Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Pharmaceutical Technology Department, Faculty of Pharmacy, Tanta UniversityTanta, Egypt
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Faculty of Medicine and Health Sciences, McGill UniversityMontreal, Quebec, Canada
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Prakash S, Rodes L, Coussa-Charley M, Tomaro-Duchesneau C. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biol: Targets Ther 2011; 5: 71-86.Search in Google Scholar
Chen Y, Zhou J, Wang L. Role and Mechanism of Gut Microbiota in Human Disease. Review. Front Cell Infect Microbiol 2021; 11: 625913.Search in Google Scholar
Jandhyala SM, Talukdar R, Subramanyam C, Vuyyuru H, Sasikala M, Nageshwar Reddy D. Role of the normal gut microbiota. World J Gastroenterol 2015; 21(29): 8787-8803.Search in Google Scholar
Westfall S, Lomis N, Prakash S. A polyphenol-rich prebiotic in combination with a novel probiotic formulation alleviates markers of obesity and diabetes in Drosophila. J Funct Foods 2018; 48: 374-386.Search in Google Scholar
Furman D, Campisi J, Verdin E, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med 2019; 25(12): 1822-1832.Search in Google Scholar
Green M, Arora K, Prakash S. Microbial Medicine: Prebiotic and Probiotic Functional Foods to Target Obesity and Metabolic Syndrome. Int J Mol Sci 2020; 21(8): 2890.Search in Google Scholar
Hill C, Guarner F, Reid G, et al. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol 2014; 11(8): 506-514.Search in Google Scholar
Singh RK, Chang H-W, Yan D, et al. Influence of diet on the gut microbiome and implications for human health. J Transl Med 2017; 15(1): 73.Search in Google Scholar
Markowiak-Kopeć P, Śliżewska K. The Effect of Probiotics on the Production of Short-Chain Fatty Acids by Human Intestinal Microbiome. Nutrients 2020; 12(4): 1107.Search in Google Scholar
Hoffmann A, Kleniewska P, Pawliczak R. Antioxidative activity of probiotics. Arch Med Sci 2021; 17(3): 792-804.Search in Google Scholar
Kechagia M, Basoulis D, Konstantopoulou S, et al. Health benefits of probiotics: a review. ISRN Nutr 2013; 2013: 481651.Search in Google Scholar
Cristofori F, Dargenio VN, Dargenio C, Miniello VL, Barone M, Francavilla R. Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body. Front Immunol 2021; 12: 578386.Search in Google Scholar
Arora K, Green M, Prakash S. The Microbiome and Alzheimer’s Disease: Potential and Limitations of Prebiotic, Synbiotic, and Probiotic Formulations. Front Bioeng Biotechnol 2020; 8: 537847.Search in Google Scholar
Iqbal UH, Westfall S, Prakash S. Novel microencapsulated probiotic blend for use in metabolic syndrome: design and in-vivo analysis. Artif Cells Nanomed Biotechnol 2018; 46(sup3): S116-S124.Search in Google Scholar
Mariman R, Reefman E, Tielen F, et al. Lactobacillus plantarum NCIMB8826 ameliorates inflammation of colon and skin in human APOC1 transgenic mice. Benef Microbes 2016; 7(2): 215-25.Search in Google Scholar
Tomaro-Duchesneau C, Saha S, Malhotra M, et al. Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization. Pharmaceuticals (Basel) 2012; 5(2): 236-48.Search in Google Scholar
Tomaro-Duchesneau C, Saha S, Malhotra M, et al. Effect of orally administered L. fermentum NCIMB 5221 on markers of metabolic syndrome: an in vivo analysis using ZDF rats. Appl Microbiol Biotechnol 2014; 98(1): 115-26.Search in Google Scholar
Kim J, Yun JM, Kim MK, Kwon O, Cho B. Lactobacillus gasseri BNR17 Supplementation Reduces the Visceral Fat Accumulation and Waist Circumference in Obese Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Med Food 2018; 21(5): 454-461., Kang JH, Yun SI, Park HO. Effects of Lactobacillus gasseri BNR17 on body weight and adipose tissue mass in diet-induced overweight rats. J Microbiol 2010; 48(5): 712-4.Search in Google Scholar
