific N-Nitros-amines (TSNA); Progress Report, prepared for the Massachusetts Tobacco Control Program, Department of Public Health, Boston, MA, American Health Foundation, Valhalla, NY, 2001.Search in Google Scholar

660. Hoffmann, D. and I. Hoffmann: The Changing Cigarette. Chemical studies and bioassays; in: Risks Associated with Smoking Cigarettes with Low-Machine-Measured Yields of Tar and Nicotine. Smoking and Tobacco Control Monogr. 13, NCI, Bethesda, MD, 2001, pp. 159–191.Search in Google Scholar

661. Hoffmann, D., I. Hoffmann, and K. El-Bayoumy: The less harmful cigarette: a controversial issue. A tribute to Ernst L. Wynder; Chem. Res. Toxicol. 14 (2001) 767–790.Search in Google Scholar

662. Brunnemann, K. D., J. Qi, and D. Hoffmann: Chemical profile of two types of oral snuff tobacco; Food Chem. Toxicol. 40 (2002) 1699–1703.Search in Google Scholar

663. Prokopczyk, B., D. Hoffmann, M. Bologna, A. J. Cunning-ham, N. Trushin, S. Akerkar, T. Boyiri, S. Amin, D. Desai, S. Colosimo, B. Pittman, G. Leder, M. Ramadani, D. Henne-Bruns, H. G. Beger, and K. El-Bayoumy: Identification of tobacco-derived compounds in human pancreatic juice; Chem. Res. Toxicol. 15 (2002) 677–685.Search in Google Scholar

664. Brunnemann, K. D. J. Qi, and D. Hoffmann: Extraction of nicotine and TSNA from moist snuff by snuff dippers; presented at the 57th TSRC, Norfolk, VA, 2003, No. 20.Search in Google Scholar

665. Melikian, A. A., J. Hosey, J. Zhang, S. Colosimo, D. Hoffmann, M. Varga, J. H. Jaffe, and W. B. Barr: Reduction of urinary metabolites of tobacco carcinogens in smokers who switched from conventional light cigarettes to a new ciga-rette with low levels of tobacco-specific nitrosamines and a modified filter tip; in: Proc. Am. Assoc. Cancer Res., 2003, No. 6414.Search in Google Scholar

666. Brunnemann, K. D., J. Qi, and D. Hoffmann: Levels of TSNA in oral moist snuff in the past 30 years and today; presented on the 58th TSRC, Winston-Salem, NC, 2004, No. 38.Search in Google Scholar

667. El-Bayoumy, K., J. E. Muscat, and D. Hoffmann: Nutrition and tobacco-related cancer; in: Nutritional Oncology. (2nd Edition); edited by G. I. Blackburn et al., Academic Press, San Diego, CA, 2006, pp. 199–218.10.1016/B978-012088393-6/50066-XSearch in Google Scholar

668. Trushin, N., G. Leder, K. El-Bayoumy, D. Hoffmann, H. G. Beger, D. Henne-Bruns, M. Ramadani, B. Prokopczyk: The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols; Langenbecks Arch. Surg. 393 (2008) 571–579.Search in Google Scholar

669. Melikian, A. A. and D. Hoffmann: Smokeless tobacco: a gateway to smoking or a way away from smoking; presented at the Symposium for Aerosol Dynamics & Health, 2008, Cardiff University School of Biosciences, Wales, UK, Biomarkers, 14 Suppl. 1 (2009) 85–89.Search in Google Scholar

670. Schwartz, J. L, K. D. Brunnemann, A. J. Adami, S. Panda, S. C. Gordon, D. Hoffmann, G. R. Adami: Brand specific responses to smokeless tobacco in a rat lip canal model. J. Oral Pathol. Med. 39 (2010) 453–459.Search in Google Scholar

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