Formerly: Beiträge zur Tabakforschung International

Contributions to Tobacco & Nicotine Research

Contributions to Tob. Res.

<abstract xml:lang="en"><title style='display:none'>Abstract</title> A method for the determination of nicotine in lung tissue is presented. The nicotine is extracted from homogenized lung tissue by means of a mixture of hydrochloric acid and methanol. It is then spectrophotometrically determined after the disturbing accompanying substances have been eliminated by a preliminary acid steam distillation. The method's inferior limit of detection is 40 µg of nicotine contained in 3 lungs, which corresponds to 17.7 µg of nicotine per gramme of lung tissue. In the case of nicotine contents of 50 µg per analytical procedure the standard deviation of the method was found to be 1.7 µg, and the resulting coefficient of variation was calculated to be 3.4 %. The procedure is simple and therefore suitable for the study of numerous samples. The exposure of hamsters to inhaled raw cigarette smoke revealed that the nicotine content of lungs of experimental animals augments with the number of burnt cigarettes and the duration of inhalation. The reproducibility of Dontenwill's inhalation procedure was tested and proved to be satisfactory. The coefficient of variation within two series of inhalation experiments was found to be between 4.1 and 5.2 %</abstract>

Abstract

Institut der Wissenschaftlichen Forschungsstelle im Verband der Cigarettenindustrie, Hamburg, Germany

<article-title>A Method for the Determination of Nicotine in Lung Tissue of Hamsters / Eine Methode zur Bestimmung des Nikotins in Hamsterlungen</article-title>

A Method for the Determination of Nicotine in Lung Tissue of Hamsters / Eine Methode zur Bestimmung des Nikotins in Hamsterlungen

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Contributions to Tobacco and Nicotine Research ist in den folgenden Services indiziert: <UL> <LI>Baidu Scholar </LI> <LI>CABI (over 50 subsections) </LI> <LI>Chemical Abstracts Service (CAS) - CAplus </LI> <LI>Chemical Abstracts Service (CAS) - SciFinder </LI> <LI>CNKI Scholar (China National Knowledge Infrastructure) </LI> <LI>CNPIEC - cnpLINKer </LI> <LI>Dimensions </LI> <LI>DOAJ (Directory of Open Access Journals) </LI> <LI>EBSCO </LI> <LI>Elsevier - Reaxys </LI> <LI>ExLibris </LI> <LI>Google Scholar </LI> <LI>Japan Science and Technology Agency (JST) </LI> <LI>J-Gate </LI> <LI>JournalGuide </LI> <LI>KESLI-NDSL (Korean National Discovery for Science Leaders) </LI> <LI>MyScienceWork </LI> <LI>Naver Academic </LI> <LI>Naviga (Softweco) </LI> <LI>QOAM (Quality Open Access Market) </LI> <LI>ReadCube </LI> <LI>SCILIT </LI> <LI>SCImago (SJR) </LI> <LI>SCOPUS </LI> <LI>Semantic Scholar </LI> <LI>TDNet </LI> <LI>Ulrich's Periodicals Directory/ulrichsweb </LI> <LI>WanFang Data </LI> <LI>Web of Science - Biological Abstracts </LI> <LI>Web of Science - BIOSIS Previews </LI> <LI>WorldCat (OCLC) </LI> <LI>X-MOL </LI></UL>

Advisory Board　　　 Bernhard Eitzinger, delfortgroup AG, Traun, Austria Ernest Groman, University of Vienna, Vienna, Austria Daniel Heck, HeckTox LLC, Greensboro, NC, USA Anne Fisher, University of Kentucky, Lexington, KY, USA Xie Jianping, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China Hubert Klus, St. Pölten, Austria John H. Lauterbach, Lauterbach &amp; Associates LLC, Macon, GA, USA Ramsey Lewis, North Carolina State University, Raleigh, NC, USA Chuan Liu, Southampton, UK Tryggve Ljung, Swedish Match, Stockholm, Sweden Michael W. Ogden, Ogden Ology, LLC, Lewisville, NC, USA Thilo Paschke, Geneva, Switzerland Stephen W. Purkis, Bristol, UK Elmar Richter †, Ludwig-Maximilians-University, Munich, Germany Wolfram Roeper, Hamburg, Germany Wolfgang Trinkies, Bayreuth, Germany Andreas Zemann, Leopold-Franzens-University of Innsbruck, Innsbruck, Austria Editors Wolf-Dieter Heller Gerhard Scherer Editorial Office Barbara Boenke Brigitte Müller Anja Thielen Contact <A href="mailto:editors@beitraege-bti.de">editors@beitraege-bti.de</A> Publisher De Gruyter Poland Bogumiła Zuga 32A Str. 01-811 Warsaw, Poland T: +48 22 701 50 15