Kawano M, Miyoshi M, Ogawa A, Sakai F, Kadooka Y. Lactobacillus gasseri SBT2055 inhibits adipose tissue inflammation and intestinal permeability in mice fed a high-fat diet. J Nutr Sci 2016; 5: e23.Search in Google Scholar
Carroll IM, Andrus JM, Bruno-Bárcena JM, Klaenhammer TR, Hassan HM, Threadgill DS. Anti-inflammatory properties of Lactobacillus gasseri expressing manganese superoxide dismutase using the interleukin 10-deficient mouse model of colitis. Am J Physiol Gastrointest Liver Physiol 2007; 293(4): G729-G738.Search in Google Scholar
Izuddin WI, Humam AM, Loh TC, Foo HL, Samsudin AA. Dietary Postbiotic Lactobacillus plantarum Improves Serum and Ruminal Antioxidant Activity and Upregulates Hepatic Antioxidant Enzymes and Ruminal Barrier Function in Post-Weaning Lambs. Antioxidants. 2020;9(3).Search in Google Scholar
Mohebali N, Ekat K, Kreikemeyer B, Breitrück A. Barrier Protection and Recovery Effects of Gut Commensal Bacteria on Differentiated Intestinal Epithelial Cells In Vitro. Nutrients 2020; 12(8): 2251.Search in Google Scholar
Monteagudo-Mera A, Rastall RA, Gibson GR, Charalampopoulos D, Chatzifragkou A. Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health. Appl Microbiol Biotechnol 2019; 103(16): 6463-6472.Search in Google Scholar
Van Tassell ML, Miller MJ. Lactobacillus Adhesion to Mucus. Nutrients 2011; 3(5): 613-636.Search in Google Scholar
Monteagudo-Mera A, Rastall RA, Gibson GR, Charalampopoulos D, Chatzifragkou A. Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health. Appl Microbiol Biotechnol 2019; 103(16): 6463-6472.Search in Google Scholar
Tomaro-Duchesneau C, Saha S, Malhotra M, Jones ML, Rodes L, Prakash S. Lactobacillus fermentum NCIMB 5221 and NCIMB 2797 as cholesterol-lowering probiotic biotherapeutics: in vitro analysis. Benef Microbes 2015; 6(6): 861-869., Zawistowska-Rojek A, Kośmider A, Stępień K, Tyski S. Adhesion and aggregation properties of Lactobacillaceae strains as protection ways against enteropathogenic bacteria. Arch Microbiol 2022; 204(5): 285., Pan M, Hidalgo-Cantabrana C, Goh YJ, Sanozky-Dawes R, Barrangou R. Comparative Analysis of Lactobacillus gasseri and Lactobacillus crispatus Isolated From Human Urogenital and Gastrointestinal Tracts. Front Microbiol 2019; 10: 3146.Search in Google Scholar
Gharbi Y, Fhoula I, Ruas-Madiedo P, et al. In-vitro characterization of potentially probiotic Lactobacillus strains isolated from human microbiota: interaction with pathogenic bacteria and the enteric cell line HT29. Ann Microbiol 2019; 69(1): 61-72.Search in Google Scholar
Muscariello L, De Siena B, Marasco R. Lactobacillus Cell Surface Proteins Involved in Interaction with Mucus and Extracellular Matrix Components. Curr Microbiol 2020; 77(12): 3831-3841.Search in Google Scholar
Hynönen U, Palva A. Lactobacillus surface layer proteins: structure, function and applications. Appl Microbiol Biotechnol 2013; 97(12): 5225-5243.Search in Google Scholar
Hussain T, Tan B, Yin Y, Blachier F, Tossou MCB, Rahu N. Oxidative Stress and Inflammation: What Polyphenols Can Do for Us? Oxid Med Cell Longev 2016; 2016(1): 7432797.Search in Google Scholar
Musazadeh V, Faghfouri AH, Zarezadeh M, et al. Remarkable impacts of probiotics supplementation in enhancing of the antioxidant status: results of an umbrella meta-analysis. Systematic Review. Front Nutr 2023; 10: 1117387.Search in Google Scholar
Gulcin İ, Alwasel SH. DPPH Radical Scavenging Assay. Processes 2023; 11(8): 2248.Search in Google Scholar
33. D’Andrea G. Quercetin: A flavonol with multifaceted therapeutic applications? Fitoterapia 2015; 106: 256-271.Search in Google Scholar
