Open Access

Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes

Natalia Szysiak

Natalia Szysiak

Sub-Department of PathophysiologyLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Szysiak, Natalia
, 
Urszula Kosior-Korzecka

Urszula Kosior-Korzecka

Sub-Department of PathophysiologyLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Kosior-Korzecka, Urszula
, 
Vincenzo Longo

Vincenzo Longo

National Research Council, Institute of Agricultural Biology and Biotechnology, Research Unit of PisaPisa, Italy
Orcid profile
Search for this author on
Sciendo|Google Scholar
Longo, Vincenzo
, 
Krzysztof Patkowski

Krzysztof Patkowski

Department of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in LublinLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Patkowski, Krzysztof
, 
Monika Greguła-Kania

Monika Greguła-Kania

Department of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in LublinLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Greguła-Kania, Monika
, 
Aneta Nowakiewicz

Aneta Nowakiewicz

Sub-Department of Veterinary Microbiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary MedicineLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Nowakiewicz, Aneta
, 
Mariola Bochniarz

Mariola Bochniarz

Sub-Department of Veterinary Microbiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary MedicineLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Bochniarz, Mariola
 and 
Andrzej Junkuszew

Andrzej Junkuszew

Department of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in LublinLublin, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
Junkuszew, Andrzej
  
Jan 31, 2025
Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes's Cover Image
About this article
Previous Article
Next Article
Cite
Download Cover
Published Online: Jan 31, 2025
Page range: 121 - 129
Received: Jun 19, 2024
Accepted: Jan 23, 2025
DOI: https://doi.org/10.2478/jvetres-2025-0003
Keywords
© 2025 Natalia Szysiak et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

Fig. 1.

Role of kisspeptin-10 (KiSS-10), neurokinin B (NKB) and dynorphin (Dyn) A in the endocrine regulation of puberty, based on Navarro (20) and Pinilla et al. (24) ARC – arcuate nucleus; KNDy – kisspeptin, neurokinin B and dynorphin; GPR54 – G protein-related membrane receptor 54; NK3R – neurokinin 3 receptor; KOR – kappa opioid receptor; GnRH – gonadotropin-releasing hormone; LH – luteinising hormone; FSH – follicle-stimulating hormone; + – positive action; − – negative action; ? – unknown action
Role of kisspeptin-10 (KiSS-10), neurokinin B (NKB) and dynorphin (Dyn) A in the endocrine regulation of puberty, based on Navarro (20) and Pinilla et al. (24) ARC – arcuate nucleus; KNDy – kisspeptin, neurokinin B and dynorphin; GPR54 – G protein-related membrane receptor 54; NK3R – neurokinin 3 receptor; KOR – kappa opioid receptor; GnRH – gonadotropin-releasing hormone; LH – luteinising hormone; FSH – follicle-stimulating hormone; + – positive action; − – negative action; ? – unknown action

Fig. 2.

Influence of kisspeptin-10 (10−11–10−7 M) on luteinising hormone (LH) secretion from ovine pituitary cells in vitro a, b, c – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Influence of kisspeptin-10 (10−11–10−7 M) on luteinising hormone (LH) secretion from ovine pituitary cells in vitro a, b, c – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)

Fig. 3.

Influence of kisspeptin-10 (10−11–10−7 M) on follicle-stimulating hormone (FSH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Influence of kisspeptin-10 (10−11–10−7 M) on follicle-stimulating hormone (FSH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)

Fig. 4.

Influence of neurokinin B (10−11–10−7 M) on luteinising hormone (LH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Influence of neurokinin B (10−11–10−7 M) on luteinising hormone (LH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)

Fig. 5.

Influence of neurokinin B (10−11–10−7 M) on follicle-stimulating hormone (FSH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Influence of neurokinin B (10−11–10−7 M) on follicle-stimulating hormone (FSH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)

Fig. 6.

Influence of dynorphin A (10−11–10−7 M) on luteinising hormone (LH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Influence of dynorphin A (10−11–10−7 M) on luteinising hormone (LH) secretion from ovine pituitary cells in vitro a, b – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)

Fig. 7.

Influence of dynorphin A (10−11–10−7 M) on follicle-stimulating hormone (FSH) secretion from ovine pituitary cells in vitro a, b, c – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Influence of dynorphin A (10−11–10−7 M) on follicle-stimulating hormone (FSH) secretion from ovine pituitary cells in vitro a, b, c – mean values obtained at a specific incubation time marked with different letters differ statistically significantly (P-value ≤ 0.05)
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Life Sciences, Molecular Biology, Microbiology and Virology, Life Sciences, other, Medicine, Veterinary Medicine
Journal RSS Feed