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Contributions to Tobacco and Nicotine Research (formerly: Beiträge zur Tabakforschung International / Contribution to Tobacco Research International) publishes articles with a focus on tobacco, nicotine, and related consumer products. In addition, all aspects of research on the tobacco plant as well as on product technology and manufacturing are relevant for the Journal. Products of interest comprise (i) combustible tobacco products (cigarettes, cigars, pipes, etc.), (ii) smokeless tobacco (SLT) products (snuff, snus, chewing tobacco, etc.), (iii) tobacco heating products (THP), (iv) electronic cigarettes (e-cigs, w/o nicotine), (v) oral nicotine delivery (OND) products. All scientific investigations on product-related properties (including physical, chemical, biological, and toxicological properties) as well as on the influence on consumers’ behavior and response (including acute and long-term product use patterns and biomarker profiles) are considered for publication. Submissions can be of the following types: original investigations, reviews, short reports commentaries, letters to the editor. Fields covered by the Journal <UL> <LI>Research into the tobacco plant </LI> <UL> <LI>Tobacco plant </LI> <LI>Metabolism </LI> <LI>Cultivation </LI> <LI>Pesticides Biotechnology (Plant pathology, Mycology, Microbiology) </LI> </UL></UL> <UL> <LI>Manufacture of tobacco products </LI> <UL> <LI>Processing of tobacco </LI> <LI>Flavor </LI> <LI>Manufacture of cigarettes and other products </LI> <LI>Tobacco and environment </LI> <LI>Chemical engineering including physical chemistry </LI> </UL></UL> <UL> <LI>Analysis and properties of tobacco smoke </LI> <UL> <LI>Physical properties </LI> <LI>Chemical properties </LI> <LI>Combustion studies </LI> <LI>Mainstream/sidestream smoke </LI> <LI>Filter studies </LI> <LI>Special substances </LI> <LI>Analytical methods </LI> <LI>Machine smoking </LI> </UL></UL> <UL> <LI>Tobacco products other than cigarettes </LI> <UL> <LI>Cigars / cigarillos </LI> <LI>Pipe tobacco </LI> <LI>Smokeless tobacco (SLT) products (snuff, snus, chewing tobacco) </LI></UL> <LI>New products </LI> <UL> <LI>Tobacco heating products (THP) </LI> <LI>Electronic cigarettes (e-cigs, w/o nicotine) </LI> <LI>Oral nicotine devices (OND, e.g., nicotine pouches) </LI> </UL></UL> <UL> <LI>Human smoking behavior </LI> <UL> <LI>Biomonitoring </LI> <LI>Consumer behavior </LI></UL></UL> Open Access Statement The journal is an Open Access journal that allows a free unlimited access to all its contents without any restrictions upon publication to all users. Archiving Sciendo archives the contents of this journal in <A href="https://www.portico.org/">Portico</A> - digital long-term preservation service of scholarly books, journals and collections. Plagiarism Policy The editorial board is participating in a growing community of <A href="https://www.crossref.org/services/similarity-check/">Similarity Check System's</A> users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process.

Contributions to Tobacco & Nicotine Research

A Method for the Determination of Nicotine in Lung Tissue of Hamsters / Eine Methode zur Bestimmung des Nikotins in Hamsterlungen

H. Elmenhorst
H. Elmenhorst

Published Online: 13 Jun 2014

Volume & Issue: Volume 3 (1966) - Issue 6 (September 1966)

Page range: 449 - 453

Journal & Issue Details

Contributions to Tobacco & Nicotine Research

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Recent Articles

Contributions to Tobacco & Nicotine Research

A Method for the Determination of Nicotine in Lung Tissue of Hamsters / Eine Methode zur Bestimmung des Nikotins in Hamsterlungen

H. ElmenhorstH. Elmenhorst

Published Online: 13 Jun 2014

Volume & Issue: Volume 3 (1966) - Issue 6 (September 1966)

Page range: 449 - 453

Journal & Issue Details

Contributions to Tobacco & Nicotine Research

PDF Preview

References

Recent Articles

H. Elmenhorst
H. Elmenhorst