Kleerebezem M, Boekhorst J, van Kranenburg R, et al. Complete genome sequence of Lactobacillus plantarum WCFS1. Proceedings of the National Academy of Sciences 2003; 100(4): 1990-1995.Search in Google Scholar
Prete R, Garcia-Gonzalez N, Di Mattia CD, Corsetti A, Battista N. Food-borne Lactiplantibacillus plantarum protect normal intestinal cells against inflammation by modulating reactive oxygen species and IL-23/IL-17 axis. Sci Rep 2020; 10(1): 16340.Search in Google Scholar
Tomaro-Duchesneau C, Saha S, Malhotra M, et al. Lactobacillus fermentum NCIMB 5221 has a greater potential for the production of ferulic acid when compared to other ferulic acid esterase active Lactobacilli. Int J Probiotics Prebiotics 2012; 7: 23-32.Search in Google Scholar
Tomaro-Duchesneau C, Saha S, Malhotra M, et al. Effect of orally administered L. fermentum NCIMB 5221 on markers of metabolic syndrome: an in vivo analysis using ZDF rats. Appl Microbiol Biotechnol 2014; 98(1): 115-26.Search in Google Scholar
Liang L, Meng Z, Zhang F, et al. Lactobacillus gasseri LG08 and Leuconostoc mesenteroides LM58 exert preventive effect on the development of hyperuricemia by repairing antioxidant system and intestinal flora balance. Front Microbiol 2023; 14: 1211831.Search in Google Scholar
Karimkhani MM, Jamshidi A, Nasrollahzadeh M, Armin M, Jafari SM, Zeinali T. Fermentation of Rubus dolichocarpus juice using Lactobacillus gasseri and Lacticaseibacillus casei and protecting phenolic compounds by Stevia extract during cold storage. Sci Rep 2024; 14(1): 5711.Search in Google Scholar
Vougiouklaki D, Loka K, Tsakni A, Houhoula D. Characterization of Metabolites Production by Lactobacillus Gasseri ATCC 33323 and Antioxidant Activity. NFSIJ 2022; 11(3): 555815.Search in Google Scholar
Kaper JB, Nataro JP, Mobley HLT. Pathogenic Escherichia coli. Nat Rev Microbiol 2004; 2(2): 123-140.Search in Google Scholar
Matsushima K, Shichino S, Ueha S. Thirty-five years since the discovery of chemotactic cytokines, interleukin-8 and MCAF: A historical overview. Proc Jpn Acad Ser B Phys Biol Sci 2023; 99(7): 213-226.Search in Google Scholar
Sun L, Tian W, Guo X, et al. Lactobacillus gasseri JM1 with potential probiotic characteristics alleviates inflammatory response by activating the PI3K/Akt signaling pathway in vitro. JDS 2020; 103(9): 7851-7864.Search in Google Scholar
van den Nieuwboer M, van Hemert S, Claassen E, de Vos WM. Lactobacillus plantarum WCFS1 and its host interaction: a dozen years after the genome. Microb Biotechnol 2016; 9(4): 452-465., Fang C, Kim H, Yanagisawa L, et al. Gallotannins and Lactobacillus plantarum WCFS1 Mitigate High-Fat Diet-Induced Inflammation and Induce Biomarkers for Thermogenesis in Adipose Tissue in Gnotobiotic Mice. Mol Nutr Food Res 2019; 63(9): 1800937.Search in Google Scholar
Kahouli I, Malhotra M, Tomaro-Duchesneau C, Rodes L, Aloui-Jamali M, Prakash S. Identification of Lactobacillus Fermentum Strains with Potential against Colorectal Cancer by Characterizing Short Chain Fatty Acids Production, Anti-Proliferative Activity and Survival in an Intestinal Fluid: In Vitro Analysis. JBABM 2015; 7: 104-115.Search in Google Scholar
Shin Y, Han S, Kwon J, et al. Roles of Short-Chain Fatty Acids in Inflammatory Bowel Disease. Nutrients 2023; 15(20): 4466.Search in Google Scholar
Gebremariam HG, Qazi KR, Somiah T, et al. Lactobacillus gasseri Suppresses the Production of Proinflammatory Cytokines in Helicobacter pylori-Infected Macrophages by Inhibiting the Expression of ADAM17. Front Immunol 2019; 10: 2326.Search in Google Scholar
Bermudez-Brito M, Borghuis T, Daniel C, et al. L. plantarum WCFS1 enhances Treg frequencies by activating DCs even in absence of sampling of bacteria in the Peyer Patches. Sci Rep 2018; 8(1): 1785.Search in Google Scholar
